Search Results - "Silva, Odete A B da Cruz E"

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    Exosome isolation from distinct biofluids using precipitation and column-based approaches by Soares Martins, Tânia, Catita, José, Martins Rosa, Ilka, A B da Cruz E Silva, Odete, Henriques, Ana Gabriela

    Published in PloS one (11-06-2018)
    “…The potential of exosomes as biomarker resources for diagnostics, prognostics and even for therapeutics is an area of intense research. Despite the various…”
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    Nuclear Envelope Alterations in Myotonic Dystrophy Type 1 Patient-Derived Fibroblasts by Viegas, Diana, Pereira, Cátia D, Martins, Filipa, Mateus, Tiago, da Cruz E Silva, Odete A B, Herdeiro, Maria Teresa, Rebelo, Sandra

    “…Myotonic dystrophy type 1 (DM1) is a hereditary and multisystemic disease characterized by myotonia, progressive distal muscle weakness and atrophy. The…”
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    Nuclear envelope dysfunction and its contribution to the aging process by Martins, Filipa, Sousa, Jéssica, Pereira, Cátia D., Cruz e Silva, Odete A. B., Rebelo, Sandra

    Published in Aging cell (01-05-2020)
    “…The nuclear envelope (NE) is the central organizing unit of the eukaryotic cell serving as a genome protective barrier and mechanotransduction interface…”
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    Bioinformatic analysis of the SPs and NFTs proteomes unravel putative biomarker candidates for Alzheimer's disease by Ferreira, Maria J. Cardoso, Soares Martins, Tânia, Alves, Steven R., Rosa, Ilka Martins, Vogelgsang, Jonathan, Hansen, Niels, Wiltfang, Jens, da Cruz e Silva, Odete A. B., Vitorino, Rui, Henriques, Ana Gabriela

    Published in Proteomics (Weinheim) (01-08-2023)
    “…Aging is the main risk factor for the appearance of age‐related neurodegenerative diseases, including Alzheimer's disease (AD). AD is the most common form of…”
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    Nuclear envelope dynamics during mammalian spermatogenesis: new insights on male fertility by Pereira, Cátia D., Serrano, Joana B., Martins, Filipa, Cruz e Silva, Odete A. B., Rebelo, Sandra

    “…ABSTRACT The production of highly specialized spermatozoa from undifferentiated spermatogonia is a strictly organized and programmed process requiring…”
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    Flavonoids as Therapeutic Compounds Targeting Key Proteins Involved in Alzheimer’s Disease by Baptista, Filipa I, Henriques, Ana G, Silva, Artur M. S, Wiltfang, Jens, da Cruz e Silva, Odete A. B

    Published in ACS chemical neuroscience (19-02-2014)
    “…Alzheimer’s disease is characterized by pathological aggregation of protein tau and amyloid-β peptides, both of which are considered to be toxic to neurons…”
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    APP Binds to the EGFR Ligands HB-EGF and EGF, Acting Synergistically with EGF to Promote ERK Signaling and Neuritogenesis by da Rocha, Joana F., Bastos, Luísa, Domingues, Sara C., Bento, Ana R., Konietzko, Uwe, da Cruz e Silva, Odete A. B., Vieira, Sandra I.

    Published in Molecular neurobiology (01-02-2021)
    “…The amyloid precursor protein (APP) is a transmembrane glycoprotein central to Alzheimer’s disease (AD) with functions in brain development and plasticity,…”
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    Not so pseudo: the evolutionary history of protein phosphatase 1 regulatory subunit 2 and related pseudogenes by Korrodi-Gregório, Luís, Abrantes, Joana, Muller, Thorsten, Melo-Ferreira, José, Marcus, Katrin, da Cruz e Silva, Odete A B, Fardilha, Margarida, Esteves, Pedro J

    Published in BMC evolutionary biology (06-11-2013)
    “…Pseudogenes are traditionally considered "dead" genes, therefore lacking biological functions. This view has however been challenged during the last decade…”
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    Editorial: Digital health and neuroscience: Recent history, current trends, and future developments by Pais-Vieira, Miguel, Ramakrishnan, Arjun, Rocon, Eduardo, Lebedev, Mikhail, Cruz-e-Silva, Odete A. B. da

    Published in Frontiers in integrative neuroscience (14-11-2022)
    “…According to the Food and Drug Administration (FDA)1, digital health is composed of the subfields of mobile health, health information technology, wearable…”
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    Diagnostic and therapeutic potential of exosomes in Alzheimer’s disease by Soares Martins, Tânia, Trindade, Dário, Vaz, Margarida, Campelo, Inês, Almeida, Martim, Trigo, Guilherme, da Cruz e Silva, Odete A. B., Henriques, Ana Gabriela

    Published in Journal of neurochemistry (01-01-2021)
    “…Exosomes are small extracellular vesicles released by almost all cell types in physiological and pathological conditions. The exosomal potential to unravel…”
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    Identification and characterization of the BRI2 interactome in the brain by Martins, Filipa, Marafona, Ana M., Pereira, Cátia D., Müller, Thorsten, Loosse, Christina, Kolbe, Katharina, da Cruz e Silva, Odete A. B., Rebelo, Sandra

    Published in Scientific reports (23-02-2018)
    “…BRI family proteins are ubiquitous type II transmembrane proteins but BRI2 is highly expressed in some neuronal tissues. Possible BRI2 functions include…”
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    Nuclear Accumulation of LAP1:TRF2 Complex during DNA Damage Response Uncovers a Novel Role for LAP1 by Pereira, Cátia D, Martins, Filipa, Santos, Mariana, Müeller, Thorsten, da Cruz E Silva, Odete A B, Rebelo, Sandra

    Published in Cells (Basel, Switzerland) (29-07-2020)
    “…Lamina-associated polypeptide 1 (LAP1) is a nuclear envelope (NE) protein whose function remains poorly characterized. In a recent LAP1 protein interactome…”
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    NMR metabolomics to study the metabolic response of human osteoblasts to non‐poled and poled poly (L‐lactic) acid by Araújo, Rita, Carneiro, Tatiana J., Marinho, Paula, Costa, Marisa Maltez, Roque, Ana, Cruz e Silva, Odete A. B., Fernandes, Maria Helena, Vilarinho, Paula M., Gil, Ana M.

    Published in Magnetic resonance in chemistry (01-11-2019)
    “…Untargeted nuclear magnetic resonance (NMR) metabolomics was employed, for the first time to our knowledge, to characterize the metabolome of human osteoblast…”
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    Protein phosphatase 1 and its complexes in carcinogenesis by Figueiredo, Joao, da Cruz E Silva, Odete A B, Fardilha, Margarida

    Published in Current cancer drug targets (01-01-2014)
    “…Understanding the molecular mechanisms and the signaling pathways that underlie the pathology of cancer progression is crucial for the development of novel…”
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    Identification and characterization of a neuronal enriched novel transcript encoding the previously described p60Fe65 isoform by Domingues, Sara Catarina, Henriques, Ana Gabriela, Fardilha, Margarida, da Cruz e Silva, Edgar F., da Cruz e Silva, Odete A.B.

    Published in Journal of neurochemistry (01-12-2011)
    “…J. Neurochem. (2011) 119, 1086–1098. Fe65 is a multimodular adaptor protein that interacts with the cytosolic domain of the β‐amyloid precursor protein (APP),…”
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