Search Results - "Silva, Amélia M."
-
1
Polymeric nanoparticles: production, characterization, toxicology and ecotoxicology
Published in Molecules (Basel, Switzerland) (15-08-2020)“…Polymeric nanoparticles (NPs) are particles within the size range from 1 to 1000 nm and can be loaded with active compounds entrapped within or…”
Get full text
Journal Article -
2
Metal-based nanoparticles as antimicrobial agents: an overview
Published in Nanomaterials (Basel, Switzerland) (09-02-2020)“…Metal-based nanoparticles have been extensively investigated for a set of biomedical applications. According to the World Health Organization, in addition to…”
Get full text
Journal Article -
3
Nanoparticle Delivery Systems in the Treatment of Diabetes Complications
Published in Molecules (Basel, Switzerland) (20-11-2019)“…Diabetes mellitus, an incurable metabolic disease, is characterized by changes in the homeostasis of blood sugar levels, being the subcutaneous injection of…”
Get full text
Journal Article -
4
Memantine loaded PLGA PEGylated nanoparticles for Alzheimer's disease: in vitro and in vivo characterization
Published in Journal of nanobiotechnology (27-03-2018)“…Memantine, drug approved for moderate to severe Alzheimer's disease, has not shown to be fully effective. In order to solve this issue, polylactic-co-glycolic…”
Get full text
Journal Article -
5
(+)-Limonene 1,2-Epoxide-Loaded SLNs: Evaluation of Drug Release, Antioxidant Activity, and Cytotoxicity in an HaCaT Cell Line
Published in International journal of molecular sciences (20-02-2020)“…In this work, we developed a solid lipid nanoparticle (SLN) formulation with (+)-limonene 1,2-epoxide and glycerol monostearate (Lim-SLNs), stabilized with…”
Get full text
Journal Article -
6
Development and Optimization of Alpha-Pinene-Loaded Solid Lipid Nanoparticles (SLN) Using Experimental Factorial Design and Dispersion Analysis
Published in Molecules (Basel, Switzerland) (24-07-2019)“…The encapsulation of bicyclic monoterpene α-pinene into solid lipid nanoparticles (SLN) is reported using experimental factorial design, followed by high-end…”
Get full text
Journal Article -
7
Parental metabolic syndrome epigenetically reprograms offspring hepatic lipid metabolism in mice
Published in The Journal of clinical investigation (01-05-2020)“…The prevalence of nonalcoholic fatty liver disease (NAFLD) is increasing worldwide. Although gene-environment interactions have been implicated in the etiology…”
Get full text
Journal Article -
8
Physicochemical and biopharmaceutical aspects influencing skin permeation and role of SLN and NLC for skin drug delivery
Published in Heliyon (01-02-2022)“…The skin is a complex and multifunctional organ, in which the static versus dynamic balance is responsible for its constant adaptation to variations in the…”
Get full text
Journal Article -
9
Hawthorn (Crataegus spp.): An Updated Overview on Its Beneficial Properties
Published in Forests (01-05-2020)“…Medicinal plants, many of which are wild, have recently been under the spotlight worldwide due to growing requests for natural and sustainable eco-compatible…”
Get full text
Journal Article -
10
Biopharmaceutical evaluation of epigallocatechin gallate-loaded cationic lipid nanoparticles (EGCG-LNs): In vivo, in vitro and ex vivo studies
Published in International journal of pharmaceutics (11-04-2016)“…Transcorneal permeation profile of EGCG-CTAB LNs (■) and EGCG-DDAB LNs (♦), and respective stereomicrographs of the CAM after 5min of exposure to lipid…”
Get full text
Journal Article -
11
Therapeutic Approaches for Age-Related Macular Degeneration
Published in International journal of molecular sciences (04-10-2022)“…Damage to the retinal pigment epithelium, Bruch's membrane and/or tissues underlying macula is known to increase the risk of age-related macular degeneration…”
Get full text
Journal Article -
12
Surface engineering of silica nanoparticles for oral insulin delivery: characterization and cell toxicity studies
Published in Colloids and surfaces, B, Biointerfaces (01-11-2014)“…The present work aimed at studying the interaction between insulin and SiNP surfaced with mucoadhesive polymers (chitosan, sodium alginate or polyethylene…”
Get full text
Journal Article -
13
Interaction of Hydrophobic Ionic Liquids with Lipids in Langmuir Monolayers
Published in Langmuir (03-04-2018)“…The interaction of two ionic liquids, trihexyl(tetradecyl)phosphonium bis(trifluoromethylsulfonyl)-imide and trihexyl(tetradecyl)phosphonium dicyanamide,…”
Get full text
Journal Article -
14
Nanoencapsulation of polyphenols for protective effect against colon–rectal cancer
Published in Biotechnology advances (01-09-2013)“…The human population at large is exposed to many critical factors (e.g. bad food habits, chemical substances, and stress) leading to the development of serious…”
Get full text
Journal Article -
15
In Vitro Cytotoxicity of Oleanolic/Ursolic Acids-Loaded in PLGA Nanoparticles in Different Cell Lines
Published in Pharmaceutics (24-07-2019)“…Oleanolic (OA) and ursolic (UA) acids are recognized triterpenoids with anti-cancer properties, showing cell-specific activity that can be enhanced when loaded…”
Get full text
Journal Article -
16
Cationic solid lipid nanoparticles interfere with the activity of antioxidant enzymes in hepatocellular carcinoma cells
Published in International journal of pharmaceutics (25-08-2014)“…[Display omitted] Solid lipid nanoparticles (SLN) are colloidal drug and/or gene carriers developed from solid lipids and surfactants that are considered safe…”
Get full text
Journal Article -
17
Soft Cationic Nanoparticles for Drug Delivery: Production and Cytotoxicity of Solid Lipid Nanoparticles (SLNs)
Published in Applied sciences (01-10-2019)“…The surface properties of nanoparticles have decisive influence on their interaction with biological barriers (i.e., living cells), being the concentration and…”
Get full text
Journal Article -
18
Two- and Three-Dimensional Spectrofluorimetric Qualitative Analysis of Selected Vegetable Oils for Biomedical Applications
Published in Molecules (Basel, Switzerland) (28-11-2020)“…Vegetable oils obtained from different plants are known for their beneficial effects on prophylaxis and supportive treatment of a great deal of…”
Get full text
Journal Article -
19
Perillaldehyde 1,2-epoxide loaded SLN-tailored mAb: production, physicochemical characterization and in vitro cytotoxicity profile in MCF-7 cell lines
Published in Pharmaceutics (16-02-2020)“…We have developed a new cationic solid lipid nanoparticle (SLN) formulation, composed of Compritol ATO 888, poloxamer 188 and cetyltrimethylammonium bromide…”
Get full text
Journal Article -
20
Quinoline- and benzoselenazole-derived unsymmetrical squaraine cyanine dyes: design, synthesis, photophysicochemical features and light-triggerable antiproliferative effects against breast cancer cell lines
Published in Materials (10-06-2020)“…Photodynamic therapy is an innovative treatment approach broadly directed towards oncological diseases. Its applicability and efficiency are closely related to…”
Get full text
Journal Article