Search Results - "Silva, Andrea G"

Synthesis, Structural and Thermal Studies of 3-(1-Benzyl-1,2,3,6-tetrahydropyridin-4-yl)-5-ethoxy-1H-indole (D2AAK1_3) as Dopamine D2 Receptor Ligand by Kondej, Magda, Bartyzel, Agata, Pitucha, Monika, Wróbel, Tomasz, Silva, Andrea, Matosiuk, Dariusz, Castro, Marián, Kaczor, Agnieszka

“…Compound D2AAK1_3 was designed as a modification of the lead structure D2AAK1 (an in vivo active multi-target compound with nanomolar affinity to a number of…”
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Exercise Training Does Improve Cardiorespiratory Fitness in Post-Bariatric Surgery Patients by da Silva, Andréa L. G., Sardeli, Amanda V., André, Larissa D., Severin, Richard, de Oliveira, Claudio R., Hassan, Chandra, Borghi-Silva, Audrey, Phillips, Shane A.

“…Although exercise is recognized as an important component of the management for patients following bariatric surgery (BS), its effectiveness on…”
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N -(2-Hydroxyphenyl)-1-[3-(2-oxo-2,3-dihydro-1 H - benzimidazol-1-yl)propyl]piperidine-4-Carboxamide (D2AAK4), a Multi-Target Ligand of Aminergic GPCRs, as a Potential Antipsychotic by Kaczor, Agnieszka A, Targowska-Duda, Katarzyna M, Silva, Andrea G, Kondej, Magda, Biała, Grażyna, Castro, Marián

“…-(2-hydroxyphenyl)-1-[3-(2-oxo-2,3-dihydro-1 -benzimidazol -1-yl)propyl]piperidine-4-carboxamide (D2AAK4) is a multitarget ligand of aminergic G…”
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1-(2'-Bromobenzyl)-6,7-dihydroxy- N -methyl-tetrahydroisoquinoline and 1,2-Demethyl-nuciferine as Agonists in Human D 2 Dopamine Receptors by Silva, Andrea G, Vila, Laura, Marques, Patrice, Moreno, Laura, Loza, Mabel, Sanz, María-Jesús, Cortes, Diego, Castro, Marián, Cabedo, Nuria

“…Certain D -like dopamine receptor (DR) agonists are useful therapeutically as antiparkinsonian drugs, whereas D -like DR antagonists or partial agonists are…”
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Structure-Based Virtual Screening for Dopamine D2 Receptor Ligands as Potential Antipsychotics by Kaczor, Agnieszka A., Silva, Andrea G., Loza, María I., Kolb, Peter, Castro, Marián, Poso, Antti

“…Structure‐based virtual screening using a D2 receptor homology model was performed to identify dopamine D2 receptor ligands as potential antipsychotics. From…”
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N-(3-{4-[3-(trifluoromethyl)phenyl]piperazin-1-yl}propyl)-1H-indazole-3-carboxamide (D2AAK3) as a potential antipsychotic: In vitro, in silico and in vivo evaluation of a multi-target ligand by Kaczor, Agnieszka A., Targowska-Duda, Katarzyna M., Stępnicki, Piotr, Silva, Andrea G., Koszła, Oliwia, Kędzierska, Ewa, Grudzińska, Angelika, Kruk-Słomka, Marta, Biała, Grażyna, Castro, Marián

“…Schizophrenia is a mental illness of not adequately understood causes that is not satisfactorily enough treated by current antipsychotics. In search for novel…”
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Synthesis, pharmacological and structural studies of 5-substituted-3-(1-arylmethyl-1,2,3,6-tetrahydropyridin-4-yl)-1H-indoles as multi-target ligands of aminergic GPCRs by Kondej, Magda, Wróbel, Tomasz M., Silva, Andrea G., Stępnicki, Piotr, Koszła, Oliwia, Kędzierska, Ewa, Bartyzel, Agata, Biała, Grażyna, Matosiuk, Dariusz, Loza, Maria I., Castro, Marián, Kaczor, Agnieszka A.

“…Schizophrenia is a complex disease with not fully understood pathomechanism, involving many neurotransmitters and their receptors. This is why it is best…”
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1‑(2′-Bromobenzyl)-6,7-dihydroxy‑N‑methyl-tetrahydroisoquinoline and 1,2-Demethyl-nuciferine as Agonists in Human D2 Dopamine Receptors by Silva, Andrea G, Vila, Laura, Marques, Patrice, Moreno, Laura, Loza, Mabel, Sanz, María-Jesús, Cortes, Diego, Castro, Marián, Cabedo, Nuria

“…Certain D2-like dopamine receptor (DR) agonists are useful therapeutically as antiparkinsonian drugs, whereas D2-like DR antagonists or partial agonists are…”
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In vitro, molecular modeling and behavioral studies of 3-{[4-(5-methoxy-1H-indol-3-yl)-1,2,3,6-tetrahydropyridin-1-yl]methyl}-1,2-dihydroquinolin-2-one (D2AAK1) as a potential antipsychotic by Kaczor, Agnieszka A., Targowska-Duda, Katarzyna M., Budzyńska, Barbara, Biała, Grażyna, Silva, Andrea G., Castro, Marián

“…Antipsychotics currently available to treat schizophrenia suffer several limitations: (1) they are efficient against positive but not negative and cognitive…”
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Corrigendum to “In vitro, molecular modeling and behavioral studies of '3-{[4-(5-methoxy-1H-indol-3-yl)-1,2,3,6-tetrahydropyridin-1-yl]methyl}-1,2-dihydroquinolin-2-one (D2AAK1) as a potential antipsychotic” [Neurochem. Int. 96 (2016) 84–99] by Kaczor, Agnieszka A., Targowska-Duda, Katarzyna M., Budzyńska, Barbara, Biała, Grażyna, Silva, Andrea G., Castro, Marián

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Thoracoabdominal mobility evaluation of asthmatic patients in physiotherapy practice: Intra‐rater reliability by Caruso, Flávia R., Trimer, Renata, da Luz Goulart, Cassia, Ricci, Paula A., Araújo, Adriana S.G., Carmargo, Patrícia, Marinho, Renan S., Baptista, Polliana, Silva, Andrea L.G., Mendes, Renata G., Borghi‐Silva, Audrey

“…Background The evaluation of thoracoabdominal mobility is a tool extensively used in the physiotherapy practice in different populations. Photogrammetry may be…”
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Deoxyribonucleic acid damage and repair response in the chemotherapy of lung cancer: cross-sectional study by SCHNEIDER, MARCIA R., SILVA, ANDRÉA L.G. DA, GOULART, CÁSSIA L., SCHNEIDERS, PALOMA B., WEBER, AUGUSTO F., POSSUELO, LIA G., VALIM, ANDREIA R.M.

“…This study evaluated 24 patients with lung cancer (CA) and 23 individuals with no smoking history or cancer in the family and without respiratory disease in…”
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Structure‐Based Virtual Screening for Dopamine D 2 Receptor Ligands as Potential Antipsychotics by Kaczor, Agnieszka A., Silva, Andrea G., Loza, María I., Kolb, Peter, Castro, Marián, Poso, Antti

“…Abstract Structure‐based virtual screening using a D 2 receptor homology model was performed to identify dopamine D 2 receptor ligands as potential…”
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Allosteric modulation of dopamine D 2L receptor in complex with G i1 and G i2 proteins: the effect of subtle structural and stereochemical ligand modifications by Żuk, Justyna, Bartuzi, Damian, Silva, Andrea G, Pitucha, Monika, Koszła, Oliwia, Wróbel, Tomasz M, Matosiuk, Dariusz, Castro, Marián, Kaczor, Agnieszka A

“…Allosteric modulation of G protein-coupled receptors (GPCRs) is nowadays one of the hot topics in drug discovery. In particular, allosteric modulators of D…”
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Structure-Based Virtual Screening for Dopamine D sub(2) Receptor Ligands as Potential Antipsychotics by Kaczor, Agnieszka A, Silva, Andrea G, Loza, Maria I, Kolb, Peter, Castro, Marian, Poso, Antti

“…Structure-based virtual screening using a D sub(2) receptor homology model was performed to identify dopamine D sub(2) receptor ligands as potential…”
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Synthesis, Structural and Thermal Studies of 3-(1-Benzyl-1,2,3,6-tetrahydropyridin-4-yl)-5-ethoxy-1 H -indole (D2AAK1_3) as Dopamine D₂ Receptor Ligand by Kondej, Magda, Bartyzel, Agata, Pitucha, Monika, Wróbel, Tomasz M, Silva, Andrea G, Matosiuk, Dariusz, Castro, Marián, Kaczor, Agnieszka A

“…Compound D2AAK1_3 was designed as a modification of the lead structure D2AAK1 (an in vivo active multi-target compound with nanomolar affinity to a number of…”
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DNA Damage and Oxidative Stress in Patients with Chronic Obstructive Pulmonary Disease by Silva, Andréa Lúcia G da, Rosa, Helen T da, Charlier, Clara F, Salvador, Miriam, Moura, Dinara J, Moura Valim, Andreia R de, Guecheva, Temenouga N, Henriques, João Antônio Pegas

“…Background: We aimed to assess the level of DNA damage and susceptibility to exogenous mutagens in peripheral blood cells of Chronic Obstructive Pulmonary…”
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Acute effects of expiratory positive pressure on autonomic cardiac modulation during spontaneous and slow deep breathing in COPD patients by SILVA, ANDRÉA L.G. DA, GOULART, CÁSSIA L., MANSOUR, KAMILA M.K., BACK, GUILHERME D., CABIDDU, RAMONA, TRIMER, RENATA, BORGHI-SILVA, AUDREY

“…AIMto evaluate the acute effects of expiratory positive airway pressure on cardiac autonomic modulation in chronic obstructive pulmonary disease patients…”
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CAT correlates positively with respiratory rate and is a significant predictor of the impact of COPD on daily life of patients: a cross sectional study by Becker, Cíntia, Schäfer, Janaína, Carvalho, Lisiane L., Vitiello, Isabel P., Da Silva, Andréa L.G.

“…Background: The pathophysiological changes of COPD tend to worsen with progression, triggering limiting symptoms and implying the decrease in the activities of…”
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