Search Results - "Silva, Izabella T"

In vitro and in vivo antitumor activity of a novel semisynthetic derivative of cucurbitacin B by Silva, Izabella T, Carvalho, Annelise, Lang, Karen L, Dudek, Sabine E, Masemann, Dörthe, Durán, Fernando J, Caro, Miguel S B, Rapp, Ulf R, Wixler, Viktor, Schenkel, Eloir P, Simões, Cláudia M O, Ludwig, Stephan

“…Lung cancer is the most deadly type of cancer in humans, with non-small-cell lung cancer (NSCLC) being the most frequent and aggressive type of lung cancer…”
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Synthesis and cytotoxicity evaluation of glycosidic derivatives of lawsone against breast cancer cell lines by Ottoni, Flaviano M., Gomes, Eliza R., Pádua, Rodrigo M., Oliveira, Mônica C., Silva, Izabella T., Alves, Ricardo J.

“…[Display omitted] •Glycosylation of lawsone enhances its antitumor activity.•Glucosyl triazole of lawsone displays submicromolar IC50 against SKBR-3 breast…”
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Cytotoxic activity of semi-synthetic derivatives of elatol and isoobtusol by Lang, Karen L, Silva, Izabella T, Zimmermann, Lara A, Lhullier, Cíntia, Mañalich Arana, Maria V, Palermo, Jorge A, Falkenberg, Miriam, Simões, Cláudia M O, Schenkel, Eloir P, Durán, Fernando J

“…In the present study, the in vitro cytotoxic effects of six semi-synthetic derivatives of elatol (1) and isoobtusol (2) were investigated. Chemical…”
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Multivariate SAR and QSAR of cucurbitacin derivatives as cytotoxic compounds in a human lung adenocarcinoma cell line by Lang, Karen L., Silva, Izabella T., Machado, Vanessa R., Zimmermann, Lara A., Caro, Miguel S.B., Simões, Cláudia M.O., Schenkel, Eloir P., Durán, Fernando J., Bernardes, Lílian S.C., de Melo, Eduardo B.

“…•Cucurbitacins are natural products known for their several pharmacological properties.•A data set with 43 cucurbitacins derivatives was used for a SAR/QSAR…”
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New cytotoxic cucurbitacins from Wilbrandia ebracteata Cogn by Lang, Karen L, da Rosa Guimarães, Tatiana, Rocha Machado, Vanessa, Zimmermann, Lara A, Silva, Izabella T, Teixeira, Marina R, Durán, Fernando J, Palermo, Jorge A, Simões, Cláudia M O, Caro, Miguel S B, Schenkel, Eloir P

“…Chemical investigation of the roots of Wilbrandia ebracteata Cogn. (Cucurbitaceae) led to the isolation of two new (1- 2) and four known (3- 6) cucurbitacins…”
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Abstract 1089: Cardiac glycosides affect miRNA expression profiles in renal cell carcinoma cell lines by Nolte, Elke, Wach, Sven, da Silva, Izabella T., Ekici, Arif, Müller-Uri, Frieder, Kreis, Wolfgang, Vera-Gonzales, Julio, Wullich, Bernd, Taubert, Helge, Lai, Xin

“…Abstract Background: Renal Cell Carcinoma (RCC) is the ninth most common cancer worldwide, with about 338,000 new cases diagnosed in 2012. Especially…”
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In Vitro and In Vivo Antitumor Activity of a Novel Semisynthetic Derivative of Cucurbitacin B: e0117794 by Silva, Izabella T, Carvalho, Annelise, Lang, Karen L, Dudek, Sabine E, Masemann, Dorthe, Duran, Fernando J, Caro, Miguel SB, Rapp, Ulf R, Wixler, Viktor, Schenkel, Eloir P

“…Lung cancer is the most deadly type of cancer in humans, with non-small-cell lung cancer (NSCLC) being the most frequent and aggressive type of lung cancer…”
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Antiherpes screening of marine organisms from Colombian Caribbean Sea by Silva, Izabella T., Caon, Thiago, Lückemeyer, Débora D., Ramos, Freddy A., Tello, Edisson, Arévalo-Ferro, Catalina, Schenkel, Eloir P., Duque, Carmenza, Simões, Cláudia M. O.

“…The exploration of marine environment represents a promising strategy in the search for new active antiviral compounds. The isolation and characterization of…”
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