Search Results - "Silva, Gustavo M"

Expanding Role of Ubiquitin in Translational Control by Dougherty, Shannon E, Maduka, Austin O, Inada, Toshifumi, Silva, Gustavo M

“…The eukaryotic proteome has to be precisely regulated at multiple levels of gene expression, from transcription, translation, and degradation of RNA and…”
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Recurrent Mutations of Chromatin-Remodeling Genes and Kinase Receptors in Pheochromocytomas and Paragangliomas by Toledo, Rodrigo A, Qin, Yuejuan, Cheng, Zi-Ming, Gao, Qing, Iwata, Shintaro, Silva, Gustavo M, Prasad, Manju L, Ocal, I Tolgay, Rao, Sarika, Aronin, Neil, Barontini, Marta, Bruder, Jan, Reddick, Robert L, Chen, Yidong, Aguiar, Ricardo C T, Dahia, Patricia L M

“…Pheochromocytomas and paragangliomas (PPGL) are genetically heterogeneous tumors of neural crest origin, but the molecular basis of most PPGLs is unknown. We…”
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The ubiquitin conjugase Rad6 mediates ribosome pausing during oxidative stress by Meydan, Sezen, Barros, Géssica C., Simões, Vanessa, Harley, Lana, Cizubu, Blanche K., Guydosh, Nicholas R., Silva, Gustavo M.

“…Oxidative stress causes K63-linked ubiquitination of ribosomes by the E2 ubiquitin conjugase Rad6. How Rad6-mediated ubiquitination of ribosomes affects…”
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Silicon, biological seed treatment and cutting reduce the intensity of leaf spot diseases affecting Lolium multiflorum by Victoria Arellano, Alfonso D., Furtado, Emanueli B., Holz, Tailine M., Pazdiora, Paulo C., Silva, Gustavo M., Del Ponte, Emerson M., Dallagnol, Leandro J.

“…Italian ryegrass is a major pasture crop cultivated mainly for feeding cattle in southern Brazil. The choice of crop is based on nutritional quality and the…”
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Associations between Movement Behaviours and Obesity Markers among Preschoolers Compliant and Non-Compliant with Sleep Duration: A Latent Profile Analysis by Souza, Alesandra A de, Mota, Jorge A P S, Silva, Gustavo M G da, Tassitano, Rafael M, Clark, Cain C T, Duncan, Michael J, Martins, Clarice M de L

“…This study identifies physical activity (PA) and sedentary behaviour (SB) clusters in preschoolers compliant (C) or non-compliant (NC) with sleep…”
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Deubiquitinating enzymes (DUBs): Regulation, homeostasis, and oxidative stress response by Snyder, Nathan A., Silva, Gustavo M.

“…Ubiquitin signaling is a conserved, widespread, and dynamic process in which protein substrates are rapidly modified by ubiquitin to impact protein activity,…”
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K63 polyubiquitination is a new modulator of the oxidative stress response by Silva, Gustavo M, Finley, Daniel, Vogel, Christine

“…Oxidative stress induces a number of cellular responses. Silva et al . uncover a peroxide-mediated K63-linked polyubiquitination pathway, and identify its…”
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Ubiquitin and the Control of Translation During Oxidative Stress by Silva, Gustavo M.

“…During exposure to environmental stresses, eukaryotic cells must reprogram gene expression at the transcriptional and translational levels in order to thrive…”
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Influence of HLA-DRB1 and HLA-DQB1 alleles on IgG antibody response to the P. vivax MSP-1, MSP-3α and MSP-9 in individuals from Brazilian endemic area by Lima-Junior, Josué C, Rodrigues-da-Silva, Rodrigo N, Banic, Dalma M, Jiang, Jianlin, Singh, Balwan, Fabrício-Silva, Gustavo M, Porto, Luís C S, Meyer, Esmeralda V S, Moreno, Alberto, Rodrigues, Maurício M, Barnwell, John W, Galinski, Mary R, de Oliveira-Ferreira, Joseli

“…The antibody response generated during malaria infections is of particular interest, since the production of specific IgG antibodies is required for…”
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Isoleucine 44 Hydrophobic Patch Controls Toxicity of Unanchored, Linear Ubiquitin Chains through NF-κB Signaling by Blount, Jessica R, Libohova, Kozeta, Silva, Gustavo M, Todi, Sokol V

“…Ubiquitination is a post-translational modification that regulates cellular processes by altering the interactions of proteins to which ubiquitin, a small…”
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Economic selection index in small rural dairy farms by Yokoo, Marcos Jun-Iti, Seno, Leonardo de Oliveira, Oliveira, Luiza Corrêa, Costa, Pedro U N da, Silva, Gustavo M da, Suñé, Renata W, Cardoso, Fernando Flores

“…This study aimed to calculate economic values (EVs) and economic selection indices for milk production systems in small rural properties. The traits 305-d milk…”
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Redox regulation of the proteasome via S-glutathionylation by Demasi, Marilene, Netto, Luis E S, Silva, Gustavo M, Hand, Adrian, de Oliveira, Cristiano L P, Bicev, Renata N, Gozzo, Fabio, Barros, Mario H, Leme, Janaina M M, Ohara, Erina

“…The proteasome is a multimeric and multicatalytic intracellular protease responsible for the degradation of proteins involved in cell cycle control, various…”
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Site-Specific K63 Ubiquitinomics Provides Insights into Translation Regulation under Stress by Back, Songhee, Gorman, Andrew W, Vogel, Christine, Silva, Gustavo M

“…During oxidative stress, K63-linked polyubiquitin chains modify a variety of proteins including ribosomes. Knowledge of the precise sites of K63 ubiquitin is…”
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The cysteine-rich protein thimet oligopeptidase as a model of the structural requirements for S-glutathiolation and oxidative oligomerization by Malvezzi, Alberto, Higa, Patrícia M, T-do Amaral, Antonia, Silva, Gustavo M, Gozzo, Fabio C, Ferro, Emer S, Castro, Leandro M, de Rezende, Leandro, Monteiro, Gisele, Demasi, Marilene

“…Thimet oligopeptidase (EP24.15) is a cysteine-rich metallopeptidase containing fifteen Cys residues and no intra-protein disulfide bonds. Previous work on this…”
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Role of glutaredoxin 2 and cytosolic thioredoxins in cysteinyl-based redox modification of the 20S proteasome by Silva, Gustavo M, Netto, Luis E.S, Discola, Karen F, Piassa-Filho, Gilberto M, Pimenta, Daniel C, Bárcena, José A, Demasi, Marilene

“…The yeast 20S proteasome is subject to sulfhydryl redox alterations, such as the oxidation of cysteine residues (Cys-SH) into cysteine sulfenic acid (Cys-SOH),…”
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The central role of translation elongation in response to stress by Barros, Géssica C, Guerrero, Sofia, Silva, Gustavo M

“…Protein synthesis is essential to support homeostasis, and thus, must be highly regulated during cellular response to harmful environments. All stages of…”
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Ground‐ and Excited‐State Acidity of Analogs of Red Wine Pyranoanthocyanins by Freitas, Adilson A., Silva, Cassio Pacheco, Silva, Gustavo Thalmer M., Maçanita, António L., Quina, Frank H.

“…Pyranoflavylium cations are synthetic analogs containing the same basic chromophore as the pyranoanthocyanins that form in red wine during maturation and are…”
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Triplet Excited States and Singlet Oxygen Production by Analogs of Red Wine Pyranoanthocyanins by Silva, Gustavo Thalmer M., Thomas, Suma S., Silva, Cassio Pacheco, Schlothauer, Jan C., Baptista, Mauricio S., Freitas, Adilson A., Bohne, Cornelia, Quina, Frank H.

“…During the maturation of red wines, the anthocyanins of grapes are transformed into pyranoanthocyanins, which possess a pyranoflavylium cation as their basic…”
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Redox control of the deubiquitinating enzyme Ubp2 regulates translation during stress by Santos, Clara M., Cizubu, Blanche K., Okonkwo, Dinachi A., Chen, Chia-Yu, Maske, Natori, Snyder, Nathan A., Simões, Vanessa, Washington, Erica J., Silva, Gustavo M.

“…Protein ubiquitination is essential to govern cells’ ability to cope with harmful environments by regulating many aspects of protein dynamics from synthesis to…”
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A computational study of the ground and excited state acidities of synthetic analogs of red wine pyranoanthocyanins by Wang, Jing, Siddique, Farhan, Freitas, Adilson A., Silva, Cassio P., Silva, Gustavo T. M., Quina, Frank H., Lischka, Hans, Aquino, Adelia J. A.

“…The color of mature red wines is due in large part to the chemical transformation of grape anthocyanins into pyranoanthocyanins. Given the difficulties of…”
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