Search Results - "Silva, Mariana Ferreira"
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Role of TLR2/MyD88 in the production of specific IgM and IgG antibodies during the immunization of mice against Neospora caninum
Published in Vaccine (29-09-2022)“…Neospora caninum is a parasite relevant to the veterinary field. Innate and adaptive responses against N. caninum induce effector mechanisms that limit…”
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Minimal PU.1 reduction induces a preleukemic state and promotes development of acute myeloid leukemia
Published in Nature medicine (01-10-2015)“…Minimal reduction of PU.1 in mice is sufficient to elicit a preleukemic state that, when combined with a DNA mismatch repair defect, results in progression to…”
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3
Quality assurance systems: enemies or allies of innovation in higher education institutions?
Published in Quality assurance in education (06-01-2022)“…Purpose This study aims to examine the extant literature to analyze the relationship between quality assurance (QA) and innovation in the higher education…”
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4
TP53 mutations and RNA-binding protein MUSASHI-2 drive resistance to PRMT5-targeted therapy in B-cell lymphoma
Published in Nature communications (27-09-2022)“…To identify drivers of sensitivity and resistance to Protein Arginine Methyltransferase 5 (PRMT5) inhibition, we perform a genome-wide CRISPR/Cas9 screen. We…”
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Prevalence of Cannabis use among students at a public university in Bahia: comparison between repeated surveys
Published in Mundo da saúde (1995) (01-01-2020)“…The aim of this study was to compare the prevalence of Cannabis use between two repeated surveys among university students at a public higher education…”
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6
Stem cell mutations can be detected in myeloma patients years before onset of secondary leukemias
Published in Blood advances (10-12-2019)“…Therapy-related acute myeloid leukemia and myelodysplastic syndromes (t-AML/t-MDS) are secondary hematologic malignancies associated with poor prognosis,…”
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Formation of silk fibroin hydrogel and evaluation of its drug release profile
Published in Journal of applied polymer science (15-04-2015)“…ABSTRACT Silk hydrogels are interesting materials to be used as matrix in controlled drug delivery devices. However, methods to accelerate fibroin gelation and…”
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8
Identification and Validation of Toxoplasma gondii Mitoribosomal Large Subunit Components
Published in Microorganisms (Basel) (21-04-2022)“…Mitochondrial ribosomes are fundamental to mitochondrial function, and thus survival, of nearly all eukaryotes. Despite their common ancestry, mitoribosomes…”
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Phase II Study of the ALK5 Inhibitor Galunisertib in Very Low-, Low-, and Intermediate-Risk Myelodysplastic Syndromes
Published in Clinical cancer research (01-12-2019)“…Overactivation of TGF-β signaling is observed in myelodysplastic syndromes (MDS) and is associated with dysplastic hematopoietic differentiation. Galunisertib,…”
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10
Danger under wheels: mammal roadkills in the threaten lowland Atlantic Forest in southeast Brazil
Published in Iheringia. Série zoologia (01-01-2023)“…ABSTRACT Understanding the ecological impacts of roads on mammals requires periodic monitoring of roads, and identification of both temporal and spatial…”
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Tumor-targeted nanoparticles improve the therapeutic index of BCL2 and MCL1 dual inhibition
Published in Blood (15-04-2021)“…Cancer and normal cells use multiple antiapoptotic BCL2 proteins to prevent cell death. Therapeutic targeting of multiple BCL2 family proteins enhances tumor…”
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12
Synthetic lethality of drug-induced polyploidy and BCL-2 inhibition in lymphoma
Published in Nature communications (18-03-2023)“…Spontaneous whole genome duplication and the adaptive mutations that disrupt genome integrity checkpoints are infrequent events in B cell lymphomas. This…”
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13
Technologies and Mental Health in University Students: An Unhealthy Combination
Published in International Archives of Otorhinolaryngology (01-04-2023)“…Abstract Introduction The exposure of medical students to a full-time schedule that includes classes, extracurricular activities, patients' lives…”
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14
TNF-TNFR1 Signaling Enhances the Protection Against Neospora caninum Infection
Published in Frontiers in cellular and infection microbiology (07-01-2022)“…is a protozoan associated with abortions in ruminants and neuromuscular disease in dogs. Classically, the immune response against apicomplexan parasites is…”
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15
Contemporary (2019) prevalence of cardiovascular disease in adults with type 2 diabetes in Brazil: the cross-sectional CAPTURE study
Published in Diabetology and metabolic syndrome (10-01-2022)“…Type 2 diabetes (T2D) is a known risk factor for cardiovascular disease (CVD), and CVD is a major cause of mortality in patients with T2D. The CAPTURE study…”
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16
ASN007 is a selective ERK1/2 inhibitor with preferential activity against RAS-and RAF-mutant tumors
Published in Cell reports. Medicine (20-07-2021)“…Inhibition of the extracellular signal-regulated kinases ERK1 and ERK2 (ERK1/2) offers a promising therapeutic strategy in cancers harboring activated…”
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17
Biological and Enzymatic Characterization of Proteases from Crude Venom of the Ant Odontomachus bauri
Published in Toxins (30-11-2015)“…Hymenoptera venoms constitute an interesting source of natural toxins that may lead to the development of novel therapeutic agents. The present study…”
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Analysis of the reallocation of time spent sitting, sleeping, and performing physical activities under negative self-rated heath of university students
Published in Mundo da saúde (1995) (01-01-2022)“…The aim of this study was to examine the effect of isotemporal substitution of physical activity, sedentary, and sleep time in relation to negative self-rated…”
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Psychosocial aspects of living with diabetes mellitus in promoting self-care
Published in Rev. RENE (21-02-2016)“…Objective: to understand the psychosocial aspects of living with diabetes mellitus. Methods: a study qualitative,made with 16 patients with diabetes mellitus…”
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Insomnia and excessive daytime sleepiness in medical students: consequences of the use of technologies?
Published in Sleep science (São Paulo, SP ) (2022)“…Objective To analyze the relation among insomnia, excessive daytime sleepiness and the excessive use of technologies in medical students. Methods The study was…”
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