Nasopharyngeal colonization and penicillin resistance among pneumococcal strains: a worldwide 2004 update

Nasopharyngeal colonization and penicillin resistance among pneumococcal strains: a worldwide 2004 update

Surveillance of nasopharyngeal pneumococcus has proven to be a valuable tool for the monitoring of antibiotic resistance. We reviewed the latest information on colonization rate and penicillin resistance by making a MEDLINE search, using the terms "nasopharyngeal carriage" and "Strept...

Full description

Saved in:
Bibliographic Details
Published in:The Brazilian journal of infectious diseases Vol. 10; no. 4; pp. 293 - 303
Main Authors: Cardozo, Déa M, Nascimento-Carvalho, Cristiana M C, Souza, Fabiane R, Silva, Nívea M S
Format: Journal Article
Language:English
Published: Brazil Brazilian Society of Infectious Diseases 01-08-2006
Elsevier
Subjects:
Anti-Bacterial Agents - pharmacology
Carrier State - epidemiology
Carrier State - microbiology
Child
Child, Preschool
Global Health
Humans
INFECTIOUS DISEASES
Microbial Sensitivity Tests
nasopharyngeal carriage
Nasopharynx - microbiology
Penicillin Resistance
Streptococcus pneumoniae
Streptococcus pneumoniae - drug effects
Streptococcus pneumoniae - isolation & purification
penicillin resistance
nasopharyngeal carriage
Streptococcus pneumoniae
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Surveillance of nasopharyngeal pneumococcus has proven to be a valuable tool for the monitoring of antibiotic resistance. We reviewed the latest information on colonization rate and penicillin resistance by making a MEDLINE search, using the terms "nasopharyngeal carriage" and "Streptococcus pneumoniae". Out of 225 articles found, data from 109 recent publications (89% from 1996-2003) were analyzed. Data were reported from 41 countries of six continents. Individuals under the age of five (64.3%) or 10 years (85.7%) were enrolled, including children attending day-care centers (32.1%) or orphanages (3.6%), and healthy individuals (78.6%) or sick patients (43.6%); biological samples were collected mainly by nasopharyngeal swabs (89.3%). The highest colonization rates were reported from Africa (85-87.2%), where several authors did not find high rates of penicillin resistance. On the other hand, studies conducted in North and Central America reported high-level penicillin resistance at rates of approximately 20-30%. Great variation in the rates of pneumococcal colonization and penicillin resistance were observed within regions or continents. There were also considerable differences in similar populations located in different areas of the same country. Data regarding pneumococcal colonization and penicillin resistance are not available from most countries. We also examined the use of antibiotics to treat pneumococcal infections.
Bibliography:ObjectType-Article-2
SourceType-Scholarly Journals-1
ObjectType-Feature-3
content type line 23
ObjectType-Review-1
ISSN:1413-8670
1678-4391
DOI:10.1590/S1413-86702006000400015