Search Results - "Silva, Marcia Cristina Freitas"
-
1
From Molecules to Behavior in Long-Term Inorganic Mercury Intoxication: Unraveling Proteomic Features in Cerebellar Neurodegeneration of Rats
Published in International journal of molecular sciences (22-12-2021)“…Mercury is a severe environmental pollutant with neurotoxic effects, especially when exposed for long periods. Although there are several evidences regarding…”
Get full text
Journal Article -
2
Methylmercury Causes Neurodegeneration and Downregulation of Myelin Basic Protein in the Spinal Cord of Offspring Rats after Maternal Exposure
Published in International journal of molecular sciences (29-03-2022)“…Methylmercury (MeHg) is one of the most dangerous toxic pollutants spread throughout the earth. Chronic MeHg intoxication by contaminated food ingestion is the…”
Get full text
Journal Article -
3
Repeated Cycles of Binge-Like Ethanol Intake in Adolescent Female Rats Induce Motor Function Impairment and Oxidative Damage in Motor Cortex and Liver, but Not in Blood
Published in Oxidative medicine and cellular longevity (01-01-2018)“…Moderate ethanol consumption (MEC) is increasing among women. Alcohol exposure usually starts in adolescence and tends to continue until adulthood. We aimed to…”
Get full text
Journal Article -
4
Effects of inorganic mercury exposure in the alveolar bone of rats: an approach of qualitative and morphological aspects
Published in PeerJ (San Francisco, CA) (26-01-2022)“…In comparison to organic mercury (MeHg), the environmental inorganic mercury (IHg) can be found in some skin-lightening cosmestics were considered "harmless"…”
Get full text
Journal Article -
5
Deciphering the Global Proteomic Profile Involved in Methylmercury-Induced Cerebellar Neurodegeneration and Motor Dysfunction in Adult Rats
Published in Toxics (Basel) (01-09-2022)“…Mercury is a ubiquitous pollutant in the environment with potential neurotoxic effects. Several populations are susceptible to mercurial exposure, especially…”
Get full text
Journal Article -
6
Chronic intoxication by methylmercury leads to oxidative damage and cell death in salivary glands of rats
Published in Metallomics (01-12-2017)“…Methylmercury (MeHg) is one of the most toxic species of mercury, causing several systemic damages; however, its effect on the salivary glands has rarely been…”
Get full text
Journal Article -
7
Hippocampal Dysfunction Provoked by Mercury Chloride Exposure: Evaluation of Cognitive Impairment, Oxidative Stress, Tissue Injury and Nature of Cell Death
Published in Oxidative medicine and cellular longevity (01-01-2018)“…Mercury (Hg) is a highly toxic metal, which can be found in its inorganic form in the environment. This form presents lower liposolubility and lower absorption…”
Get full text
Journal Article -
8
Hypoglycemic and hypolipidemic effects of Lippia origanoides Kunth in diabetic rats
Published in Food science & nutrition (01-07-2024)“…Diabetes mellitus is a metabolic disorder commonly associated with atherosclerosis. Plants with therapeutic potential, such as Lippia origanoides Kunth, emerge…”
Get full text
Journal Article -
9
In utero and lactational exposure to methylmercury elicits physical-chemical and morphological damages in the alveolar bone of offspring rats: The first toxicological findings
Published in Chemosphere (Oxford) (01-12-2022)“…Methylmercury (MeHg) is the most common organic form of mercury (Hg) that humans are exposed and is considered an environmental pollutant. Several populations…”
Get full text
Journal Article -
10
Spinal cord neurodegeneration after inorganic mercury long-term exposure in adult rats: Ultrastructural, proteomic and biochemical damages associated with reduced neuronal density
Published in Ecotoxicology and environmental safety (15-03-2020)“…Mercury chloride (HgCl2) is a chemical pollutant widely found in the environment. This form of mercury is able to promote several damages to the Central…”
Get full text
Journal Article -
11
Chronic methylmercury exposure causes spinal cord impairment: Proteomic modulation and oxidative stress
Published in Food and chemical toxicology (01-12-2020)“…Methylmercury (MeHg) is considered by the World Health Organization (WHO) as one of the chemicals of greatest public health concern. Although central nervous…”
Get full text
Journal Article -
12
Proteomic approach underlying the hippocampal neurodegeneration caused by low doses of methylmercury after long-term exposure in adult rats
Published in Metallomics (20-02-2019)“…Methylmercury (MeHg) is an important toxicant that causes cognitive dysfunctions in humans. This study aimed to investigate the proteomic and biochemical…”
Get full text
Journal Article -
13
Methylmercury Intoxication Promotes Metallothionein Response and Cell Damage in Salivary Glands of Rats
Published in Biological trace element research (01-09-2018)“…Environmental and occupational mercury exposure is considered a major public health issue. Despite being well known that MeHg exposure causes adverse effects…”
Get full text
Journal Article -
14
Oxidative Biochemistry Disbalance and Changes on Proteomic Profile in Salivary Glands of Rats Induced by Chronic Exposure to Methylmercury
Published in Oxidative medicine and cellular longevity (01-01-2017)“…Methylmercury (MeHg) is one of the most toxic mercury species, which can cause many systemic damages, but little is known about its effect in the salivary…”
Get full text
Journal Article -
15
Imaging Microstructural Damage and Alveolar Bone Loss in Rats Systemically Exposed to Methylmercury: First Experimental Evidence
Published in Biological trace element research (01-10-2021)“…The alveolar bone is an important mineralized structure of the periodontal support apparatus, and information about the methylmercury (MeHg) effects on the…”
Get full text
Journal Article -
16
COVID-19 in the Eastern Brazilian Amazon: Incidence, Clinical Management, and Mortality by Social Determinants of Health, Symptomatology, and Comorbidities in the Xingu Health Region
Published in International journal of environmental research and public health (06-03-2023)“…This study aims to investigate the relationship between social determinants of health (SDH), incidence, and mortality to verify which sociodemographic factors,…”
Get full text
Journal Article -
17
Methylmercury exposure during prenatal and postnatal neurodevelopment promotes oxidative stress associated with motor and cognitive damages in rats: an environmental-experimental toxicology study
Published in Toxicology reports (2022)“…The environmental contamination by methylmercury (MeHg) is a major concern for public health. The effects of MeHg in the central nervous system (CNS) of adult…”
Get full text
Journal Article -
18
Neurochemical dysfunction in motor cortex and hippocampus impairs the behavioral performance of rats chronically exposed to inorganic mercury
Published in Journal of trace elements in medicine and biology (01-03-2019)“…Chronic exposure to mercury chloride (HgCl2) has been shown to promote oxidative stress and cell death in the central nervous system of adult rats displaying…”
Get full text
Journal Article -
19
Behavioural, electrocorticographic, and electromyographic alterations induced by Nerium oleander ethanolic extract: Anticonvulsant therapeutics assessment
Published in Neurotoxicology (Park Forest South) (01-05-2020)“…•This study characterizes the seizurogenic potential of Nerium oleander extract.•N. oleander extract induced myorelaxation followed by neuronal…”
Get full text
Journal Article -
20
Low doses of methylmercury exposure during adulthood in rats display oxidative stress, neurodegeneration in the motor cortex and lead to impairment of motor skills
Published in Journal of trace elements in medicine and biology (01-01-2019)“…Despite the vast distribution among tissues, the central nervous system (CNS) represents the main target of methylmercury (MeHg) toxicity. However, few studies…”
Get full text
Journal Article