Search Results - "Silva, Malan"

Glutamylation Regulates Transport, Specializes Function, and Sculpts the Structure of Cilia by O’Hagan, Robert, Silva, Malan, Nguyen, Ken C.Q., Zhang, Winnie, Bellotti, Sebastian, Ramadan, Yasmin H., Hall, David H., Barr, Maureen M.

“…Ciliary microtubules (MTs) are extensively decorated with post-translational modifications (PTMs), such as glutamylation of tubulin tails. PTMs and tubulin…”
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Ciliary Rab28 and the BBSome negatively regulate extracellular vesicle shedding by Akella, Jyothi S, Carter, Stephen P, Nguyen, Ken, Tsiropoulou, Sofia, Moran, Ailis L, Silva, Malan, Rizvi, Fatima, Kennedy, Breandan N, Hall, David H, Barr, Maureen M, Blacque, Oliver E

“…Cilia both receive and send information, the latter in the form of extracellular vesicles (EVs). EVs are nano-communication devices that influence cell,…”
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CaV1 and CaV2 calcium channels mediate the release of distinct pools of synaptic vesicles by Mueller, Brian D, Merrill, Sean A, Watanabe, Shigeki, Liu, Ping, Niu, Longgang, Singh, Anish, Maldonado-Catala, Pablo, Cherry, Alex, Rich, Matthew S, Silva, Malan, Maricq, Andres Villu, Wang, Zhao-Wen, Jorgensen, Erik M

“…Activation of voltage-gated calcium channels at presynaptic terminals leads to local increases in calcium and the fusion of synaptic vesicles containing…”
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Cell-Specific Transcriptional Profiling of Ciliated Sensory Neurons Reveals Regulators of Behavior and Extracellular Vesicle Biogenesis by Wang, Juan, Kaletsky, Rachel, Silva, Malan, Williams, April, Haas, Leonard A., Androwski, Rebecca J., Landis, Jessica N., Patrick, Cory, Rashid, Alina, Santiago-Martinez, Dianaliz, Gravato-Nobre, Maria, Hodgkin, Jonathan, Hall, David H., Murphy, Coleen T., Barr, Maureen M.

“…Cilia and extracellular vesicles (EVs) are signaling organelles [1]. Cilia act as cellular sensory antennae, with defects resulting in human ciliopathies…”
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Hydrodynamic Effects of Mastigonemes in the Cryptophyte Chilomonas paramecium by Sanchez Arias, Ludivine, Webb, Branden, Samsami, Kiarash, Nikolova, Linda, Silva, Malan, Fu, Henry C.

“…Many swimming protists travel by actuating whip-like flagella to generate thrust. While many organisms’ flagella have been observed to have hair-like…”
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The Tubulin Deglutamylase CCPP-1 Regulates the Function and Stability of Sensory Cilia in C. elegans by O'Hagan, Robert, Piasecki, Brian P., Silva, Malan, Phirke, Prasad, Nguyen, Ken C.Q., Hall, David H., Swoboda, Peter, Barr, Maureen M.

“…Posttranslational modifications (PTMs) such as acetylation, detyrosination, and polyglutamylation have long been considered markers of stable microtubules and…”
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Tomography gives a new dimension to an ancient organelle by Silva, Malan, Barr, Maureen M

“…Advances in sample preparation and electron microscopy have allowed the structure of cilia to be explored at an unprecedented level of detail…”
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The nphp-2 and arl-13 genetic modules interact to regulate ciliogenesis and ciliary microtubule patterning in C. elegans by Warburton-Pitt, Simon R F, Silva, Malan, Nguyen, Ken C Q, Hall, David H, Barr, Maureen M

“…Cilia are microtubule-based cellular organelles that mediate signal transduction. Cilia are organized into several structurally and functionally distinct…”
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Sensory cilia act as a specialized venue for regulated extracellular vesicle biogenesis and signaling by Wang, Juan, Nikonorova, Inna A., Silva, Malan, Walsh, Jonathon D., Tilton, Peter E., Gu, Amanda, Akella, Jyothi S., Barr, Maureen M.

“…Ciliary extracellular vesicle (EV) shedding is evolutionarily conserved. In Chlamydomonas and C. elegans, ciliary EVs act as signaling devices.1–3 In cultured…”
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C. elegans Ciliated Sensory Neurons Release Extracellular Vesicles that Function in Animal Communication by Wang, Juan, Silva, Malan, Haas, Leonard A., Morsci, Natalia S., Nguyen, Ken C.Q., Hall, David H., Barr, Maureen M.

“…Cells release extracellular vesicles (ECVs) that play important roles in intercellular communication and may mediate a broad range of physiological and…”
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MCTP-1 modulates neurotransmitter release in C. elegans by Téllez-Arreola, José Luis, Silva, Malan, Martínez-Torres, Ataúlfo

“…Multiple C2 and Transmembrane Domain Proteins (MCTPs) are putative calcium sensors. Proteins that contain C2 domains play essential roles in membrane…”
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Quinoin, type 1 ribosome inactivating protein alters SARS-CoV-2 viral replication organelle restricting viral replication and spread by Tiano, Sofia Maria Luigia, Landi, Nicola, Marano, Valentina, Ragucci, Sara, Bianco, Gennaro, Cacchiarelli, Davide, Swuec, Paolo, Silva, Malan, De Cegli, Rossella, Sacco, Francesca, Di Maro, Antimo, Cortese, Mirko

“…SARS-CoV-2 pandemic clearly demonstrated the lack of preparation against novel and emerging viral diseases. This prompted an enormous effort to identify…”
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Serialized on-grid lift-in sectioning for tomography (SOLIST) enables a biopsy at the nanoscale by Nguyen, Ho Thuy Dung, Perone, Gaia, Klena, Nikolai, Vazzana, Roberta, Kaluthantrige Don, Flaminia, Silva, Malan, Sorrentino, Simona, Swuec, Paolo, Leroux, Frederic, Kalebic, Nereo, Coscia, Francesca, Erdmann, Philipp S.

“…Cryo-focused ion beam milling has substantially advanced our understanding of molecular processes by opening windows into cells. However, applying this…”
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Plasma membrane tension regulates eisosome structure and function by Appadurai, Daniel, Gay, Lincoln, Moharir, Akshay, Lang, Michael J, Duncan, Mara C, Schmidt, Oliver, Teis, David, Vu, Thien N, Silva, Malan, Jorgensen, Erik M, Babst, Markus

“…Eisosomes are membrane furrows at the cell surface of yeast that have been shown to function in two seemingly distinct pathways, membrane stress response and…”
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Cell-Specific α-Tubulin Isotype Regulates Ciliary Microtubule Ultrastructure, Intraflagellar Transport, and Extracellular Vesicle Biology by Silva, Malan, Morsci, Natalia, Nguyen, Ken C.Q., Rizvi, Anza, Rongo, Christopher, Hall, David H., Barr, Maureen M.

“…Cilia are found on most non-dividing cells in the human body and, when faulty, cause a wide range of pathologies called ciliopathies. Ciliary specialization in…”
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Myristoylated CIL-7 regulates ciliary extracellular vesicle biogenesis by Maguire, Julie E, Silva, Malan, Nguyen, Ken C Q, Hellen, Elizabeth, Kern, Andrew D, Hall, David H, Barr, Maureen M

“…The cilium both releases and binds to extracellular vesicles (EVs). EVs may be used by cells as a form of intercellular communication and mediate a broad range…”
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Cilia and Extracellular Vesicles are signaling organelles by Barr, Maureen, Wang, Juan, Silva, Malan, Hall, David, Maguire, Julie

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Cell type‐specific structural plasticity of the ciliary transition zone in C. elegans by Akella, Jyothi S., Silva, Malan, Morsci, Natalia S., Nguyen, Ken C., Rice, William J., Hall, David H., Barr, Maureen M.

“…Background information The current consensus on cilia development posits that the ciliary transition zone (TZ) is formed via extension of nine centrosomal…”
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The nphp-2 and arl-13 Genetic Modules Interact to Regulate Ciliogenesis and Ciliary Microtubule Patterning in C. elegans: e1004866 by Warburton-Pitt, Simon RF, Silva, Malan, Nguyen, Ken CQ, Hall, David H, Barr, Maureen M

“…Cilia are microtubule-based cellular organelles that mediate signal transduction. Cilia are organized into several structurally and functionally distinct…”
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The minus‐end actin capping protein, UNC‐94/tropomodulin, regulates development of the Caenorhabditis elegans intestine by Cox‐Paulson, Elisabeth, Cannataro, Vincent, Gallagher, Thomas, Hoffman, Corey, Mantione, Gary, Mcintosh, Matthew, Silva, Malan, Vissichelli, Nicole, Walker, Rachel, Simske, Jeffrey, Ono, Shoichiro, Hoops, Harold

“…Background: Tropomodulins are actin‐capping proteins that regulate the stability of the slow‐growing, minus‐ends of actin filaments. The C. elegans…”
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