Search Results - "Silva, Bruno F."
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Lipid-Nucleic Acid Complexes: Physicochemical Aspects and Prospects for Cancer Treatment
Published in Molecules (Basel, Switzerland) (28-10-2020)“…Cancer is an extremely complex disease, typically caused by mutations in cancer-critical genes. By delivering therapeutic nucleic acids (NAs) to patients, gene…”
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Cubosome nanoparticles for enhanced delivery of mitochondria anticancer drug elesclomol and therapeutic monitoring via sub-cellular NAD(P)H multi-photon fluorescence lifetime imaging
Published in Nano research (01-05-2019)“…Elesclomol (ELC) is an anticancer drug inducing mitochondria cytotoxicity through reactive oxygen species. Here, for the first time, we encapsulate the poorly…”
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Unravelling a Mechanism of Action for a Cecropin A‑Melittin Hybrid Antimicrobial Peptide: The Induced Formation of Multilamellar Lipid Stacks
Published in Langmuir (06-02-2018)“…An understanding of the mechanism of action of antimicrobial peptides is fundamental to the development of new and more active antibiotics. In the present…”
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4
Smart Artificial Markers for Accurate Visual Mapping and Localization
Published in Sensors (Basel, Switzerland) (18-01-2021)“…Artificial marker mapping is a useful tool for fast camera localization estimation with a certain degree of accuracy in large indoor and outdoor environments…”
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ATRvD1 Attenuates Renal Tubulointerstitial Injury Induced by Albumin Overload in Sepsis-Surviving Mice
Published in International journal of molecular sciences (27-10-2021)“…Novel strategies for the prevention and treatment of sepsis-associated acute kidney injury and its long-term outcomes have been required and remain a challenge…”
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Sustained Release of a Streptococcus pneumoniae Endolysin from Liposomes for Potential Otitis Media Treatment
Published in ACS infectious diseases (13-08-2021)“…Local delivery of antimicrobials for otitis media treatment would maximize therapeutic efficacy while minimizing side effects. However, drug transport across…”
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Unusual Vesicle−Micelle Transitions in a Salt-Free Catanionic Surfactant: Temperature and Concentration Effects
Published in Langmuir (07-10-2008)“…The spontaneous formation of vesicles by the salt-free surfactant hexadecyltrimethylammonium octylsulfonate (TASo) and the features of an unusual…”
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Nematic Director Reorientation at Solid and Liquid Interfaces under Flow: SAXS Studies in a Microfluidic Device
Published in Langmuir (14-04-2015)“…In this work we investigate the interplay between flow and boundary condition effects on the orientation field of a thermotropic nematic liquid crystal under…”
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Cladonia verticillaris (lichen) indicates negative impacts derived from the combustion of biodiesel blends: an alert for the environmental management for biofuels use
Published in Environmental monitoring and assessment (01-12-2021)“…The use of biodiesel blends with petroleum diesel in vehicular engines demands the evaluation of the possible impacts and effects of the gases emitted from…”
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Headgroup Effects on the Unusual Lamellar−Lamellar Coexistence and Vesicle-to-Micelle Transition of Salt-Free Catanionic Amphiphiles
Published in Langmuir (02-03-2010)“…Salt-free ion-paired catanionic amphiphiles of the C m +C n − type, with a high solubility mismatch (n ≫ m or m ≫ n) display a remarkable phase behavior in…”
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Structural transitions induced by shear flow and temperature variation in a nonionic surfactant/water system
Published in Journal of colloid and interface science (15-04-2012)“…[Display omitted] ► Dynamic phase diagram of the 40wt.% C16E4/D2O system. ► Rheo-SANS, rheo-SALS, and rheology elucidate the shear-induced transitions. ►…”
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12
Structural Evolution of Environmentally Responsive Cationic Liposome–DNA Complexes with a Reducible Lipid Linker
Published in Langmuir (17-07-2012)“…Environmentally responsive materials (i.e., materials that respond to changes in their environment with a change in their properties or structure) are…”
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13
In Vitro Evaluation of Lipopolyplexes for Gene Transfection: Comparing 2D, 3D and Microdroplet-Enabled Cell Culture
Published in Molecules (Basel, Switzerland) (18-07-2020)“…Complexes combining nucleic acids with lipids and polymers (lipopolyplexes) show great promise for gene therapy since they enable compositional, physical and…”
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14
In Vitro CRISPR/Cas9 Transfection and Gene-Editing Mediated by Multivalent Cationic Liposome-DNA Complexes
Published in Pharmaceutics (19-05-2022)“…Clustered regularly interspaced short palindromic repeats (CRISPR) and CRISPR-associated nuclease 9 (Cas9) gene-editing offers exciting new therapeutic…”
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15
A Versatile Nanocarrier-Cubosomes, Characterization, and Applications
Published in Nanomaterials (Basel, Switzerland) (29-06-2022)“…The impact of nanotechnology on the exponential growth of several research areas, particularly nanomedicine, is undeniable. The ability to deliver active…”
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Chain length mismatch and packing effects on the thermotropic phase behavior of salt-free catanionic surfactants
Published in Journal of colloid and interface science (01-09-2013)“…[Display omitted] •Chain length mismatch in catanionic surfactants induces rich mesomorphism.•Unexpected trends in phase transition temperatures and enthalpies…”
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A Versatile Method for Depth Data Error Estimation in RGB-D Sensors
Published in Sensors (Basel, Switzerland) (16-09-2018)“…We propose a versatile method for estimating the RMS error of depth data provided by generic 3D sensors with the capability of generating RGB and depth ( )…”
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18
Rapidly dissolving microneedles for the delivery of cubosome-like liquid crystalline nanoparticles with sustained release of rapamycin
Published in International journal of pharmaceutics (15-12-2020)“…[Display omitted] In this study, we developed a system for the transdermal delivery and controlled release of the hydrophobic immunosuppressive drug rapamycin,…”
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Size, Shape, and Charge of Salt-Free Catanionic Microemulsion Droplets: A Small-Angle Neutron Scattering and Modeling Study
Published in The journal of physical chemistry. B (30-07-2009)“…The formation and microstructure of a novel microemulsion based on a salt-free catanionic surfactant have been examined by considering the…”
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Lamellar Miscibility Gap in a Binary Catanionic Surfactant−Water System
Published in The journal of physical chemistry. B (06-12-2007)“…The coexistence of two lamellar liquid-crystalline phases in equilibrium for binary surfactant−water systems is a rare and still puzzling phenomenon. In the…”
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