Search Results - "Silva, Iran A."

Extracellular‐Matrix‐Reinforced Bioinks for 3D Bioprinting Human Tissue by De Santis, Martina M., Alsafadi, Hani N., Tas, Sinem, Bölükbas, Deniz A., Prithiviraj, Sujeethkumar, Da Silva, Iran A. N., Mittendorfer, Margareta, Ota, Chiharu, Stegmayr, John, Daoud, Fatima, Königshoff, Melanie, Swärd, Karl, Wood, Jeffery A., Tassieri, Manlio, Bourgine, Paul E., Lindstedt, Sandra, Mohlin, Sofie, Wagner, Darcy E.

“…Recent advances in 3D bioprinting allow for generating intricate structures with dimensions relevant for human tissue, but suitable bioinks for producing…”
Get full text

Reduction of primary graft dysfunction using cytokine adsorption during organ preservation and after lung transplantation by Ghaidan, Haider, Stenlo, Martin, Niroomand, Anna, Mittendorfer, Margareta, Hirdman, Gabriel, Gvazava, Nika, Edström, Dag, Silva, Iran A. N., Broberg, Ellen, Hallgren, Oskar, Olm, Franziska, Wagner, Darcy E., Pierre, Leif, Hyllén, Snejana, Lindstedt, Sandra

“…Despite improvements, lung transplantation remains hampered by both a scarcity of donor organs and by mortality following primary graft dysfunction (PGD)…”
Get full text

The Effect of Gene Editing by CRISPR-Cas9 of miR-21 and the Indirect Target MMP9 in Metastatic Prostate Cancer by Camargo, Juliana A, Viana, Nayara I, Pimenta, Ruan, Guimarães, Vanessa R, dos Santos, Gabriel A, Candido, Patrícia, Ghazarian, Vitória, Romão, Poliana, Silva, Iran A, Birbrair, Alexander, Srougi, Miguel, Nahas, William C, Leite, Kátia R, Trarbach, Ericka B, Reis, Sabrina T

“…Prostate cancer (PCa) has a high prevalence and represents an important health problem, with an increased risk of metastasis. With the advance of CRISPR-Cas9…”
Get full text

Intratumoral Restoration of miR-137 Plus Cholesterol Favors Homeostasis of the miR-137/Coactivator p160/AR Axis and Negatively Modulates Tumor Progression in Advanced Prostate Cancer by Pimenta, Ruan, Mioshi, Carolina Mie, Gonçalves, Guilherme L, Candido, Patrícia, Camargo, Juliana A, Guimarães, Vanessa R, Chiovatto, Caroline, Ghazarian, Vitória, Romão, Poliana, da Silva, Karina Serafim, Dos Santos, Gabriel A, Silva, Iran A, Srougi, Miguel, Nahas, William C, Leite, Kátia R, Viana, Nayara I, Reis, Sabrina T

“…MicroRNAs (miRNAs) have gained a prominent role as biomarkers in prostate cancer (PCa). Our study aimed to evaluate the potential suppressive effect of miR-137…”
Get full text

Comprehensive study of gene and microRNA expression related to epithelial-mesenchymal transition in prostate cancer by Katz, Betina, Reis, Sabrina T, Viana, Nayara I, Morais, Denis R, Moura, Caio M, Dip, Nelson, Silva, Iran A, Iscaife, Alexandre, Srougi, Miguel, Leite, Katia R M

“…Prostate cancer is the most common cancer in men, and most patients have localized disease at the time of diagnosis. However, 4% already present with…”
Get full text

miR-618: possible control over TIMP-1 and its expression in localized prostate cancer by Ivanovic, Renato F, Viana, Nayara I, Morais, Denis R, Moura, Caio, Silva, Iran A, Leite, Katia R, Pontes-Junior, José, Nahas, William C, Srougi, Miguel, Reis, Sabrina T

“…The imbalance between the action of the tissue inhibitors of matrix metalloproteinases (TIMPs) and the matrix metalloproteinases (MMPs) is one component of…”
Get full text

miR-29b enhances prostate cancer cell invasion independently of MMP-2 expression by Ivanovic, Renato F, Viana, Nayara I, Morais, Denis R, Silva, Iran A, Leite, Katia R, Pontes-Junior, José, Inoue, Gustavo, Nahas, William C, Srougi, Miguel, Reis, Sabrina T

“…The ability to metastasize is one of the most important characteristics of neoplastic cells. An imbalance between the action of some matrix metalloproteinases…”
Get full text

Controlling RECK miR21 Promotes Tumor Cell Invasion and Is Related to Biochemical Recurrence in Prostate Cancer by Leite, Katia R M, Reis, Sabrina T, Viana, Nayara, Morais, Denis R, Moura, Caio M, Silva, Iran A, Pontes, Jr, José, Katz, Betina, Srougi, Miguel

“…The search for biomarkers to characterize prostate cancer aggressiveness has been the objective for the majority of researchers involved with the most…”
Get full text

BCG downregulates PD1 and PD-L1 expression in bladder cancer cells co-cultivated with peripheral blood mononuclear cells by Leite, Katia R. M., Morais, Denis Reis, Massoco, Cristina, Reis, Sabrina T., Viana, Nayara I., Silva, Iran A., Guimaraes, Vanessa, Pimenta, Ruan, Arantes, Gabriel, Srougi, Miguel, Nahas, Willian Carlos

“…PurposeBCG is the standard of care to treat high risk non-muscle invasive bladder cancer (NMIBC), reducing recurrence. PD-L1 is a ligand of the co-inhibitory…”
Get full text

MicroRNA 100: a context dependent miRNA in prostate cancer by Leite, Katia R.M., Morais, Denis R., Reis, Sabrina T., Viana, Nayara, Moura, Caio, Florez, Manuel Garcia, Silva, Iran A., Dip, Nelson, Srougi, Miguel

“…MicroRNAs are noncoding RNA molecules involved in the development and progression of tumors. We have found that miRNA-100 is underexpressed in metastatic…”
Get full text

The involvement of miR-100 in bladder urothelial carcinogenesis changing the expression levels of mRNA and proteins of genes related to cell proliferation, survival, apoptosis and chromosomal stability by Morais, Denis R, Reis, Sabrina T, Viana, Nayara, Piantino, Camila Berfort, Massoco, Cristina, Moura, Caio, Dip, Nelson, Silva, Iran A, Srougi, Miguel, Leite, Katia Rm

“…MicroRNAs (miRNA) are small non-coding RNAs that play an important role in the control of gene expression by inhibiting protein translation or promoting…”
Get full text

The role of micro RNAs let7c, 100 and 218 expression and their target RAS, C-MYC, BUB1, RB, SMARCA5, LAMB3 and Ki-67 in prostate cancer by Reis, Sabrina T., Timoszczuk, Luciana S., Pontes-Junior, José, Viana, Nayara, Silva, Iran A., Dip, Nelson, Srougi, Miguel, Leite, Katia R.M.

“…The aim of this study is to verify the expression of proteins that are controlled by miR-let7c, 100 and 218 using immunohistochemistry in tissue microarray…”
Get full text

Monitoring lung injury with particle flow rate in LPS‐ and COVID‐19‐induced ARDS by Stenlo, Martin, Silva, Iran A. N., Hyllén, Snejana, Bölükbas, Deniz A., Niroomand, Anna, Grins, Edgars, Ederoth, Per, Hallgren, Oskar, Pierre, Leif, Wagner, Darcy E., Lindstedt, Sandra

“…In severe acute respiratory distress syndrome (ARDS), extracorporeal membrane oxygenation (ECMO) is a life‐prolonging treatment, especially among COVID‐19…”
Get full text

The role of microRNAs 371 and 34a in androgen receptor control influencing prostate cancer behavior by Leite, Katia R.M., M.D., Ph.D, Morais, Denis Reis, M.Sc, Florez, Manuel Garcia, M.D, Reis, Sabrina T., Ph.D, Iscaife, Alexandre, M.D, Viana, Nayara, M.Sc, Moura, Caio M., M.Sc, Silva, Iran A., M.Sc, Katz, Betina S., M.D., Ph.D, Pontes, Jose, M.D., Ph.D, Nesrallah, Adriano, M.D., Ph.D, Srougi, Miguel, M.D., Ph.D

“…Abstract Background The molecular mechanisms involved in androgen receptor (AR) signaling pathways are not completely understood, and deregulation of microRNAs…”
Get full text

Micro RNA expression and prognosis in low-grade non-invasive urothelial carcinoma by Dip, Nelson, Reis, Sabrina T, Abe, Daniel K, Viana, Nayara I, Morais, Denis R, Moura, Caio M, Katz, Betina, Silva, Iran A, Srougi, Miguel, Leite, Katia R M

“…To analyze a possible correlation between a miRNA expression profile and important prognostic factors for pTa urothelial carcinomas (UC), including tumor size,…”
Get full text

Prima-1 induces apoptosis in bladder cancer cell lines by activating p53 by Piantino, Camila B., Reis, Sabrina T., Viana, Nayara I., Silva, Iran A., Morais, Denis R., Antunes, Alberto A., Dip, Nelson, Srougi, Miguel, Leite, Katia R.

“…Bladder cancer represents 3% of all carcinomas in the Brazilian population and ranks second in incidence among urological tumors, after prostate cancer. The…”
Get full text

Cholesterol Triggers Nuclear Co-Association of Androgen Receptor, p160 Steroid Coactivators, and p300/CBP-Associated Factor Leading to Androgenic Axis Transactivation in Castration-Resistant Prostate Cancer by Pimenta, Ruan, Camargo, Juliana A, Candido, Patrícia, Ghazarian, Vitória, Gonçalves, Guilherme L, Guimarães, Vanessa R, Romão, Poliana, Chiovatto, Caroline, Mioshi, Carolina M, Dos Santos, Gabriel A, Silva, Iran A, Birbrair, Alexander, Srougi, Miguel, Nahas, William C, Leite, Kátia R, Viana, Nayara I, Reis, Sabrina T

“…BACKGROUND/AIMS: Cholesterol modulates intratumoral androgenic signaling in prostate cancer; however, the molecular mechanisms underlying these changes in…”
Get full text

Overexpression of miR-17-5p may negatively impact p300/CBP factor-associated inflammation in a hypercholesterolemic advanced prostate cancer model by Pimenta, Ruan, Camargo, Juliana A., Gonçalves, Guilherme L., Ghazarian, Vitória, Candido, Patrícia, Guimarães, Vanessa R., Romão, Poliana, Chiovatto, Caroline, da Silva, Karina Serafim, dos Santos, Gabriel A., Silva, Iran A., Nahas, William C., Leite, Kátia R., Pessoa, Ana Flávia Marçal, Viana, Nayara I., Reis, Sabrina T.

“…Background Previously, we demonstrated that cholesterol triggers the increase in p300/CBP-associated factor (PCAF), targeted by miR-17-5p. The p300, IL-6,…”
Get full text

MiR-200c-3p expression may be associated with worsening of the clinical course of patients with COVID-19 by Pimenta, Ruan, Viana, Nayara I, Dos Santos, Gabriel A, Candido, Patrícia, Guimarães, Vanessa R, Romão, Poliana, Silva, Iran A, de Camargo, Juliana A, Hatanaka, Diná M, Queiroz, Paula G S, Teruya, Alexandre, Echenique, Leandro, Besen, Bruno A M P, Leite, Katia R M, Srougi, Victor, Srougi, Miguel, Reis, Sabrina T

“…COVID-19 represents a public health emergency, whose mechanism of which is not fully understood. It is speculated that microRNAs may play a crucial role in…”
Get full text

Phospholipase A2 expression in prostate cancer as a biomarker of good prognosis: A comprehensive study in patients with long follow-up by Recuero, Saulo da Cunha, Viana, Nayara I, Reis, Sabrina T, Mendes, Keith T, Talib, Leda L, Gattaz, Wagner F, Guimarães, Vanessa R, Silva, Iran A, Pimenta, Ruan C. P, Camargo, Juliana A, Nahas, Willian C, Srougi, Miguel, Leite, Katia R. M

“…Background: Phospholipase A2 (PLA2) is a large family of enzymes involved in the inflammatory process that catalyzes the hydrolysis of membrane phospholipids,…”
Get full text