Search Results - "Sillevis Smitt, Peter A. E."

Low-grade glioma harbors few CD8 T cells, which is accompanied by decreased expression of chemo-attractants, not immunogenic antigens by Weenink, Bas, Draaisma, Kaspar, Ooi, Han Z., Kros, Johan M., Sillevis Smitt, Peter A. E., Debets, Reno, French, Pim J.

“…In multiple tumor types, prediction of response to immune therapies relates to the presence, distribution and activation state of tumor infiltrating…”
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IDH1 R132H decreases proliferation of glioma cell lines in vitro and in vivo by Bralten, Linda B. C., Kloosterhof, Nanne K., Balvers, Rutger, Sacchetti, Andrea, Lapre, Lariesa, Lamfers, Martine, Leenstra, Sieger, de Jonge, Hugo, Kros, Johan M., Jansen, Erwin E. W., Struys, Eduard A., Jakobs, Cornelis, Salomons, Gajja S., Diks, Sander H., Peppelenbosch, Maikel, Kremer, Andreas, Hoogenraad, Casper C., Sillevis Smitt, Peter A. E., French, Pim J.

“…Objective: A high percentage of grade II and III gliomas have mutations in the gene encoding isocitrate dehydrogenase (IDH1). This mutation is always a…”
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Proteomics comparison of cerebrospinal fluid of relapsing remitting and primary progressive multiple sclerosis by Stoop, Marcel P, Singh, Vaibhav, Dekker, Lennard J, Titulaer, Mark K, Stingl, Christoph, Burgers, Peter C, Sillevis Smitt, Peter A E, Hintzen, Rogier Q, Luider, Theo M

“…Based on clinical representation of disease symptoms multiple sclerosis (MScl) patients can be divided into two major subtypes; relapsing remitting (RR) MScl…”
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Serum Levels of Pregnancy Zone Protein are Elevated in Presymptomatic Alzheimer’s Disease by IJsselstijn, Linda, Dekker, Lennard J. M, Stingl, Christoph, van der Weiden, Marcel M, Hofman, Albert, Kros, Johan M, Koudstaal, Peter J, Sillevis Smitt, Peter A. E, Ikram, M. Arfan, Breteler, Monique M. B, Luider, Theo M

“…We have sought for disease-related proteins that could predict the onset of Alzheimer’s disease (AD) in a study population derived from the Rotterdam Scan…”
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Anti‐LGI1 encephalitis is strongly associated with HLA‐DR7 and HLA‐DRB4 by van Sonderen, Agnes, Roelen, Dave L., Stoop, Johannes A., Verdijk, Robert M., Haasnoot, Geert W., Thijs, Roland D., Wirtz, Paul W., Schreurs, Marco W. J., Claas, Frans H. J., Sillevis Smitt, Peter A. E., Titulaer, Maarten J.

“…Leucine‐rich glioma‐inactivated1 (LGI1) encephalitis is an antibody‐associated inflammation of the limbic area. An autoimmune etiology is suspected but not yet…”
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Incidence of early pseudo‐progression in a cohort of malignant glioma patients treated with chemoirradiation with temozolomide by Taal, Walter, Brandsma, Dieta, de Bruin, Hein G., Bromberg, Jacoline E., Swaak‐Kragten, Annemarie T., Sillevis Smitt, Peter A. E., van Es, Corine A., van den Bent, Martin J.

“…BACKGROUND. Radiotherapy (RT) plus concomitant and adjuvant temozolomide (TMZ) is now the standard of care for patients with newly diagnosed glioblastoma. The…”
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Addition of serum-containing medium to cerebrospinal fluid prevents cellular loss over time by de Graaf, Marieke T., van den Broek, Patricia D. M., Kraan, Jaco, Luitwieler, Ronald L., van den Bent, Martin J., Boonstra, Joke G., Schmitz, Paul I. M., Gratama, Jan W., Sillevis Smitt, Peter A. E.

“…Immediately after sampling, leukocyte counts in native cerebrospinal fluid (CSF) start to decrease rapidly. As the time lapse between CSF collection to…”
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Increased levels of circulating endothelial progenitor cells and circulating endothelial nitric oxide synthase in patients with gliomas by Zheng, Ping-Pin, Hop, Wim C., Luider, Theodorus M., Sillevis Smitt, Peter A. E., Kros, Johan M.

“…Objective Gliomas are among the highest vascularized tumors. We hypothesized that patients with gliomas have increased levels of circulating endothelial…”
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Treatment of large low-grade oligodendroglial tumors with upfront procarbazine, lomustine, and vincristine chemotherapy with long follow-up: a retrospective cohort study with growth kinetics by Taal, Walter, van der Rijt, Carin C. D., Dinjens, Winand N. M., Sillevis Smitt, Peter A. E., Wertenbroek, Agnes A. A. C. M., Bromberg, Jacoline E. C., van Heuvel, Irene, Kros, Johan M., van den Bent, Martin J.

“…We treated patients with newly diagnosed and large low-grade oligodendroglial tumors with upfront procarbazine, CCNU and vincristine (PCV) in order to delay…”
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Metabolic changes related to the IDH1 mutation in gliomas preserve TCA‐cycle activity: An investigation at the protein level by Dekker, Lennard J. M., Wu, Suying, Jurriëns, Cherise, Mustafa, Dana A. N., Grevers, Frederieke, Burgers, Peter C., Sillevis Smitt, Peter A. E., Kros, Johan M., Luider, Theo M.

“…The discovery of the IDH1 R132H (IDH1 mut) mutation in low‐grade glioma and the associated change in function of the IDH1 enzyme has increased the interest in…”
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Novel Antibody-Peptide Binding Assay Indicates Presence of Immunoglobulins against EGFR Phospho-Site S1166 in High-Grade Glioma by Zeneyedpour, Lona, Stingl, Christoph, Kros, Johan M, Sillevis Smitt, Peter A E, Luider, Theo M

“…We investigated the feasibility of detecting the presence of specific autoantibodies against potential tumor-associated peptide antigens by enriching these…”
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Quantitative Matrix-Assisted Laser Desorption Ionization−Fourier Transform Ion Cyclotron Resonance (MALDI−FT-ICR) Peptide Profiling and Identification of Multiple-Sclerosis-Related Proteins by Stoop, Marcel P, Dekker, Lennard J, Titulaer, Mark K, Lamers, Robert-Jan A. N, Burgers, Peter C, Sillevis Smitt, Peter A. E, van Gool, Alain J, Luider, Theo M, Hintzen, Rogier Q

“…We introduce a matrix-assisted laser desorption ionization−Fourier transform ion cyclotron resonance (MALDI−FT-ICR) method for quantitative peptide profiling,…”
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Dose dense 1 week on/1 week off temozolomide in recurrent glioma: a retrospective study by Taal, Walter, Segers-van Rijn, Joyce M. W., Kros, Johan M., van Heuvel, Irene, van der Rijt, Carin C. D., Bromberg, Jacoline E., Sillevis Smitt, Peter A. E., van den Bent, Martin J.

“…Alternative temozolomide regimens have been proposed to overcome O 6 -methylguanine-DNA methyltransferase mediated resistance. We investigated the efficacy and…”
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IDH1-mutated transgenic zebrafish lines: An in-vivo model for drug screening and functional analysis by Gao, Ya, de Wit, Maurice, Struys, Eduard A, van der Linde, Herma C Z, Salomons, Gajja S, Lamfers, Martine L M, Willemsen, Rob, Sillevis Smitt, Peter A E, French, Pim J

“…The gene encoding isocitrate dehydrogenase 1 (IDH1) is frequently mutated in several tumor types including gliomas. The most prevalent mutation in gliomas is a…”
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Immune Repertoire after Immunization As Seen by Next-Generation Sequencing and Proteomics by VanDuijn, Martijn M, Dekker, Lennard J, van IJcken, Wilfred F J, Sillevis Smitt, Peter A E, Luider, Theo M

“…The immune system produces a diverse repertoire of immunoglobulins in response to foreign antigens. During B-cell development, VDJ recombination and somatic…”
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Serum Clusterin Levels Are Not Increased in Presymptomatic Alzheimer’s Disease by IJsselstijn, Linda, Dekker, Lennard J. M, Koudstaal, Peter J, Hofman, Albert, Sillevis Smitt, Peter A. E, Breteler, Monique M. B, Luider, Theo M

“…Increased plasma levels of clusterin have recently been found to be associated with severity and progression in Alzheimer’s disease (AD). We have investigated…”
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Adherence to Analgesics in Oncology Outpatients: Focus on Taking Analgesics on Time by Oldenmenger, Wendy H., Sillevis Smitt, Peter A. E., Raaf, Pleun J., Rijt, Carin C. D.

“…Background Inadequate adherence to prescribed analgesics may be one of the reasons why patients with cancer experience unrelieved pain. Adherence is directly…”
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Anti-LGI1 encephalitis: Clinical syndrome and long-term follow-up by van Sonderen, Agnes, Thijs, Roland D, Coenders, Elias C, Jiskoot, Lize C, Sanchez, Esther, de Bruijn, Marienke A.A.M, van Coevorden-Hameete, Marleen H, Wirtz, Paul W, Schreurs, Marco W.J, Sillevis Smitt, Peter A.E, Titulaer, Maarten J

“…OBJECTIVE:This nationwide study gives a detailed description of the clinical features and long-term outcome of anti–leucine-rich glioma-inactivated 1 (LGI1)…”
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Evaluation of the new body fluid mode on the Sysmex XE-5000 for counting leukocytes and erythrocytes in cerebrospinal fluid and other body fluids by de Jonge, Robert, Brouwer, Rob, de Graaf, Marieke T, Luitwieler, Ronald L, Fleming, Cherina, de Frankrijker-Merkestijn, Magda, Sillevis Smitt, Peter A E, Boonstra, Joke G, Lindemans, Jan

“…We evaluated the body fluid (BF) mode on the new Sysmex XE-5000 analyzer. Red (RBC) and white blood cell (WBC) (differential) counts of BFs (139 patient…”
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The clinical spectrum of Caspr2 antibody–associated disease by van Sonderen, Agnes, Ariño, Helena, Petit-Pedrol, Mar, Leypoldt, Frank, Körtvélyessy, Peter, Wandinger, Klaus-Peter, Lancaster, Eric, Wirtz, Paul W, Schreurs, Marco W.J, Sillevis Smitt, Peter A.E, Graus, Francesc, Dalmau, Josep, Titulaer, Maarten J

“…OBJECTIVE:To report a large cohort of patients with antibodies against contactin-associated protein-like 2 (Caspr2) and provide the clinical spectrum of this…”
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