Search Results - "Silva, Jamile Ramos da"
-
1
Establishment of an Antiplasmodial Vaccine Based on PfRH5-Encoding RNA Replicons Stabilized by Cationic Liposomes
Published in Pharmaceutics (01-04-2023)“…Nucleic acid-based vaccines have been studied for the past four decades, but the approval of the first messenger RNA (mRNA) vaccines during the COVID-19…”
Get full text
Journal Article -
2
A Multi-Targeting, Nucleoside-Modified mRNA Influenza Virus Vaccine Provides Broad Protection in Mice
Published in Molecular therapy (08-07-2020)“…Influenza viruses are respiratory pathogens of public health concern worldwide with up to 650,000 deaths occurring each year. Seasonal influenza virus vaccines…”
Get full text
Journal Article -
3
Single immunizations of self-amplifying or non-replicating mRNA-LNP vaccines control HPV-associated tumors in mice
Published in Science translational medicine (08-03-2023)“…As mRNA vaccines have proved to be very successful in battling the coronavirus disease 2019 (COVID-19) pandemic, this new modality has attracted widespread…”
Get more information
Journal Article -
4
Interleukin-6 and indoleamine-2,3-dioxygenase as potential adjuvant targets for Papillomavirus-related tumors immunotherapy
Published in Frontiers in immunology (03-11-2022)“…High-risk Human papillomavirus (HPV) infections represent an important public health issue. Nearly all cervical malignancies are associated with HPV, and a…”
Get full text
Journal Article -
5
Nano-multilamellar lipid vesicles loaded with a recombinant form of the chikungunya virus E2 protein improve the induction of virus-neutralizing antibodies
Published in Nanomedicine (01-10-2021)“…Chikungunya virus (CHIKV) is responsible for a self-limited illness that can evolve into long-lasting painful joint inflammation. In this study, we report a…”
Get full text
Journal Article -
6
Active immunization combined with cisplatin confers enhanced therapeutic protection and prevents relapses of HPV-induced tumors at different anatomical sites
Published in International journal of biological sciences (2022)“…The active immunotherapy concept relies on the use of vaccines that are capable of inducing antitumor immunity, reversion of the suppressive immunological…”
Get full text
Journal Article -
7
A therapeutic DNA vaccine and gemcitabine act synergistically to eradicate HPV-associated tumors in a preclinical model
Published in Oncoimmunology (01-01-2021)“…Although active immunotherapies are effective strategies to induce activation of CD8 + T cells, advanced stage tumors require further improvements for…”
Get full text
Journal Article -
8
Abstract A65: In vivo neutralization of IL-10 enhances the antitumor effects of a therapeutic vaccine against HPV-associated tumor
Published in Clinical cancer research (01-01-2018)“…Although experimental therapeutic vaccines against HPV-induced tumors are capable of activating systemic E6 and E7-specific CD8+ T cells and inducing high…”
Get full text
Journal Article -
9
Modulating APOBEC expression enhances DNA vaccine immunogenicity
Published in Immunology and cell biology (01-11-2015)“…DNA vaccines have failed to induce satisfactory immune responses in humans. Several mechanisms of double‐stranded DNA (dsDNA) sensing have been described, and…”
Get full text
Journal Article