Search Results - "Silva, Jaqueline Azevêdo"
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Upregulation of FOXP3 may act on immunological misbalance in Turner syndrome
Published in Scandinavian journal of immunology (01-03-2023)“…Turner syndrome (TS) presents a characteristic immune imbalance among patients. As the X chromosome‐linked FOXP3 gene is a powerful immune regulator, in this…”
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Differential distribution in vitamin D receptor gene variants and expression profile in Northeast Brazil influences upon active pulmonary tuberculosis
Published in Molecular biology reports (01-09-2020)“…Tuberculosis is an infectious disease with variable outcomes. This variability is due to host immune capacity in containing the infection process initiated by…”
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Polymorphisms and expression of inflammasome genes are associated with the development and severity of rheumatoid arthritis in Brazilian patients
Published in Inflammation research (01-03-2018)“…Objective In the present study, we analyzed the possible association of inflammasome gene variants and expression to rheumatoid arthritis (RA)’s development…”
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DC-SIGN polymorphisms are associated to type 1 diabetes mellitus
Published in Immunobiology (1979) (01-11-2014)“…Abstract Type I diabetes mellitus (T1DM) is an autoimmune disorder featured by raised glucoses levels. It has been hypothesised that raised glucose levels in…”
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Differential distribution of vitamin D receptor (VDR) gene variants and its expression in systemic lupus erythematosus
Published in International journal of immunogenetics (01-06-2022)“…Systemic lupus erythematosus (SLE) is a multifactorial autoimmune disorder that displays an important genetic background. Vitamin D3 (VD3) through its receptor…”
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T-cell specific upregulation of Sema4A as risk factor for autoimmunity in systemic lupus erythematosus and rheumatoid arthritis
Published in Autoimmunity (Chur, Switzerland) (17-02-2020)“…The aim of the present study was to evaluate the impact of SEMA4A genetic variants on expression of sema4A protein and its relation to autoimmunity development…”
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Vitamin D receptor polymorphisms and expression profile in rheumatoid arthritis brazilian patients
Published in Molecular biology reports (01-01-2016)“…Rheumatoid arthritis (RA) is an autoimmune disease characterized by chronic inflammation and important joint commitment, being the most common systemic…”
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Vitamin D receptor (VDR) gene polymorphisms and age onset in type 1 diabetes mellitus
Published in Autoimmunity (Chur, Switzerland) (01-09-2013)“…Abstract Vitamin D receptor is a mediator of immune responses through the action of vitamin D, which is capable of regulate the insulin secretion by the…”
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Differential expression of the inflammasome complex genes in systemic lupus erythematosus
Published in Immunogenetics (New York) (01-05-2020)“…Systemic lupus erythematosus (SLE) is a complex autoimmune disorder involving heterogeneous clinical manifestations and numerous susceptibility genes. Several…”
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Vitamin D receptor gene polymorphisms influence on clinical profile and bone mineral density at different skeletal sites in postmenopausal osteoporotic women
Published in International journal of immunogenetics (01-04-2023)“…Bone remodeling is marked by bone synthesis and absorption balance, and any altered dynamic in this process leads to osteoporosis (OP). The interaction of…”
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CTLA-4 gene polymorphisms are associated with obesity in Turner Syndrome
Published in Genetics and molecular biology (01-10-2018)“…Turner syndrome (TS) is characterized by a set of clinical conditions, including autoimmune/inflammatory diseases and infectious conditions, that can…”
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Is there an Inflammation Role for MYD88 in Rheumatoid Arthritis?
Published in Inflammation (01-06-2021)“…Rheumatoid arthritis (RA) is an autoimmune and inflammatory disease with strong genetic influence, especially upon immune response components. Several…”
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Caveolin-1 (CAV-1) up regulation in metabolic syndrome: all roads leading to the same end
Published in Molecular biology reports (01-11-2020)“…Metabolic syndrome (MS) is a set of clinical conditions such as insulin resistance, hyperglycemia, systemic arterial hypertension (SAH), dyslipidemia, obesity…”
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Postmenopausal Osteoporosis reference genes for qPCR expression assays
Published in Scientific reports (11-11-2019)“…Osteoporosis (OP) is a multifactorial disease influenced by genetic factors in more than half of the cases. In spite of the efforts to clarify the relationship…”
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Commiphora leptophloeos Phytochemical and Antimicrobial Characterization
Published in Frontiers in microbiology (24-01-2017)“…is a plant specie usually known for its medicinal purposes in local communities in Northeast Brazil. In order to evaluate its therapeutic potential, we aimed…”
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Ficolin Gene Polymorphisms in Systemic Lupus Erythematosus and Rheumatoid Arthritis
Published in Annals of human genetics (01-01-2016)“…Summary Systemic lupus erythemathosus (SLE) and rheumatoid arthritis (RA) are complex autoimmune diseases characterized by an immune balance breakdown and by…”
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Vitamin D and estrogen steroid hormones and their immunogenetic roles in Infectious respiratory (TB and COVID-19) diseases
Published in Genetics and molecular biology (2023)“…The role of steroid hormones against infectious diseases has been extensively studied. From immunomodulatory action to direct inhibition of microorganism…”
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Expression profile of inflammasome genes in individuals with Down syndrome
Published in Genetics and molecular biology (01-01-2024)“…Down syndrome (DS), affecting 1 in 700 live births, is the most prevalent chromosomal disorder among newborns. Recognizable by classical clinical features,…”
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Pathogen recognition pathway gene variants and inflammasome sensors gene expression in tuberculosis patients under treatment
Published in Molecular biology reports (01-12-2024)“…Background Several epidemiological studies have suggested that genetic variations in encoding pattern recognition receptors (PRRs) genes such as Toll Like…”
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