Search Results - "Silva, Luciane Sussuchi"

Whole blood mRNA expression-based targets to discriminate active tuberculosis from latent infection and other pulmonary diseases by Petrilli, Jéssica D., Araújo, Luana E., da Silva, Luciane Sussuchi, Laus, Ana Carolina, Müller, Igor, Reis, Rui Manuel, Netto, Eduardo Martins, Riley, Lee W., Arruda, Sérgio, Queiroz, Adriano

“…Current diagnostic tests for tuberculosis (TB) are not able to predict reactivation disease progression from latent TB infection (LTBI). The main barrier to…”
Get full text

Comprehensive microRNA expression analysis of pediatric gonadal germ cell tumors: unveiling novel biomarkers and signatures by Santarosa Vieira, Ana Glenda, Silva, Luciane Sussuchi, Albino da Silva, Eduardo Caetano, Laus, Ana Carolina, Faria, Thaíssa Maria Veiga, Helvoort Lengert, André, Martins, Gisele Eiras, Oliveira, Marco Antônio, Reis, Rui Manuel, Lopes, Luiz Fernando, Pinto, Mariana Tomazini

“…microRNAs (miRNAs) are small endogenous noncoding RNAs, and alterations in their expression may contribute to oncogenesis. Discovering a unique miRNA pattern…”
Get full text

Cancer immune profiling unveils biomarkers, immunological pathways, and cell type score associated with glioblastoma patients’ survival by Moreno, Daniel Antunes, da Silva, Luciane Sussuchi, Gomes, Isabella, Leal, Letícia Ferro, Berardinelli, Gustavo Noriz, Gonçalves, Gisele Melo, Pereira, Caio Augusto, Santana, Iara Viana Vidigal, Matsushita, Marcus de Medeiros, Bhat, Krishna, Lawler, Sean, Reis, Rui Manuel

“…Introduction: Glioblastoma (GBM), isocitrate dehydrogenase (IDH) wild-type (IDHwt), and grade 4 astrocytomas, IDH mutant (IDHmut), are the most common and…”
Get full text

Comprehensive Molecular Landscape of Cetuximab Resistance in Head and Neck Cancer Cell Lines by Gomes, Izabela N F, da Silva-Oliveira, Renato J, da Silva, Luciane Sussuchi, Martinho, Olga, Evangelista, Adriane F, van Helvoort Lengert, André, Leal, Letícia Ferro, Silva, Viviane Aline Oliveira, Dos Santos, Stéphanie Piancenti, Nascimento, Flávia Caroline, Lopes Carvalho, André, Reis, Rui Manuel

“…Cetuximab is the sole anti-EGFR monoclonal antibody that is FDA approved to treat head and neck squamous cell carcinoma (HNSCC). However, no predictive…”
Get full text

Loss of 5'-Methylthioadenosine Phosphorylase (MTAP) is Frequent in High-Grade Gliomas; Nevertheless, it is Not Associated with Higher Tumor Aggressiveness by Menezes, Weder Pereira de, Silva, Viviane Aline Oliveira, Gomes, Izabela Natália Faria, Rosa, Marcela Nunes, Spina, Maria Luisa Corcoll, Carloni, Adriana Cruvinel, Alves, Ana Laura Vieira, Melendez, Matias, Almeida, Gisele Caravina, Silva, Luciane Sussuchi da, Clara, Carlos, da Cunha, Isabela Werneck, Hajj, Glaucia Noeli Maroso, Jones, Chris, Bidinotto, Lucas Tadeu, Reis, Rui Manuel

“…The 5'-methylthioadenosine phosphorylase (MTAP) gene is located in the chromosomal region 9p21. deletion is a frequent event in a wide variety of human…”
Get full text

Potential New Therapeutic Approaches for Cisplatin-Resistant Testicular Germ Cell Tumors by Lengert, André van Helvoort, Pereira, Leticia do Nascimento Braga, Cabral, Eduardo Ramos Martins, Gomes, Izabela Natalia Faria, Jesus, Lais Machado de, Gonçalves, Maria Fernanda Santiago, Rocha, Aline Oliveira da, Tassinari, Tiago Alexandre, Silva, Luciane Sussuchi da, Laus, Ana Carolina, Vidal, Daniel Onofre, Pinto, Mariana Tomazini, Reis, Rui Manuel, Lopes, Luiz Fernando

“…BACKGROUNDTesticular germ cell tumors (TGCTs), a group of heterogeneous neoplasms, are the most frequent tumors of teenagers and young men, with the incidence…”
Get full text

The digital expression profile of BMP7, CDKN2C, HIST1H3G, and PKMYT1 genes improves high‐grade cervical lesion detection in liquid‐based cytology by Causin, Rhafaela Lima, Sussuchi da Silva, Luciane, Leal, Leticia Ferro, Possati‐Resende, Júlio César, Evangelista, Adriane Feijó, Matsushita, Graziela Macedo, Scapulatempo‐Neto, Cristovam, Tavares Guerreiro Fregnani, José Humberto, Antônio de Oliveira, Marco, Musselwhite, Laura W., Chiquitelli Marques, Márcia Maria, Reis, Rui Manuel

“…Background Some studies reported that differential gene expression could be used as a biomarker for high‐grade cervical lesion identification. The aim was to…”
Get full text

Low MGMT digital expression is associated with a better outcome of IDH1 wildtype glioblastomas treated with temozolomide by Gomes, Isabella, Moreno, Daniel Antunes, dos Reis, Mariana Bisarro, da Silva, Luciane Sussuchi, Leal, Letícia Ferro, Gonçalves, Gisele Melo, Pereira, Caio Augusto, Oliveira, Marco Antônio, de Medeiros Matsushita, Marcus, Reis, Rui Manuel

“…Introduction Glioblastoma (GBM) is the deadliest primary brain tumor. The standard treatment consists of surgery, radiotherapy, and temozolomide (TMZ). TMZ…”
Get full text

Single nCounter assay for prediction of MYCN amplification and molecular classification of medulloblastomas: a multicentric study by Moreno, Daniel Antunes, da Silva, Luciane Sussuchi, Zanon, Maicon Fernando, Bonatelli, Murilo, de Paula, Flávia Escremim, de Medeiros Matsushita, Marcus, Teixeira, Gustavo Ramos, Santana, Iara Viana Vidigal, Saggioro, Fabiano, Neder, Luciano, Stavale, João N., Malheiros, Suzana Maria Fleury, Lima, Matheus, Hajj, Glaucia Noeli Maroso, Garcia-Rivello, Hernan, Christiansen, Silvia, Nunes, Susana, da Costa, Maria João Gil, Soares, Maria José, Pinheiro, Jorge, Junior, Carlos Almeida, Mançano, Bruna Minniti, Reis, Rui Manuel

“…Purpose Medulloblastoma is the most frequent pediatric malignant brain tumor, and is divided into four main subgroups: WNT, SHH, group 3, and group 4. MYCN…”
Get full text

Establishment and molecular characterization of HCB-541, a novel and aggressive human cutaneous squamous cell carcinoma cell line by Laus, Ana Carolina, Gomes, Izabela Natalia Faria, da Silva, Aline Larissa Virginio, da Silva, Luciane Sussuchi, Milan, Mirella Baroni, AparecidaTeixeira, Silvia, Martin, Ana Carolina Baptista Moreno, do Nascimento Braga Pereira, Letícia, de Carvalho, Carlos Eduardo Barbosa, Crovador, Camila Souza, de Paula, Flávia Escremin, Nascimento, Flávia Caroline, de Freitas, Helder Teixeira, de Lima Vazquez, Vinicius, Reis, Rui Manuel, da Silva-Oliveira, Renato José

“…Cutaneous squamous cell carcinoma (cSCC) is a common type of skin cancer that can result in significant morbidity, although it is usually well-managed and…”
Get full text

miR-99a-5p as a biomarker for lymph node metastasis prediction in oral squamous cell carcinoma patients by Cousseau, Cristiane Pereira Vargas, Sorroche, Bruna Pereira, de Jesus Teixeira, Renan, de Carvalho, Ana Carolina, Melendez, Matias Eliseo, de Castro Capuzzo, Renato, Laus, Ana Carolina, da Silva, Luciane Sussuchi, de Menezes, Nei Soares, Carvalho, André Lopes, Arantes, Lidia Maria Rebolho Batista

“…Metastatic lymph node involvement influences therapy decisions and serves as a prognostic indicator in oral squamous cell carcinoma (OSCC). However, many…”
Get full text

Efficacy of Combined Use of Everolimus and Second-Generation Pan-EGRF Inhibitors in KRAS Mutant Non-Small Cell Lung Cancer Cell Lines by da Silva-Oliveira, Renato José, Gomes, Izabela Natalia Faria, da Silva, Luciane Sussuchi, Lengert, André van Helvoort, Laus, Ana Carolina, Melendez, Matias Eliseo, Munari, Carla Carolina, Cury, Fernanda de Paula, Longato, Giovanna Barbarini, Reis, Rui Manuel

“…Background: EGFR mutations are present in approximately 15−50% of non-small cell lung cancer (NSCLC), which are predictive of anti-EGFR therapies. At variance,…”
Get full text

Cell-free DNA promotes malignant transformation in non-tumor cells by Souza, Aline Gomes de, Bastos, Victor Alexandre F., Fujimura, Patricia Tieme, Ferreira, Izabella Cristina C., Leal, Letícia Ferro, da Silva, Luciane Sussuchi, Laus, Ana Carolina, Reis, Rui Manuel, Martins, Mario Machado, Santos, Paula Souza, Corrêa, Natássia C. Resende, Marangoni, Karina, Thomé, Carolina Hassibe, Colli, Leandro Machado, Goulart, Luiz Ricardo, Goulart, Vivian Alonso

“…Cell-free DNA is present in different biological fluids and when released by tumor cells may contribute to pro-tumor events such as malignant transformation of…”
Get full text

Potential Implications for Designing Drugs Against the Brown Spider Venom Phospholipase‐D by Chaves‐Moreira, Daniele, de Moraes, Fábio Rogério, Caruso, Ícaro Putinhon, Chaim, Olga Meiri, Senff‐Ribeiro, Andrea, Ullah, Anwar, da Silva, Luciane Sussuchi, Chahine, Jorge, Arni, Raghuvir K., Veiga, Silvio Sanches

“…ABSTRACT Loxoscelism refers to the clinical symptoms that develop after brown spider bites. Brown spider venoms contain several phospholipase‐D isoforms, which…”
Get full text

Gene expression profiles (GEPs) of immuno-oncologic pathways as predictors of response to checkpoint inhibitors in advanced NSCLC by De Marchi, Pedro, Leal, Leticia Ferro, da Silva, Luciane Sussuchi, Cavagna, Rodrigo de Oliveira, da Silva, Flavio Augusto Ferreira, da Silva, Vinicius Duval, da Silva, Eduardo CA, Saito, Augusto O., de Lima, Vladmir C. Cordeiro, Reis, Rui Manuel

“…BACKGROUNDImmune checkpoint inhibitors (ICIs) revolutionized non-small-cell lung cancer (NSCLC) treatment. However, improving patients' selection for this…”
Get full text

Early Emergence and Dispersal of Delta SARS-CoV-2 Lineage AY.99.2 in Brazil by Romano, Camila Malta, de Oliveira, Cristina Mendes, da Silva, Luciane Sussuchi, Levi, José Eduardo

“…The year of 2021 was marked by the emergence and dispersal of a number of SARS-CoV-2 lineages, resulting in the “third wave” of COVID-19 in several countries…”
Get full text

A 4-Gene Signature Associated With Recurrence in Low- and Intermediate-Risk Endometrial Cancer by de Andrade, Diocésio Alves Pinto, da Silva, Luciane Sussuchi, Laus, Ana Carolina, de Lima, Marcos Alves, Berardinelli, Gustavo Nóriz, da Silva, Vinicius Duval, Matsushita, Graziela de Macedo, Bonatelli, Murilo, da Silva, Aline Larissa Virginio, Evangelista, Adriane Feijó, Carvalho, Jesus Paula, Reis, Rui Manuel, Dos Reis, Ricardo

“…The molecular profile of endometrial cancer has become an important tool in determining patient prognosis and their optimal adjuvant treatment. In addition to…”
Get full text

HMGB1 Expression Levels Correlate with Response to Immunotherapy in Non-Small Cell Lung Cancer by González-Cao, Maria, Cai, Xueting, Bracht, Jilian Wilhelmina Paulina, Han, Xuan, Yang, Yang, Pedraz-Valdunciel, Carlos, Morán, Teresa, García-Corbacho, Javier, Aguilar, Andrés, Bernabé, Reyes, De Marchi, Pedro, Sussuchi da Silva, Luciane, Leal, Leticia Ferro, Reis, Rui Manuel, Codony-Servat, Jordi, Jantus-Lewintre, Eloisa, Molina-Vila, Miguel Angel, Cao, Peng, Rosell, Rafael

“…High-mobility group box 1 protein (HMGB1) is subject to exportin 1 (XPO1)-dependent nuclear export, and it is involved in functions implicated in resistance to…”
Get full text

Simultaneous analysis of ALK, RET, and ROS1 gene fusions by NanoString in Brazilian lung adenocarcinoma patients by Novaes, Lázaro Antonio Campanha, Sussuchi da Silva, Luciane, De Marchi, Pedro, Cavagna, Rodrigo de Oliveira, de Paula, Flavia Escremim, Zanon, Maicon Fernando, Evangelista, Adriane Feijó, Albino da Silva, Eduardo Caetano, Duval da Silva, Vinícius, Leal, Letícia Ferro, Reis, Rui Manuel

Get full text

LungTS: A new gene expression signature for prediction of response to checkpoint inhibitors in non-small cell lung cancer by De Marchi, Pedro, Ferro Leal, Leticia, da Silva, Luciane Sussuchi, de Oliveira Cavagna, Rodrigo, Ferreira da Silva, Flavio Augusto, da Silva, Vinicius Duval, da Silva, Eduardo CA, Saito, Augusto Obuti, Aguado, Cristina, Bracht, Jill, Gonzalez-Cao, Maria, Giménez-Capitán, Ana, Pedraz, Carlos, Sá, Daniella Dias Silva, Molina Vila, Miguel Angel, Cordeiro De Lima, Vladmir Claudio, Reis, Rui Manuel

“…e21143 Background: Immune checkpoint inhibitors (ICIs) are associated with durable antitumor activity in advanced non-small cell lung cancer (NSCLC), however,…”
Get full text