Strategies for Preventing and Treating Oral Mucosal Infections Associated with Removable Dentures: A Scoping Review

Oral infections occur due to contact between biofilm rich in formed on the inner surface of complete dentures and the mucosa. This study investigated historical advances in the prevention and treatment of oral mucosal infection and identified gaps in the literature. Bibliographic research was conduc...

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Bibliographic Details
Published in:	Antibiotics (Basel) Vol. 13; no. 3; p. 273
Main Authors:	Ribeiro, Adriana Barbosa, Pizziolo, Pillar Gonçalves, Clemente, Lorena Mosconi, Aguiar, Helena Cristina, Poker, Beatriz de Camargo, Silva, Arthur Augusto Martins E, Makrakis, Laís Ranieri, Fifolato, Marco Aurelio, Souza, Giulia Cristina, Oliveira, Viviane de Cássia, Watanabe, Evandro, Lovato da Silva, Cláudia Helena
Format:	Journal Article
Language:	English
Published:	Switzerland MDPI AG 01-03-2024 MDPI
Subjects:	antifungal agents Antimicrobial agents Biofilms Candida albicans Care and treatment Chemical control Classification Dental materials denture Dentures Disinfectants Erythema Hygiene Implants, Artificial In vivo methods and tests Infection infection control Infections Inflammation Literature reviews Microorganisms Mucosa Natural products Oral hygiene Patients Prevention Prostheses Prosthesis Review Sodium hypochlorite stomatitis Taste disorders Type 2 diabetes Candida albicans oral hygiene antifungal agents stomatitis denture cleansers review infection control complete denture biofilms acrylic resins
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Summary:	Oral infections occur due to contact between biofilm rich in formed on the inner surface of complete dentures and the mucosa. This study investigated historical advances in the prevention and treatment of oral mucosal infection and identified gaps in the literature. Bibliographic research was conducted, looking at PubMed, Embase, Web of Science, and Scopus, where 935 articles were found. After removing duplicates and excluding articles by reading the title and abstract, 131 articles were selected for full reading and 104 articles were included. Another 38 articles were added from the gray literature. This review followed the PRISMA-ScR guidelines. The historical period described ranges from 1969 to 2023, in which, during the 21st century, in vitro and in vivo studies became more common and, from 2010 to 2023, the number of randomized controlled trials increased. Among the various approaches tested are the incorporation of antimicrobial products into prosthetic materials, the improvement of oral and denture hygiene protocols, the development of synthetic and natural products for the chemical control of microorganisms, and intervention with local or systemic antimicrobial agents. Studies report good results with brushing combined with sodium hypochlorite, and new disinfectant solutions and products incorporated into prosthetic materials are promising.
Bibliography:	ObjectType-Article-2 SourceType-Scholarly Journals-1 ObjectType-Feature-3 content type line 23 ObjectType-Review-1
ISSN:	2079-6382 2079-6382
DOI:	10.3390/antibiotics13030273