Search Results - "Silonov, Sergey A."

Liquid–liquid phase separation as an organizing principle of intracellular space: overview of the evolution of the cell compartmentalization concept by Antifeeva, Iuliia A., Fonin, Alexander V., Fefilova, Anna S., Stepanenko, Olesya V., Povarova, Olga I., Silonov, Sergey A., Kuznetsova, Irina M., Uversky, Vladimir N., Turoverov, Konstantin K.

“…At the turn of the twenty-first century, fundamental changes took place in the understanding of the structure and function of proteins and then in the…”
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PML Body Biogenesis: A Delicate Balance of Interactions by Silonov, Sergey A, Smirnov, Eugene Y, Kuznetsova, Irina M, Turoverov, Konstantin K, Fonin, Alexander V

“…PML bodies are subnuclear protein complexes that play a crucial role in various physiological and pathological cellular processes. One of the general…”
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Insights into the Cellular Localization and Functional Properties of TSPYL5 Protein by Silonov, Sergey A, Smirnov, Eugene Y, Shmidt, Eva A, Kuznetsova, Irina M, Turoverov, Konstantin K, Fonin, Alexander V

“…In recent years, the role of liquid-liquid phase separation (LLPS) and intrinsically disordered proteins (IDPs) in cellular molecular processes has received…”
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The Role of Non-Specific Interactions in Canonical and ALT-Associated PML-Bodies Formation and Dynamics by Fonin, Alexander V., Silonov, Sergey A., Shpironok, Olesya G., Antifeeva, Iuliia A., Petukhov, Alexey V., Romanovich, Anna E., Kuznetsova, Irina M., Uversky, Vladimir N., Turoverov, Konstantin K.

“…In this work, we put forward a hypothesis about the decisive role of multivalent nonspecific interactions in the early stages of PML body formation. Our…”
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Naphthyl-Substituted Indole and Pyrrole Carboxylic Acids as Effective Antibiotic Potentiators—Inhibitors of Bacterial Cystathionine γ-Lyase by Kuzovlev, Andrey S, Zybalov, Mikhail D, Golovin, Andrey V, Gureev, Maxim A, Kasatkina, Mariia A, Biryukov, Mikhail V, Belik, Albina R, Silonov, Sergey A, Yunin, Maxim A, Zigangirova, Nailya A, Reshetnikov, Vasiliy V, Isakova, Yulia E, Porozov, Yuri B, Ivanov, Roman A

“…Over the past decades, the problem of bacterial resistance to most antibiotics has become a serious threat to patients’ survival. Nevertheless, antibiotics of…”
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New Evidence of the Importance of Weak Interactions in the Formation of PML-Bodies by Fonin, Alexander V, Silonov, Sergey A, Fefilova, Anna S, Stepanenko, Olesya V, Gavrilova, Anastasia A, Petukhov, Alexey V, Romanovich, Anna E, Modina, Anna L, Zueva, Tatiana S, Nedelyaev, Evgeniy M, Pleskach, Nadejda M, Kuranova, Mirya L, Kuznetsova, Irina M, Uversky, Vladimir N, Turoverov, Konstantin K

“…In this work, we performed a comparative study of the formation of PML bodies by full-length PML isoforms and their C-terminal domains in the presence and…”
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Photophysical Properties of BADAN Revealed in the Study of GGBP Structural Transitions by Fonin, Alexander V, Silonov, Sergey A, Antifeeva, Iuliia A, Stepanenko, Olga V, Stepanenko, Olesya V, Fefilova, Anna S, Povarova, Olga I, Gavrilova, Anastasia A, Kuznetsova, Irina M, Turoverov, Konstantin K

“…The fluorescent dye BADAN (6-bromoacetyl-2-dimetylaminonaphtalene) is widely used in various fields of life sciences, however, the photophysical properties of…”
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Folding of poly-amino acids and intrinsically disordered proteins in overcrowded milieu induced by pH change by Fonin, Alexander V., Stepanenko, Olga V., Sitdikova, Asiia K., Antifeeva, Iuliia A., Kostyleva, Elena I., Polyanichko, Alexander M., Karasev, Maksim M., Silonov, Sergey A., Povarova, Olga I., Kuznetsova, Irina M., Uversky, Vladimir N., Turoverov, Konstantin К.

“…pH-induced structural changes of the synthetic homopolypeptides poly-E, poly-K, poly-R, and intrinsically disordered proteins (IDPs) prothymosin α (ProTα) and…”
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On the Prevalence and Roles of Proteins Undergoing Liquid-Liquid Phase Separation in the Biogenesis of PML-Bodies by Silonov, Sergey A, Mokin, Yakov I, Nedelyaev, Eugene M, Smirnov, Eugene Y, Kuznetsova, Irina M, Turoverov, Konstantin K, Uversky, Vladimir N, Fonin, Alexander V

“…The formation and function of membrane-less organelles (MLOs) is one of the main driving forces in the molecular life of the cell. These processes are based on…”
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Structure and Conformational Properties of d-Glucose/d-Galactose-Binding Protein in Crowded Milieu by Fonin, Alexander V, Silonov, Sergey A, Sitdikova, Asiya K, Kuznetsova, Irina M, Uversky, Vladimir N, Turoverov, Konstantin K

“…Conformational changes of d-glucose/d-galactose-binding protein (GGBP) were studied under molecular crowding conditions modeled by concentrated solutions of…”
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Essential Role of Adhesion GPCR, GPR123, for Human Pluripotent Stem Cells and Reprogramming towards Pluripotency by Krasnova, Olga A, Kulakova, Karina A, Sopova, Julia V, Smirnov, Evgenyi Y, Silonov, Sergey A, Lomert, Ekaterina V, Bystrova, Olga A, Martynova, Marina G, Neganova, Irina E

“…G-protein-coupled receptors (GPCRs) are the largest family of cell surface receptors. They modulate key physiological functions and are required in diverse…”
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Biocompatible Re-Containing Block Copolymers for Intracellular pH Mapping in the PLIM Mode by Kisel, Kristina S., Baigildin, Vadim A., Mozzhukhina, Anna V., Zharskaia, Nina A., Silonov, Sergey A., Shakirova, Julia R., Tunik, Sergey P.

“…Monitoring of intracellular pH is of great importance since deviation of this parameter from the “normal” magnitudes can be considered as an indicator of…”
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Key role of cycloalkyne nature in alkyne-dye reagents for enhanced specificity of intracellular imaging by bioorthogonal bioconjugation by Vidyakina, Alexandra A, Silonov, Sergey A, Govdi, Anastasia I, Ivanov, Alexander Yu, Podolskaya, Ekaterina P, Balova, Irina A, Bräse, Stefan, Danilkina, Natalia A

“…Conjugates of benzothiophene-fused azacyclononyne BT9N-NH2 with fluorescent dyes were developed to visualise azidoglycans intracellularly. The significance of…”
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Biocompatible Phosphorescent Ir(III) Complexes for Hypoxia Sensing in PLIM Mode by Samandarsangari, Mozhgan, Zharskaia, Nina A., Silonov, Sergey A., Galenko, Ekaterina E., Karpitskaya, Daria O., Rück, Angelika, Kritchenkov, Ilya S., Tunik, Sergey P.

“…In this work, two new biscyclometalated Ir(III) complexes with diimine ligands were synthesized. The compounds were characterized by 1D and 2D NMR spectroscopy…”
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Folding perspectives of an intrinsically disordered transactivation domain and its single mutation breaking the folding propensity by Sharma, Nitin, Fonin, Alexander V., Shpironok, Olesya G., Silonov, Sergey A., Turoverov, Konstantin K., Uversky, Vladimir N., Kuznetsova, Irina M., Giri, Rajanish

“…Transcriptional regulation is a critical facet of cellular development controlled by numerous transcription factors, among which are E-proteins (E2A, HEB, and…”
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Photo-dependent membrane-less organelles formed from plant phyB and PIF6 proteins in mammalian cells by Fonin, Alexander V., Antifeeva, Iuliia A., Shpironok, Olesya G., Stepanenko, Olesya V., Silonov, Sergey A., Stepanenko, Olga V., Antifeev, Ivan E., Romanovich, Anna E., Kuznetsova, Irina M., Kim, Jeong-Il, Uversky, Vladimir N., Turoverov, Konstantin K.

“…Plant photobodies are the membrane-less organelles (MLOs) that can be generated by protein-protein interactions between active form of phytochrome B (phyB) and…”
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Phytochrome Photobodies in Mammalian Cells by Fonin, Alexander V., Antifeeva, Iuliia A., Shpironok, Olesya G., Stepanenko, Olesya, Silonov, Sergey A., Kuznetsova, Irina M., Turoverov, Konstantin K.

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PML-Bodies as Open Dynamic System by Silonov, Sergey A., Fonin, Alexander V., Shpironok, Olesya G., Antifeeva, Iuliia A., Kuznetsova, Irina M., Turoverov, Konstantin K.

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Spontaneous gradient copolymers of N-vinylsuccinimide/N-vinylsuccinamic acid with O-cholesteryl (meth)acrylate via RAFT polymerization as potential drug delivery systems by Levit, Mariia L., Sivtsov, Evgenii V., Sinitsyna, Ekaterina S., Bagaeva, Irina O., Dobrodumov, Anatolii V., Nikolaeva, Alexandra L., Zakharova, Natalia V., Gostev, Alexey I., Silonov, Sergey A., Gofman, Iosif V., Korzhikova-Vlakh, Evgenia G.

“…[Display omitted] •Novel gradient-like copolymers were synthesized by RAFT polymerization.•Copolymerization of N-vinylsuccinimide with O-cholesteryl…”
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