Search Results - "Silva, Artur M. S."

Special Issue "Recent Advances in the Synthesis, Functionalization and Applications of Pyrazole-Type Compounds II" by Silva, Vera L M, Silva, Artur M S

“…Pyrazole and its derivatives are considered privileged -heterocycles with immense therapeutic potential [...]…”
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Macroalgae Specialized Metabolites: Evidence for Their Anti-Inflammatory Health Benefits by Rocha, Djenisa H A, Pinto, Diana C G A, Silva, Artur M S

“…Inflammation is an organism's response to chemical or physical injury. It is split into acute and chronic inflammation and is the last, most significant cause…”
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Chromones: A Promising Ring System for New Anti-inflammatory Drugs by Silva, Carlos F. M., Pinto, Diana C. G. A., Silva, Artur M. S.

“…The quest for safer anti‐inflammatory drugs is still the focus of several medicinal chemistry programs. Chromones (4H‐chromen‐4‐ones) are a group of naturally…”
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Overview of phlorotannins’ constituents in Fucales by Catarino, Marcelo D., Pires, Sónia M. G., Silva, Sónia, Costa, Filipa, Braga, Susana S., Pinto, Diana C. G. A., Silva, Artur M. S., Cardoso, Susana M.

“…Fucales are an order within the Phaeophyceae that include most of the common littoral seaweeds in temperate and subtropical coastal regions. Many species of…”
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Monoterpene Hydroxy Lactones Isolated from Thalassiosira sp. Microalga and Their Antibacterial and Antioxidant Activities by Morais, Alcina M. M. B., Kumla, Decha, Martins, Valter F. R., Alves, Ana, Gales, Luis, Silva, Artur M. S., Costa, Paulo M., Mistry, Sharad, Kijjoa, Anake, Morais, Rui M. S. C.

“…Two monoterpenoid lactones, loliolide (1) and epi-loliolide (2), were isolated from the crude dichloromethane extract of a microalga, Thalassiosira sp.). The…”
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Flavonoids as Therapeutic Compounds Targeting Key Proteins Involved in Alzheimer’s Disease by Baptista, Filipa I, Henriques, Ana G, Silva, Artur M. S, Wiltfang, Jens, da Cruz e Silva, Odete A. B

“…Alzheimer’s disease is characterized by pathological aggregation of protein tau and amyloid-β peptides, both of which are considered to be toxic to neurons…”
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Plant Flavonoids: Chemical Characteristics and Biological Activity by Dias, Maria Celeste, Pinto, Diana C. G. A., Silva, Artur M. S.

“…In recent years, more attention has been paid to natural sources of antioxidants. Flavonoids are natural substances synthesized in several parts of plants that…”
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Chromatographic and spectroscopic analysis of heavy crude oil mixtures with emphasis in nuclear magnetic resonance spectroscopy: A review by Silva, Sandra L., Silva, Artur M.S., Ribeiro, Jorge C., Martins, Fernando G., Da Silva, Francisco A., Silva, Carlos M.

“…The chromatographic and spectroscopic techniques used to characterize heavy crude oils, although more focused in the nuclear magnetic resonance spectroscopy as…”
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Microbe-Assisted Phytoremediation of Hydrocarbons in Estuarine Environments by Oliveira, Vanessa, Gomes, Newton C. M, Almeida, Adelaide, Silva, Artur M. S, Silva, Helena, Cunha, Ângela

“…Estuaries are sinks for various anthropogenic contaminants, such as petroleum hydrocarbons, giving rise to significant environmental concern. The demand for…”
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Flavonoids Inhibit COX-1 and COX-2 Enzymes and Cytokine/Chemokine Production in Human Whole Blood by Ribeiro, Daniela, Freitas, Marisa, Tomé, Sara M., Silva, Artur M. S., Laufer, Stefan, Lima, José L. F. C., Fernandes, Eduarda

“…Cyclooxygenase 2 (COX-2) and the production of cytokines/chemokines are important targets for the modulation of the inflammatory response. Although a large…”
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2-Styrylchromones Prevent IL-1β-Induced Pro-Inflammatory Activation of Fibroblast-like Synoviocytes while Increasing COX-2 Expression by Rufino, Ana Teresa, Lucas, Mariana, Silva, Artur M S, Ribeiro, Daniela, Fernandes, Eduarda

“…Rheumatoid arthritis (RA) is characterized by systemic immune and chronic inflammatory features, leading to the destruction of the joints. Presently, there are…”
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Evolution of the Quinoline Scaffold for the Treatment of Leishmaniasis: A Structural Perspective by Silva, Carlos F M, Pinto, Diana C G A, Fernandes, Pedro A, Silva, Artur M S

“…Since the beginning of the XXI century, Leishmaniasis has been integrated into the World Health Organization's list of the 20 neglected tropical diseases,…”
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Ion Specific Effects on the Mutual Solubilities of Water and Hydrophobic Ionic Liquids by Freire, Mara G, Carvalho, Pedro J, Silva, Artur M. S, Santos, Luís M. N. B. F, Rebelo, Luís P. N, Marrucho, Isabel M, Coutinho, João A. P

“…Ion specific effects on the mutual solubilities between hydrophobic ionic liquids (ILs) and water are complex and not fully understood. The aim of this work is…”
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Lipophilic profile of the edible halophyte Salicornia ramosissima by ISCA, Vera M. S, SECA, Ana M. L, PINTO, Diana C. G. A, SILVA, Helena, SILVA, Artur M. S

“…Salicornia ramosissima J. Woods is considered, in the Iberian Peninsula and France, a gourmet product. Nevertheless, is one of the less studied Salicornia…”
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Metabolomics as a Tool to Understand Nano-Plant Interactions: The Case Study of Metal-Based Nanoparticles by Silva, Sónia, Dias, Maria Celeste, Pinto, Diana C G A, Silva, Artur M S

“…Metabolomics is a powerful tool in diverse research areas, enabling an understanding of the response of organisms, such as plants, to external factors, their…”
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The dipeptidyl peptidase-4 inhibitory effect of flavonoids is hindered in protein rich environments by Proença, Carina, Freitas, Marisa, Ribeiro, Daniela, Tomé, Sara M, Araújo, Alberto N, Silva, Artur M S, Fernandes, Pedro A, Fernandes, Eduarda

“…Dipeptidyl peptidase-4 (DPP-4) inhibitors present a unique approach for the management of type 2 diabetes (T2D). In the present study, the inhibition of DPP-4…”
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Ohmic Heating-Assisted Synthesis of 3‑Arylquinolin-4(1H)‑ones by a Reusable and Ligand-Free Suzuki–Miyaura Reaction in Water by Pinto, Joana, Silva, Vera L. M, Silva, Ana M. G, Santos, Luís M. N. B. F, Silva, Artur M. S

“…Potential bioactive 3-arylquinolin-4­(1H)-ones were synthesized under ohmic heating using an efficient, reusable, and ligand-free protocol developed for the…”
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Studying and Analyzing Humane Endpoints in the Fructose-Fed and Streptozotocin-Injected Rat Model of Diabetes by Silva-Reis, Rita, Faustino-Rocha, Ana I, Silva, Jéssica, Valada, Abigaël, Azevedo, Tiago, Anjos, Lara, Gonçalves, Lio, Pinto, Maria de Lurdes, Ferreira, Rita, Silva, Artur M S, Cardoso, Susana M, Oliveira, Paula A

“…This work aimed to define a humane endpoint scoring system able to objectively identify signs of animal suffering in a rat model of type 2 diabetes…”
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Ultrasound-Assisted Wittig Reaction for the Synthesis of 3-Substituted 4-Chloroquinolines and Quinolin-4(1H)-ones with Extended π-Conjugated Systems by Frites, Wahiba, Khalfaoui, Massaab, Hammal, Lamouri, Silva, Vera L. M., Silva, Artur M. S.

“…3-(Vinyl-/buta-1,3-dien-1-yl/4-phenylbuta-1,3-dien-1-yl)-4-chloro quinolines and quinolin-4(1H)-ones were synthesized by ultrasound-assisted Wittig reaction of…”
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Gossypetin Is a Novel Modulator of Inflammatory Cytokine Production and a Suppressor of Osteosarcoma Cell Growth by Proença, Carina, Rufino, Ana Teresa, Santos, Isabela, Albuquerque, Hélio M. T, Silva, Artur M. S, Fernandes, Eduarda, Ferreira de Oliveira, José Miguel P

“…Osteosarcoma (OS) is a common childhood sarcoma, and its treatment is hindered by adverse effects, chemoresistance, and recurrence. Interleukin (IL)-6…”
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