Search Results - "Silva, Kathryn"
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Activation of cannabinoid receptors by the pentacyclic triterpene α,β-amyrin inhibits inflammatory and neuropathic persistent pain in mice
Published in Pain (Amsterdam) (01-08-2011)“…The pentacyclic triterpene α,β-amyrin binds to CB1 and CB2 receptors and reduces inflammation and hyperalgesia in 2 models of persistent pain in mice. In this…”
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2
Cholecalciferol counteracts depressive-like behavior and oxidative stress induced by repeated corticosterone treatment in mice
Published in European journal of pharmacology (15-08-2018)“…Depression is one of the most frequent neuropsychiatric diseases in the western world and its physiological causes are not yet fully understood. Since the…”
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3
Plant derived alkaloid (−)-cassine induces anti-inflammatory and anti-hyperalgesics effects in both acute and chronic inflammatory and neuropathic pain models
Published in Neuropharmacology (01-02-2012)“…Natural products have been revealed as relevant sources of therapeutic agents including those for the management of pain states. In this study, the…”
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4
Nanoemulsion as a carrier to improve the topical anti-inflammatory activity of stem bark extract of Rapanea ferruginea
Published in International journal of nanomedicine (01-01-2016)“…The aim of this study was to develop nanoemulsion containing soft extract of stem bark of to improve the topical delivery and anti-inflammatory activity. The…”
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5
Cannabinoid agonists inhibit neuropathic pain induced by brachial plexus avulsion in mice by affecting glial cells and MAP kinases
Published in PloS one (13-09-2011)“…Many studies have shown the antinociceptive effects of cannabinoid (CB) agonists in different models of pain. Herein, we have investigated their relevance in…”
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6
Biological and Toxicological Evaluation of N-(4methyl-phenyl)-4-methylphthalimide on Bone Cancer in Mice
Published in Anti-cancer agents in medicinal chemistry (01-01-2019)“…It was recently demonstrated that the phthalimide N-(4-methyl-phenyl)-4- methylphthalimide (MPMPH-1) has important effects against acute and chronic pain in…”
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7
IRF4 controls the positioning of mature B cells in the lymphoid microenvironments by regulating NOTCH2 expression and activity
Published in The Journal of experimental medicine (16-12-2013)“…The transcription factor interferon regulatory factor-4 (IRF4) is expressed in B cells at most developmental stages. In antigen-activated B cells, IRF4…”
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From popular use to pharmacological validation: A study of the anti-inflammatory, anti-nociceptive and healing effects of Chenopodium ambrosioides extract
Published in Journal of ethnopharmacology (09-01-2013)“…Chenopodium ambrosioides (Amarantaceae) is an annual or perennial plant popularly known as ‘erva de Santa Maria’, ‘mastruço’ and ‘erva-do-formigueiro’. This…”
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9
Involvement of phosphoinositide 3-kinase γ in the neuro-inflammatory response and cognitive impairments induced by β-amyloid 1–40 peptide in mice
Published in Brain, behavior, and immunity (01-03-2010)“…Abstract Alzheimer disease (AD) is the most common form of dementia in the elderly, and the neuro-pathological hallmarks of AD include neurofibrillary tangles…”
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10
The kinin B1 and B2 receptors and TNFR1/p55 axis on neuropathic pain in the mouse brachial plexus
Published in Inflammopharmacology (01-06-2019)“…Tumour necrosis factor (TNF) and kinins have been associated with neuropathic pain-like behaviour in numerous animal models. However, the way that they…”
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11
Euphol, a tetracyclic triterpene produces antinociceptive effects in inflammatory and neuropathic pain: The involvement of cannabinoid system
Published in Neuropharmacology (01-09-2012)“…Persistent pains associated with inflammatory and neuropathic states are prevalent and debilitating diseases, which still remain without a safe and adequate…”
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12
Retinal pigment epithelial cells use a MerTK-dependent mechanism to limit the phagocytic particle binding activity of αvβ5 integrin
Published in Biology of the cell (01-06-2012)“…Background information αvβ5 integrin and Mer tyrosine kinase (MerTK) receptors reside at the apical surface of the retinal pigment epithelium (RPE) in the eye…”
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13
Anti-inflammatory and anti-hyperalgesic evaluation of the condiment laurel (Litsea guatemalensis Mez.) and its chemical composition
Published in Food chemistry (15-06-2012)“…► Litsea guatemalensis (LG), native to Central America, is used as a food condiment. ► Pinocembrin and scopoletin were isolated from DCM fraction of LG. ►…”
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14
Topical anti-inflammatory activity of semisolid containing standardized Aleurites moluccana L. Willd (Euphorbiaceae) leaves extract
Published in Journal of ethnopharmacology (15-09-2015)“…Aleurites moluccana is a medicinal plant popularly used to treat pain, fever, asthma, hepatitis, gastric ulcer and inflammatory process in general. Recently,…”
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15
Neuropharmacological and acute toxicological evaluation of ethanolic extract of Allamanda cathartica L. flowers and plumieride
Published in Regulatory toxicology and pharmacology (01-12-2017)“…Psychiatric diseases affect more than 350 million people all over the world, and medicinal plants have been considered the basis for pharmacological research…”
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The kinin B 1 and B 2 receptors and TNFR1/p55 axis on neuropathic pain in the mouse brachial plexus
Published in Inflammopharmacology (01-06-2019)“…Tumour necrosis factor (TNF) and kinins have been associated with neuropathic pain-like behaviour in numerous animal models. However, the way that they…”
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17
The Antihypersensitive and Antiinflammatory Activities of a Benzofuranone Derivative in Different Experimental Models in Mice: The Importance of the Protein Kinase C Pathway
Published in Anesthesia and analgesia (01-10-2014)“…Benzofuranone (BF1) was synthesized and its effects evaluated on mechanical hypersensitivity and paw edema models induced by different agents and on…”
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Correction to: The kinin B1 and B2 receptors and TNFR1/p55 axis on neuropathic pain in the mouse brachial plexus
Published in Inflammopharmacology (01-06-2019)“…Unfortunately, the Fig. 7 was wrongly downloaded in the original publication…”
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Do internal medicine interns practice etiquette-based communication? A critical look at the inpatient encounter
Published in Journal of hospital medicine (01-11-2013)“…Etiquette‐based communication may improve the inpatient experience but is not universally practiced. We sought to determine the extent to which internal…”
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Variability in hand hygiene practices among internal medicine interns
Published in American journal of infection control (01-11-2013)“…Hand hygiene compliance remains suboptimal among physicians despite quality improvement efforts. We observed hand hygiene compliance among 29 medicine interns…”
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