Search Results - "Silva, Carlos H. da"

Prescribing errors in a Brazilian teaching hospital: Causes and underlying factors from the perspective of junior doctors by Bonella, Gislaine F, Alves, Letícia da S, Souza, Alicia R N D de, Silva, Carlos H M da

“…In university hospital settings most prescriptions are written by junior doctors, who are more likely to make prescribing errors than experienced doctors…”
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Identification of Novel Chemical Entities for Adenosine Receptor Type 2A Using Molecular Modeling Approaches by Santos, Kelton L B Dos, Cruz, Jorddy N, Silva, Luciane B, Ramos, Ryan S, Neto, Moysés F A, Lobato, Cleison C, Ota, Sirlene S B, Leite, Franco H A, Borges, Rosivaldo S, Silva, Carlos H T P da, Campos, Joaquín M, Santos, Cleydson B R

“…Adenosine Receptor Type 2A (A AR) plays a role in important processes, such as anti-inflammatory ones. In this way, the present work aimed to search for…”
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Pharmacophore and structure-based drug design, molecular dynamics and admet/tox studies to design novel potential pad4 inhibitors by Barcellos, Mariana P., Santos, Cleydson B. R., Federico, Leonardo B., Almeida, Paulo Fernando de, da Silva, Carlos H. T. de Paula, Taft, Carlton A.

“…We have used docking (GLIDE), pharmacophore modeling (Discovery Studio), long trajectory molecular dynamics (Discovery Studio) and ADMET/Tox (QikProp and…”
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Pharmacophore-based virtual screening from phytocannabinoids as antagonist r-CB1 by Correia, Lenir C., Ferreira, Jaderson V., de Lima, Henrique B., Silva, Guilherme M., da Silva, Carlos H. T. P., de Molfetta, Fábio A., Hage-Melim, Lorane I. S.

“…Search for new pharmacological alternatives for obesity is based on the design and development of compounds that can aid in weight loss so that they can be…”
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In silico Screening of Monamine Oxidase B Inhibitors for the Treatment of Central Nervous System Disorders by Costa, Anderson L. P. da, Lima, Henrique B., Silva, Ana C. J., Oliveira, Gabrieli S., Barcelos, Mariana P., Silva, Carlos H. T. P. da, Hage-Melim, Lorane I. S.

“…Worldwide, millions of people suffer from neurological and psychiatric conditions, such as schizophrenia, depression, and neurodegenerative diseases. These…”
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Surface Characterization of Three-Layer Organic Coating Applied on AISI 4130 Steel by Pintaude, Giuseppe, da Silva, Carlos H., Kouketsu, Fernanda, Rovani, Ane C.

“…Resin-bonded molybdenum disulfide (MoS2) is widely applied as a solid lubricant. However, multiple coatings are usually required to meet other requirements in…”
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Expression of Truncated Products at the 5′-Terminal Region of RIPK2 and Evolutive Aspects that Support Their Biological Importance by Villagra, Ulises M M, da Cunha, Bianca R, Polachini, Giovana M, Henrique, Tiago, Stefanini, Ana Carolina Buzzo, de Castro, Tialfi Bergamin, da Silva, Carlos H T P, Feitosa, Olavo A, Fukuyama, Erica E, López, Rossana V M, Dias-Neto, Emmanuel, Nunes, Fabio D, Severino, Patricia, Tajara, Eloiza H

“…Abstract Alternative splicing is the process of generating different mRNAs from the same primary transcript, which contributes to increase the transcriptome…”
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Cannabinoid Type 1 Receptor (CB1) Ligands with Therapeutic Potential for Withdrawal Syndrome in Chemical Dependents of Cannabis sativa by Ferreira, Jaderson V., Chaves, Gisele A., Marino, Bianca L. B., Sousa, Kessia P. A., Souza, Lucilene R., Brito, Maiara F. B., Teixeira, Hueldem R. C., da Silva, Carlos H. T. P., Santos, Cleydson B. R., Hage‐Melim, Lorane I. S.

“…Cannabis sativa withdrawal syndrome is characterized mainly by psychological symptoms. By using computational tools, the aim of this study was to propose drug…”
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Computational design of new protein kinase 2 inhibitors for the treatment of inflammatory diseases using QSAR, pharmacophore-structure-based virtual screening, and molecular dynamics by Cruz, Josiane V., Serafim, Rodolfo B., da Silva, Gabriel M., Giuliatti, Silvana, Rosa, Joaquín M. C., Araújo Neto, Moysés F., Leite, Franco H. A., Taft, Carlton A., da Silva, Carlos H. T. P., Santos, Cleydson B. R.

“…Receptor-interacting protein kinase 2 (RIPK2) plays an essential role in autoimmune response and is suggested as a target for inflammatory diseases. A…”
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Identification of Novel Protein Kinase Receptor Type 2 Inhibitors Using Pharmacophore and Structure-Based Virtual Screening by Cruz, Josiane V, Neto, Moysés F A, Silva, Luciane B, da S Ramos, Ryan, da S Costa, Josivan, Brasil, Davi S B, Lobato, Cleison C, da Costa, Glauber V, Bittencourt, José Adolfo H M, da Silva, Carlos H T P, Leite, Franco H A, Santos, Cleydson B R

“…The Protein Kinase Receptor type 2 (RIPK2) plays an important role in the pathogenesis of inflammatory diseases; it signals downstream of the NOD1 and NOD2…”
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Hierarchical Virtual Screening Based on Rocaglamide Derivatives to Discover New Potential Anti-Skin Cancer Agents by dos Santos, Igor V.F., Borges, Rosivaldo S., Silva, Guilherme M., de Lima, Lúcio R., Bastos, Ruan S., Ramos, Ryan S., Silva, Luciane B., da Silva, Carlos H. T. P., dos Santos, Cleydson B. R.

“…Skin Cancer (SC) is among the most common type of cancers worldwide. The search for SC therapeutics using molecular modeling strategies as well as considering…”
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Short and long-term effects of Baccharis articulata on glucose homeostasis by Kappel, Virginia D, Pereira, Danielle F, Cazarolli, Luisa H, Guesser, Samantha M, da Silva, Carlos H Blum, Schenkel, Eloir P, Reginatto, Flávio H, Silva, Fátima R M B

“…In this study, the in vivo effect of the crude extract and n-butanol and aqueous residual fractions of Baccharis articulata (Lam.) Pers. on serum glucose…”
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Parkinson's Disease: A Review from Pathophysiology to Treatment by Marino, Bianca L B, de Souza, Lucilene R, Sousa, Kessia P A, Ferreira, Jaderson V, Padilha, Elias C, da Silva, Carlos H T P, Taft, Carlton A, Hage-Melim, Lorane I S

“…Parkinson's Disease (PD) is the second most common neurodegenerative disease in the elderly population, with a higher prevalence in men, independent of race…”
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Diketopiperazines produced by endophytic fungi found in association with two Asteraceae species by Guimarães, Denise O., Borges, Warley S., Vieira, Noemi J., de Oliveira, Laiani F., da Silva, Carlos H.T.P., Lopes, Norberto P., Dias, Luis G., Durán-Patrón, Rosa, Collado, Isidro G., Pupo, Mônica T.

“…Three diketopiperazine (DKP) derivatives and four known DKPs were isolated from cultures of three endophytic fungi in the Asteraceae. Diketopiperazine (DKP)…”
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Novel chalcones derivatives with potential antineoplastic activity investigated by docking and molecular dynamics simulations by Neto, Raimundo de A. M., Santos, Cleydson B. R., Henriques, Shayanne V. C., Machado, Letícia de O., Cruz, Jorddy N., da Silva, Carlos H. T. de P., Federico, Leonardo B., Oliveira, Edivaldo H. C. de, de Souza, Michel P. C., da Silva, Patrícia N. B., Taft, Carlton A., Ferreira, Irlon M., Gomes, Madson R. F.

“…Glioblastoma is an aggressive primary tumor of the central nervous system (CNS). Is the most aggressive among infiltrative gliomas arising from the CNS. This…”
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Potential inhibitors of the enzyme acetylcholinesterase and juvenile hormone with insecticidal activity: study of the binding mode via docking and molecular dynamics simulations by Ramos, Ryan S., Macêdo, Williams J. C., Costa, Josivan S., da Silva, Carlos H. T. de P., Rosa, Joaquín M. C., da Cruz, Jorddy Neves, de Oliveira, Mozaniel S., de Aguiar Andrade, Eloisa H., e Silva, Raullyan B. L., Souto, Raimundo N. P., Santos, Cleydson B. R.

“…Models validation in QSAR, pharmacophore, docking and others can ensure the accuracy and reliability of future predictions in design and selection of molecules…”
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Discovery of potential neurodegenerative inhibitors in Alzheimer’s disease by casein kinase 1 structure-based virtual screening by Rodrigues, Ricardo P., Silva, Carlos H. T. P. da

“…Alzheimer’s disease is a progressive neurodegenerative disorder characterized by loss of neurons. Pathological patterns include the presence of amyloid plaques…”
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Current basis for discovery and development of aryl hydrocarbon receptor antagonists for experimental and therapeutic use in atherosclerosis by Pernomian, Larissa, da Silva, Carlos H.T.P.

“…The important role played by aryl hydrocarbon receptor activation in the pathophysiology of atherosclerosis induced by cigarette smoke exposure has spurred the…”
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Effect of initial surface treatment on obtaining a superhydrophobic surface on 5052 aluminum alloy with enhanced anticorrosion properties by da Silva, Rafael G.C., Vieira, Magda R.S., Malta, Maria I.C., da Silva, Carlos H., de Oliveira, Sara H., Filho, Severino L.U.

“…Although there are many studies about superhydrophobicity on aluminum alloys substrates and their resistance to corrosion, few studies have evaluated the…”
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Quality of Life in Obstructive Sleep Apnea Patients Who Underwent Maxillomandibular Advancement Surgery by de Oliveira Squarisi, José M., de Mello Naves, Marcell, Gomes Patrocínio, Lucas, Borges Martins da Silva Paro, Helena, Maria da Silva Mendonça, Tania, Martins da Silva, Carlos H.

“…This study assessed health-related quality of life (HRQOL) and daytime sleepiness in moderate or severe obstructive sleep apnea patients who underwent…”
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