Search Results - "Silva, Patrícia M.R."

Inhibition of advanced glycation end products by aminoguanidine restores mast cell numbers and reactivity in alloxan-diabetic rats by Carvalho, Vinicius F., Florim, Luisa T., de O. Barreto, Emiliano, Torres, Rafael C., Batista, Marcelo M., Amendoeira, Fabio C., Cordeiro, Renato S.B., Martins, Marco A., e Silva, Patrícia M.R.

“…Mast cell number and reactivity have been shown to be down-regulated under diabetic conditions. This study was undertaken in order to investigate the role of…”
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Activation of PPARγ by restores mast cell numbers and reactivity in alloxan-diabetic rats by reducing the systemic glucocorticoid levels by Torres, Rafael C., Batista, Marcelo M., Pons, Andrea H., Silva, Adriana R., Cordeiro, Renato S.B., Martins, Marco A., e Silva, Patrícia M.R., Carvalho, Vinicius F.

“…Mast cell function and survival have been shown to be down-regulated under diabetic conditions. This study investigates the role of the peroxisome…”
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Different strains of mice present distinct lung tissue mechanics and extracellular matrix composition in a model of chronic allergic asthma by Antunes, Mariana A, Abreu, Soraia C, Damaceno-Rodrigues, Nilsa R, Parra, Edwin R, Capelozzi, Vera L, Pinart, Mariona, Romero, Pablo V, Silva, Patrícia M.R, Martins, Marco Aurélio, Rocco, Patricia R.M

“…Abstract The impact of genetic factors on asthma is well recognized but poorly understood. We tested the hypothesis that different mouse strains present…”
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Impact of obesity on airway and lung parenchyma remodeling in experimental chronic allergic asthma by Saraiva, Simone A, Silva, Adriana L, Xisto, Débora G, Abreu, Soraia C, Silva, Johnatas D, Silva, Pedro L, Teixeira, Tatiana P.F, Parra, Edwin R, Carvalho, Ana Laura N, Annoni, Raquel, Mauad, Thais, Capelozzi, Vera L, Silva, Patricia M.R, Martins, Marco A, Rocco, Patricia R.M

“…Abstract The impact of obesity on the inflammatory process has been described in asthma, however little is known about the influence of diet-induced obesity on…”
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Blame the signaling: Role of cAMP for the resolution of inflammation by Tavares, Luciana P., Negreiros-Lima, Graziele L., Lima, Kátia M., E Silva, Patrícia M.R., Pinho, Vanessa, Teixeira, Mauro M., Sousa, Lirlândia P.

“…[Display omitted] A complex intracellular signaling governs different cellular responses in inflammation. Extracellular stimuli are sensed, amplified, and…”
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Combined action of vasoactive amines and bradykinin mediates allergen-evoked thermal hyperalgesia in rats by Lavich, Tatiana R, Cordeiro, Renato S.B, Calixto, João B, e Silva, Patrı́cia M.R, Martins, Marco A

“…The ability of allergens to induce hyperalgesia in immunoglobulin E (IgE)-sensitized rats was investigated. The left hind paws of Wistar rats were sensitized…”
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Increased levels of cyclic adenosine monophosphate contribute to the hyporesponsiveness of mast cells in alloxan diabetes by Barreto, Emiliano O, Carvalho, Vinicius F, Lagente, Vincent, Lugnier, Claire, Cordeiro, Renato S.B, Martins, Marco A, e Silva, Patrı́cia M.R

“…In this study, we investigated the influence of intracellular cyclic adenosine monophosphate (cAMP) changes on the rat mast cell hyporesponsiveness following…”
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Diabetes Downregulates Allergen-Induced Airway Inflammation in Mice by Silva, Patrícia M. R. e, Martins, Marco A., Jannini-Sá, Yago A. P., Ferreira, Tatiana Paula T., Serra, Magda F., Arantes, Ana Carolina S., Barreto, Emiliano O., Carvalho, Vinicius F., Hogaboam, Cory M.

“…Previous studies described that allergic diseases, including asthma, occur less often than expected in patients with type 1 diabetes. Here, we investigated the…”
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The role and effects of glucocorticoid-induced leucine zipper in the context of inflammation resolution by Vago, Juliana P, Tavares, Luciana P, Garcia, Cristiana C, Lima, Kátia M, Perucci, Luiza O, Vieira, Érica L, Nogueira, Camila R C, Soriani, Frederico M, Martins, Joilson O, Silva, Patrícia M R, Gomes, Karina B, Pinho, Vanessa, Bruscoli, Stefano, Riccardi, Carlo, Beaulieu, Elaine, Morand, Eric F, Teixeira, Mauro M, Sousa, Lirlândia P

“…Glucocorticoid (GC)-induced leucine zipper (GILZ) has been shown to mediate or mimic several actions of GC. This study assessed the role of GILZ in…”
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Gold nanoparticles reduce tubule-interstitial injury and proteinuria in a murine model of subclinical acute kidney injury by Peres, Rodrigo A.S., Silva-Aguiar, Rodrigo P., Teixeira, Douglas E., Peruchetti, Diogo B., Alves, Sarah A.S., Leal, Anna Beatriz C., Castro, Guilherme F., Ribeiro, Natalia B.S., Guimarães, Fernanda V., Pinheiro, Ana Acacia S., Silva, Patrícia M.R. e, Martins, Marco A., Caruso-Neves, Celso

“…Subclinical acute kidney injury (subAKI) is characterized by tubule-interstitial injury without significant changes in glomerular function. SubAKI is…”
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Activation of PPARγ reduces N-acetyl-cysteine -induced hypercorticoidism by down-regulating MC2R expression into adrenal glands by Ventura, Raíssa D., Chaves, Amanda S., Magalhães, Nathalia S., Gonzalez, Florencia B., Pacini, Maria Florencia, Pérez, Ana Rosa, Silva, Patrícia M.R., Martins, Marco A., Carvalho, Vinicius F.

“…We previously demonstrated that oral supplementation with antioxidants induced hyperactivity of hypothalamus-pituitary-adrenal (HPA) axis, attested by…”
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Glucocorticoids decrease the numbers and activation of mast cells by inducing the transactivation receptors of AGEs by Santoro, Tassia, Azevedo, Carolina T., e Silva, Patrícia M. R., Martins, Marco A., Carvalho, Vinicius F.

“…Glucocorticoids (GCs) are potent anti‐allergic compounds that function, at least in part, by inhibiting signaling pathways in mast cells. We hypothesized that…”
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Inhibition of Phosphodiesterase-4 during Pneumococcal Pneumonia Reduces Inflammation and Lung Injury in Mice by Tavares, Luciana P, Garcia, Cristiana C, Vago, Juliana P, Queiroz-Junior, Celso M, Galvão, Izabela, David, Bruna A, Rachid, Milene A, Silva, Patrícia M R, Russo, Remo C, Teixeira, Mauro M, Sousa, Lirlândia P

“…Pneumococcal pneumonia is a leading cause of mortality worldwide. The inflammatory response to bacteria is necessary to control infection, but it may also…”
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Activation of PPAR-γ reduces HPA axis activity in diabetic rats by up-regulating PI3K expression by Torres, Rafael Carvalho, Magalhães, Nathalia Santos, e Silva, Patrícia M.R., Martins, Marco A., Carvalho, Vinicius F.

“…Increased hypothalamus-pituitary-adrenal axis (HPA) activity in diabetes is strongly associated with several morbidities noted in patients with the disease. We…”
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Annexin A1 Is Involved in the Resolution of Inflammatory Responses during Leishmania braziliensis Infection by Oliveira, Leandro G, Souza-Testasicca, Míriam C, Vago, Juliana P, Figueiredo, Amanda Braga, Canavaci, Adriana M C, Perucci, Luiza Oliveira, Ferreira, Tatiana P Teixeira, Coelho, Eduardo A F, Gonçalves, Denise Utsch, Rocha, Manoel Otávio C, E Silva, Patrícia M R, Ferreira, Cláudia N, Queiroz-Junior, Celso, Sousa, Lirlândia P, Fernandes, Ana Paula

“…Leishmaniases are diseases caused by several species. ( ) can cause localized cutaneous leishmaniasis (LCL), which heals spontaneously, or mucosal…”
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α-bisabolol-loaded lipid-core nanocapsules reduce lipopolysaccharide-induced pulmonary inflammation in mice by D'Almeida, Ana Paula L, Pacheco de Oliveira, Maria T, de Souza, Éverton T, de Sá Coutinho, Diego, Ciambarella, Bianca T, Gomes, Cristiano R, Terroso, Thatiana, Guterres, Sílvia S, Pohlmann, Adriana R, Silva, Patrícia Mr, Martins, Marco A, Bernardi, Andressa

“…Acute respiratory distress syndrome (ARDS) is a severe clinical condition of respiratory failure due to an intense inflammatory response with different…”
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Systemic and local dexamethasone treatments prevent allergic eosinophilia in rats via distinct mechanisms by Pasquale, Claudia P, Lima, Marcia C.R, Bandeira-Melo, Christianne, Cordeiro, Renato S.B, e Silva, Patrı́cia M.R, Martins, Marco A

“…We have studied the effect of local and systemic treatment with dexamethasone for prevention of the pleural eosinophilia triggered by allergen in actively…”
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Capsaicin inhibits lipopolysaccharide-induced adrenal steroidogenesis by raising intracellular calcium levels by Ferreira, Leonardo G. B., Prevatto, Jessika P., Freitas, Hercules R., Reis, Ricardo A. M., Silva, Patrícia M. R., Martins, Marco A., Faria, Robson X., Carvalho, Vinicius F.

“…Introduction Glucocorticoid release by adrenals has been described as significant to survive sepsis. The activation of transient receptor potential vanilloid…”
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15-Deoxy-Delta-12,14-Prostaglandin J2 Inhibits Lung Inflammation and Remodeling in Distinct Murine Models of Asthma by Coutinho, Diego S., Anjos-Valotta, Edna A., do Nascimento, Caio V. M. F., Pires, Ana Lucia A., Napimoga, Marcelo H., Carvalho, Vinícius F., Torres, Rafael C., e Silva, Patrícia M. R., Martins, Marco A.

“…15-deoxy-Δ-12,14-prostaglandin J2 (15d-PGJ2) has been described as an anti-inflammatory lipid mediator in several in vitro and in vivo studies, but its effect…”
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Involvement of prostaglandins in the down‐regulation of allergic plasma leakage observed in rats undergoing pleural eosinophilia by Bandeira‐Melo, Christianne, Singh, Yajaira, Cordeiro, Renato S.B., Silva, Patrícia M.R., Martins, Marco A.

“…1 Recent evidence has implicated eosinophils in the inhibition of allergen‐induced rat pleurisy, but the mechanism of this negative modulation is not…”
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