Search Results - "Silva, Mariana Hugo"

Continuous Microfluidic Antisolvent Crystallization as a Bottom-Up Solution for the Development of Long-Acting Injectable Formulations by Nandi, Snehashis, Verstrepen, Laura, Hugo Silva, Mariana, Padrela, Luis, Tajber, Lidia, Collas, Alain

“…A bottom-up approach was investigated to produce long-acting injectable (LAI) suspension-based formulations to overcome specific limitations of top-down…”
Get full text

Osmolality of Excipients for Parenteral Formulation Measured by Freezing Point Depression and Vapor Pressure – A Comparative Analysis by Hugo Silva, Mariana, Hudson, Sarah P., Tajber, Lidia, Garin, Matthieu, Dong, Wenyu, Khamiakova, Tatsiana, Holm, René

“…Purpose To investigate the difference in methods to determine the osmolality in solutions of stabilizers used for long-acting injectable suspensions. Methods…”
Get full text

Impact of Excipients and Seeding on the Solid-State Form Transformation of Indomethacin during Liquid Antisolvent Precipitation by Hugo Silva, Mariana, Kumar, Ajay, Hodnett, Benjamin K., Tajber, Lidia, Holm, René, Hudson, Sarah P.

“…Long-acting injectables are a unique drug formulation strategy, providing a slow and sustained release of active pharmaceutical ingredients (APIs). In this…”
Get full text

Stabilization of blood for long-term storage can affect antibody-based recognition of cell surface markers by Silva, Mariana Hugo, Lepzien, Rico, Ols, Sebastian, Dahlberg, Benita, Grunewald, Johan, Loré, Karin, Smed-Sörensen, Anna, Correia-Neves, Margarida, Empadinhas, Nuno, Färnert, Anna, Källenius, Gunilla, Sundling, Christopher

“…Whole-blood fixation provides a rapid and simplified method for cell preservation compared to isolation of peripheral blood mononuclear cells (PBMCs). This can…”
Get full text