Search Results - "Silva, Catarina"

A prion-like domain in ELF3 functions as a thermosensor in Arabidopsis by Jung, Jae-Hoon, Barbosa, Antonio D., Hutin, Stephanie, Kumita, Janet R., Gao, Mingjun, Derwort, Dorothee, Silva, Catarina S., Lai, Xuelei, Pierre, Elodie, Geng, Feng, Kim, Sol-Bi, Baek, Sujeong, Zubieta, Chloe, Jaeger, Katja E., Wigge, Philip A.

“…Temperature controls plant growth and development, and climate change has already altered the phenology of wild plants and crops 1 . However, the mechanisms by…”
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Tauopathies: Deciphering Disease Mechanisms to Develop Effective Therapies by Silva, M Catarina, Haggarty, Stephen J

“…Tauopathies are neurodegenerative diseases characterized by the pathological accumulation of microtubule-associated protein tau (MAPT) in the form of…”
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Prolonged tau clearance and stress vulnerability rescue by pharmacological activation of autophagy in tauopathy neurons by Silva, M. Catarina, Nandi, Ghata A., Tentarelli, Sharon, Gurrell, Ian K., Jamier, Tanguy, Lucente, Diane, Dickerson, Bradford C., Brown, Dean G., Brandon, Nicholas J., Haggarty, Stephen J.

“…Tauopathies are neurodegenerative diseases associated with accumulation of abnormal tau protein in the brain. Patient iPSC-derived neuronal cell models…”
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Human pluripotent stem cell–derived models and drug screening in CNS precision medicine by Silva, M. Catarina, Haggarty, Stephen J.

“…Development of effective therapeutics for neurological disorders has historically been challenging partly because of lack of accurate model systems in which to…”
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Molecular mechanisms of Evening Complex activity in Arabidopsis by Silva, Catarina S., Nayak, Aditya, Lai, Xuelei, Hutin, Stephanie, Hugouvieux, Véronique, Jung, Jae-Hoon, López-Vidriero, Irene, Franco-Zorrilla, Jose M., Panigrahi, Kishore C. S., Nanao, Max H., Wigge, Philip A., Zubieta, Chloe

“…The Evening Complex (EC), composed of the DNA binding protein LUX ARRHYTHMO (LUX) and two additional proteins EARLY FLOWERING 3 (ELF3) and ELF4, is a…”
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Tetramerization of MADS family transcription factors SEPALLATA3 and AGAMOUS is required for floral meristem determinacy in Arabidopsis by Hugouvieux, Véronique, Silva, Catarina S, Jourdain, Agnès, Stigliani, Arnaud, Charras, Quentin, Conn, Vanessa, Conn, Simon J, Carles, Cristel C, Parcy, François, Zubieta, Chloe

“…Abstract The MADS transcription factors (TF) constitute an ancient family of TF found in all eukaryotes that bind DNA as obligate dimers. Plants have…”
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Red light represses the photophysiology of the scleractinian coral Stylophora pistillata by Wijgerde, Tim, van Melis, Anne, Silva, Catarina I F, Leal, Miguel C, Vogels, Luc, Mutter, Claudia, Osinga, Ronald

“…Light spectrum plays a key role in the biology of symbiotic corals, with blue light resulting in higher coral growth, zooxanthellae density, chlorophyll a…”
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Targeted degradation of aberrant tau in frontotemporal dementia patient-derived neuronal cell models by Silva, M Catarina, Ferguson, Fleur M, Cai, Quan, Donovan, Katherine A, Nandi, Ghata, Patnaik, Debasis, Zhang, Tinghu, Huang, Hai-Tsang, Lucente, Diane E, Dickerson, Bradford C, Mitchison, Timothy J, Fischer, Eric S, Gray, Nathanael S, Haggarty, Stephen J

“…Tauopathies are neurodegenerative diseases characterized by aberrant forms of tau protein accumulation leading to neuronal death in focal brain areas. Positron…”
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Fine-scale population structure and evidence for local adaptation in Australian giant black tiger shrimp (Penaeus monodon) using SNP analysis by Vu, Nga T T, Zenger, Kyall R, Guppy, Jarrod L, Sellars, Melony J, Silva, Catarina N S, Kjeldsen, Shannon R, Jerry, Dean R

“…Restrictions to gene flow, genetic drift, and divergent selection associated with different environments are significant drivers of genetic differentiation…”
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Combining genotypic and phenotypic variation in a geospatial framework to identify sources of mussels in northern New Zealand by Gardner, Jonathan P. A., Silva, Catarina N. S., Norrie, Craig R., Dunphy, Brendon J.

“…The New Zealand green-lipped mussel aquaculture industry is largely dependent on the supply of young mussels that wash up on Ninety Mile Beach (so-called…”
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A new method for quantification of tomatine‐enriched extracts by Faria‐Silva, Catarina, Eleutério, Carla V., Simões, Pedro, Carvalheiro, Manuela, Simões, Sandra

“…BACKGROUND Green tomato extracts, an agro‐food industry waste, are rich in the glycoalkaloid tomatine, which presents activity against several diseases…”
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Mitochondrial and nuclear genetic analyses of the tropical black-lip rock oyster (Saccostrea echinata) reveals population subdivision and informs sustainable aquaculture development by Nowland, Samantha J, Silva, Catarina N S, Southgate, Paul C, Strugnell, Jan M

“…The black-lip rock oyster (Saccostrea echinata) has considerable potential for aquaculture throughout the tropics. Previous attempts to farm S. echinata failed…”
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The intervening domain is required for DNA-binding and functional identity of plant MADS transcription factors by Lai, Xuelei, Vega-Léon, Rosario, Hugouvieux, Veronique, Blanc-Mathieu, Romain, van der Wal, Froukje, Lucas, Jérémy, Silva, Catarina S., Jourdain, Agnès, Muino, Jose M., Nanao, Max H., Immink, Richard, Kaufmann, Kerstin, Parcy, François, Smaczniak, Cezary, Zubieta, Chloe

“…The MADS transcription factors (TF) are an ancient eukaryotic protein family. In plants, the family is divided into two main lineages. Here, we demonstrate…”
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Global drivers of recent diversification in a marine species complex by Silva, Catarina N.S., Murphy, Nicholas P., Bell, James J., Green, Bridget S., Duhamel, Guy, Cockcroft, Andrew C., Hernández, Cristián E., Strugnell, Jan M.

“…Investigating historical gene flow in species complexes can indicate how environmental and reproductive barriers shape genome divergence during speciation. The…”
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Genomic insights of evolutionary divergence and life history innovations in Antarctic brittle stars by Lau, Sally C. Y., Strugnell, Jan M., Sands, Chester J., Silva, Catarina N. S., Wilson, Nerida G.

“…Understanding the drivers of evolutionary innovation provides a crucial perspective of how evolutionary processes unfold across taxa and ecological systems. It…”
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Detecting glacial refugia in the Southern Ocean by Lau, Sally C. Y., Wilson, Nerida G., Silva, Catarina N. S., Strugnell, Jan M.

“…Throughout the Quaternary, the continental‐based Antarctic ice sheets expanded and contracted repeatedly. Evidence suggests that during glacial maxima,…”
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Genomic evidence for West Antarctic Ice Sheet collapse during the Last Interglacial by Lau, Sally C Y, Wilson, Nerida G, Golledge, Nicholas R, Naish, Tim R, Watts, Phillip C, Silva, Catarina N S, Cooke, Ira R, Allcock, A Louise, Mark, Felix C, Linse, Katrin, Strugnell, Jan M

“…The marine-based West Antarctic Ice Sheet (WAIS) is considered vulnerable to irreversible collapse under future climate trajectories, and its tipping point may…”
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Volatile metabolomic signature of human breast cancer cell lines by Silva, Catarina L., Perestrelo, Rosa, Silva, Pedro, Tomás, Helena, Câmara, José S.

“…Breast cancer (BC) remains the most prevalent oncologic pathology in women, causing huge psychological, economic and social impacts on our society. Currently,…”
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Inhibition of p25/Cdk5 Attenuates Tauopathy in Mouse and iPSC Models of Frontotemporal Dementia by Seo, Jinsoo, Kritskiy, Oleg, Watson, L Ashley, Barker, Scarlett J, Dey, Dilip, Raja, Waseem K, Lin, Yuan-Ta, Ko, Tak, Cho, Sukhee, Penney, Jay, Silva, M Catarina, Sheridan, Steven D, Lucente, Diane, Gusella, James F, Dickerson, Bradford C, Haggarty, Stephen J, Tsai, Li-Huei

“…Increased p25, a proteolytic fragment of the regulatory subunit p35, is known to induce aberrant activity of cyclin-dependent kinase 5 (Cdk5), which is…”
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An inhibitor of the proteasomal deubiquitinating enzyme USP14 induces tau elimination in cultured neurons by Boselli, Monica, Lee, Byung-Hoon, Robert, Jessica, Prado, Miguel A., Min, Sang-Won, Cheng, Chialin, Silva, M. Catarina, Seong, Changhyun, Elsasser, Suzanne, Hatle, Ketki M., Gahman, Timothy C., Gygi, Steven P., Haggarty, Stephen J., Gan, Li, King, Randall W., Finley, Daniel

“…The ubiquitin-proteasome system (UPS) is responsible for most selective protein degradation in eukaryotes and regulates numerous cellular processes, including…”
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