Search Results - "Silva, Matheus Molina"

Revealing Temozolomide Resistance Mechanisms via Genome-Wide CRISPR Libraries by Rocha, Clarissa Ribeiro Reily, Reily Rocha, Alexandre, Molina Silva, Matheus, Rodrigues Gomes, Luciana, Teatin Latancia, Marcela, Andrade Tomaz, Marina, de Souza, Izadora, Karolynne Seregni Monteiro, Linda, Menck, Carlos Frederico Martins

“…Glioblastoma is a severe type of brain tumor with a poor prognosis and few therapy options. Temozolomide (TMZ) is one of these options, however, with limited…”
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Melanopsin (Opn4) is an oncogene in cutaneous melanoma by de Assis, Leonardo Vinícius Monteiro, Lacerda, José Thalles, Moraes, Maria Nathália, Domínguez-Amorocho, Omar Alberto, Kinker, Gabriela Sarti, Mendes, Davi, Silva, Matheus Molina, Menck, Carlos Frederico Martins, Câmara, Niels Olsen Saraiva, Castrucci, Ana Maria de Lauro

“…The search for new therapeutical targets for cutaneous melanoma and other cancers is an ongoing task. We expanded this knowledge by evaluating whether opsins,…”
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DNA repair pathways and cisplatin resistance: an intimate relationship by Rocha, Clarissa Ribeiro Reily, Silva, Matheus Molina, Quinet, Annabel, Cabral-Neto, Januario Bispo, Menck, Carlos Frederico Martins

“…The main goal of chemotherapeutic drugs is to induce massive cell death in tumors. Cisplatin is an antitumor drug widely used to treat several types of cancer…”
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The balance between NRF2/GSH antioxidant mediated pathway and DNA repair modulates cisplatin resistance in lung cancer cells by Silva, Matheus Molina, Rocha, Clarissa Ribeiro Reily, Kinker, Gabriela Sarti, Pelegrini, Alessandra Luiza, Menck, Carlos Frederico Martins

“…Lung cancer patients face a dismal prognosis mainly due to the low efficacy of current available treatments. Cisplatin is the first-line chemotherapy treatment…”
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Polymerase iota plays a key role during translesion synthesis of UV‐induced lesions in the absence of polymerase eta by Martins, Davi Jardim, Singh, Jenny Kaur, Jahjah, Tiya, Vessoni, Alexandre Teixeira, Leandro, Giovana da Silva, Silva, Matheus Molina, Biard, Denis Serge François, Quinet, Annabel, Menck, Carlos Frederico Martins

“…Xeroderma pigmentosum (XP) variant cells are deficient in the translesion synthesis (TLS) DNA polymerase Polη (eta). This protein contributes to DNA damage…”
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Loss of Melanopsin (OPN4) Leads to a Faster Cell Cycle Progression and Growth in Murine Melanocytes by de Assis, Leonardo Vinícius Monteiro, Moraes, Maria Nathália, Mendes, Davi, Silva, Matheus Molina, Menck, Carlos Frederico Martins, Castrucci, Ana Maria de Lauro

“…Skin melanocytes harbor a complex photosensitive system comprised of opsins, which were shown, in recent years, to display light- and thermo-independent…”
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Active immunization combined with cisplatin confers enhanced therapeutic protection and prevents relapses of HPV-induced tumors at different anatomical sites by Porchia, Bruna Felício Milazzotto Maldonado, Aps, Luana Raposo de Melo Moraes, Moreno, Ana Carolina Ramos, da Silva, Jamile Ramos, Silva, Mariângela de Oliveira, Sales, Natiely Silva, Alves, Rubens Prince Dos Santos, Rocha, Clarissa Ribeiro Reily, Silva, Matheus Molina, Rodrigues, Karine Bitencourt, Barros, Tácita Borges, Pagni, Roberta Liberato, Souza, Patrícia da Cruz, Diniz, Mariana de Oliveira, Ferreira, Luís Carlos de Souza

“…The active immunotherapy concept relies on the use of vaccines that are capable of inducing antitumor immunity, reversion of the suppressive immunological…”
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Melanopsin mediates UVA-dependent modulation of proliferation, pigmentation, apoptosis, and molecular clock in normal and malignant melanocytes by de Assis, Leonardo Vinícius Monteiro, Mendes, Davi, Silva, Matheus Molina, Kinker, Gabriela Sarti, Pereira-Lima, Isabella, Moraes, Maria Nathália, Menck, Carlos Frederico Martins, Castrucci, Ana Maria de Lauro

“…Cutaneous melanocytes and melanoma cells express several opsins, of which melanopsin (OPN4) detects temperature and UVA radiation. To evaluate the interaction…”
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Abstract 5360: Temozolomide-resistant glioblastoma cells are collaterally sensitive to ferroptosis through NRF2 high expression by de Souza, Izadora, Monteiro, Linda Karolynne, Guedes, Camila Banca, Latancia, Marcela, Andrade, Marina Tomaz, Silva, Matheus Molina, Contieri, Bruna, Ribeiro, Bruna Felício Milazzotto, Lazarini, Mariana, Gomes, Luciana, Rocha, Clarissa

“…Abstract Glioblastoma patients have a poor prognosis with a low median survival rate mainly due to temozolomide (TMZ) resistance. NRF2 is an important…”
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