Search Results - "Sill, Heinz"

Inference of transcription factor binding from cell-free DNA enables tumor subtype prediction and early detection by Ulz, Peter, Perakis, Samantha, Zhou, Qing, Moser, Tina, Belic, Jelena, Lazzeri, Isaac, Wölfler, Albert, Zebisch, Armin, Gerger, Armin, Pristauz, Gunda, Petru, Edgar, White, Brandon, Roberts, Charles E. S., John, John St, Schimek, Michael G., Geigl, Jochen B., Bauernhofer, Thomas, Sill, Heinz, Bock, Christoph, Heitzer, Ellen, Speicher, Michael R.

“…Deregulation of transcription factors (TFs) is an important driver of tumorigenesis, but non-invasive assays for assessing transcription factor activity are…”
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Complex Tumor Genomes Inferred from Single Circulating Tumor Cells by Array-CGH and Next-Generation Sequencing by HEITZER, Ellen, AUER, Martina, HÖFLER, Gerald, EISNER, Florian, SILL, Heinz, SAMONIGG, Hellmut, PANTEL, Klaus, RIETHDORF, Sabine, BAUERNHOFER, Thomas, GEIGL, Jochen B, SPEICHER, Michael R, GASCH, Christin, PICHLER, Martin, ULZ, Peter, HOFFMANN, Eva Maria, LAX, Sigurd, WALDISPUEHL-GEIGL, Julie, MAUERMANN, Oliver, LACKNER, Carolin

“…Circulating tumor cells (CTC) released into blood from primary cancers and metastases reflect the current status of tumor genotypes, which are prone to…”
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Repeated fecal microbiota transplantations attenuate diarrhea and lead to sustained changes in the fecal microbiota in acute, refractory gastrointestinal graft- versus -host-disease by Spindelboeck, Walter, Schulz, Eduard, Uhl, Barbara, Kashofer, Karl, Aigelsreiter, Ariane, Zinke-Cerwenka, Wilma, Mulabecirovic, Adnan, Kump, Patrizia K, Halwachs, Bettina, Gorkiewicz, Gregor, Sill, Heinz, Greinix, Hildegard, Högenauer, Christoph, Neumeister, Peter

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Clinical implications of subclonal TP53 mutations in acute myeloid leukemia by Prochazka, Katharina T, Pregartner, Gudrun, Rücker, Frank G, Heitzer, Ellen, Pabst, Gabriel, Wölfler, Albert, Zebisch, Armin, Berghold, Andrea, Döhner, Konstanze, Sill, Heinz

“…The role of subclonal mutations, defined by a variant allele frequency of <20%, has not been addressed in acute myeloid leukemia yet. We, therefore, analyzed…”
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Therapeutic Resistance in Acute Myeloid Leukemia: The Role of Non-Coding RNAs by Zebisch, Armin, Hatzl, Stefan, Pichler, Martin, Wölfler, Albert, Sill, Heinz

“…Acute myeloid leukemia (AML) is caused by malignant transformation of hematopoietic stem or progenitor cells and displays the most frequent acute leukemia in…”
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RAF Kinase Inhibitor Protein in Myeloid Leukemogenesis by Zebisch, Armin, Caraffini, Veronica, Sill, Heinz

“…RAF kinase inhibitor protein (RKIP) is an essential regulator of intracellular signaling. A somatic loss of RKIP expression is a frequent event in solid human…”
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Downregulation of MTSS1 in acute myeloid leukemia is associated with a poor prognosis, chemotherapy resistance, and disease aggressiveness by Grandits, Alexander Michael, Nguyen, Chi Huu, Schlerka, Angela, Hackl, Hubert, Sill, Heinz, Etzler, Julia, Heyes, Elizabeth, Stoiber, Dagmar, Grebien, Florian, Heller, Gerwin, Wieser, Rotraud

“…Despite recent approval of targeted drugs for acute myeloid leukemia (AML) therapy, chemotherapy with cytosine arabinoside and anthracyclines remains an…”
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The TP53 Pro72Arg SNP in de novo acute myeloid leukemia by Schulz, Eduard, Sill, Heinz

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Contaminated handwashing sinks as the source of a clonal outbreak of KPC-2-producing Klebsiella oxytoca on a hematology ward by Leitner, Eva, Zarfel, Gernot, Luxner, Josefa, Herzog, Kathrin, Pekard-Amenitsch, Shiva, Hoenigl, Martin, Valentin, Thomas, Feierl, Gebhard, Grisold, Andrea J, Högenauer, Christoph, Sill, Heinz, Krause, Robert, Zollner-Schwetz, Ines

“…We investigated sinks as possible sources of a prolonged Klebsiella pneumonia carbapenemase (KPC)-producing Klebsiella oxytoca outbreak. Seven…”
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Phenotypic characterization of leukemia-initiating stem cells in chronic myelomonocytic leukemia by Eisenwort, Gregor, Sadovnik, Irina, Keller, Alexandra, Ivanov, Daniel, Peter, Barbara, Berger, Daniela, Stefanzl, Gabriele, Bauer, Karin, Slavnitsch, Katharina, Greiner, Georg, Gleixner, Karoline V., Sperr, Wolfgang R., Willmann, Michael, Sill, Heinz, Bettelheim, Peter, Geissler, Klaus, Deininger, Michael, Rülicke, Thomas, Valent, Peter

“…Chronic myelomonocytic leukemia (CMML) is a stem cell-derived neoplasm characterized by dysplasia, uncontrolled expansion of monocytes, and substantial risk to…”
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Somatic TP53 mutations characterize preleukemic stem cells in acute myeloid leukemia by Lal, Ridhima, Lind, Karin, Heitzer, Ellen, Ulz, Peter, Aubell, Kristina, Kashofer, Karl, Middeke, Jan M., Thiede, Christian, Schulz, Eduard, Rosenberger, Angelika, Hofer, Sybille, Feilhauer, Birgit, Rinner, Beate, Svendova, Vendula, Schimek, Michael G., Rücker, Frank G., Hoefler, Gerald, Döhner, Konstanze, Zebisch, Armin, Wölfler, Albert, Sill, Heinz

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EZH2 inactivation in RAS-driven myeloid neoplasms hyperactivates RAS-signaling and increases MEK inhibitor sensitivity by Berg, Johannes Lorenz, Perfler, Bianca, Hatzl, Stefan, Uhl, Barbara, Reinisch, Andreas, Pregartner, Gudrun, Berghold, Andrea, Penz, Thomas, Schuster, Michael, Geissler, Klaus, Prokesch, Andreas, Müller-Tidow, Carsten, Hoefler, Gerald, Kashofer, Karl, Wölfler, Albert, Sill, Heinz, Caraffini, Veronica, Zebisch, Armin

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Identification of CD25 as STAT5-Dependent Growth Regulator of Leukemic Stem Cells in Ph+ CML by Sadovnik, Irina, Hoelbl-Kovacic, Andrea, Herrmann, Harald, Eisenwort, Gregor, Cerny-Reiterer, Sabine, Warsch, Wolfgang, Hoermann, Gregor, Greiner, Georg, Blatt, Katharina, Peter, Barbara, Stefanzl, Gabriele, Berger, Daniela, Bilban, Martin, Herndlhofer, Susanne, Sill, Heinz, Sperr, Wolfgang R, Streubel, Berthold, Mannhalter, Christine, Holyoake, Tessa L, Sexl, Veronika, Valent, Peter

“…In chronic myelogenous leukemia (CML), leukemic stem cells (LSC) represent a critical target of therapy. However, little is known about markers and targets…”
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The role of germline mutation profiling in the selection of related donors for haematopoietic stem cell transplantation by Zebisch, Armin, Winter, Gerlinde, Kashofer, Karl, Hatzl, Stefan, Uhl, Barbara, Wurm, Sonja, Wölfler, Albert, Greinix, Hildegard T., Hoefler, Gerald, Sill, Heinz

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Detection of prognostically relevant mutations and translocations in myeloid sarcoma by next generation sequencing by Kashofer, Karl, Gornicec, Max, Lind, Karin, Caraffini, Veronica, Schauer, Silvia, Beham-Schmid, Christine, Wölfler, Albert, Hoefler, Gerald, Sill, Heinz, Zebisch, Armin

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Synergistic Targeting of the Regulatory and Catalytic Subunits of PI3Kδ in Mature B-cell Malignancies by Cooney, Jeffrey D, Lin, An-Ping, Jiang, Daifeng, Wang, Long, Suhasini, Avvaru N, Myers, Jamie, Qiu, ZhiJun, Wölfler, Albert, Sill, Heinz, Aguiar, Ricardo C T

“…Aberrant activation of the B-cell receptor (BCR) is implicated in the pathogenesis of mature B-cell tumors, a concept validated in part by the clinical success…”
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Comparison of acute myeloid leukemia and myelodysplastic syndromes with TP53 aberrations by Dutta, Sayantanee, Moritz, Jennifer, Pregartner, Gudrun, Thallinger, Gerhard G., Brandstätter, Ilona, Lind, Karin, Rezania, Simin, Lyssy, Freya, Reinisch, Andreas, Zebisch, Armin, Berghold, Andrea, Wölfler, Albert, Sill, Heinz

“…TP53 aberrations are found in approximately 10% of patients with acute myeloid leukemia (AML) and myelodysplastic syndromes (MDS) and are considered early…”
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A novel function of STAT3β in suppressing interferon response improves outcome in acute myeloid leukemia by Edtmayer, Sophie, Witalisz-Siepracka, Agnieszka, Zdársky, Bernhard, Heindl, Kerstin, Weiss, Stefanie, Eder, Thomas, Dutta, Sayantanee, Graichen, Uwe, Klee, Sascha, Sharif, Omar, Wieser, Rotraud, Győrffy, Balázs, Poli, Valeria, Casanova, Emilio, Sill, Heinz, Grebien, Florian, Stoiber, Dagmar

“…Signal transducer and activator of transcription 3 (STAT3) is frequently overexpressed in patients with acute myeloid leukemia (AML). STAT3 exists in two…”
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STAT3 in acute myeloid leukemia facilitates natural killer cell-mediated surveillance by Witalisz-Siepracka, Agnieszka, Denk, Clio-Melina, Zdársky, Bernhard, Hofmann, Lorenz, Edtmayer, Sophie, Harm, Theresa, Weiss, Stefanie, Heindl, Kerstin, Hessenberger, Manuel, Summer, Sabrina, Dutta, Sayantanee, Casanova, Emilio, Obermair, Gerald J, Győrffy, Balázs, Putz, Eva Maria, Sill, Heinz, Stoiber, Dagmar

“…Acute myeloid leukemia (AML) is a heterogenous disease characterized by the clonal expansion of myeloid progenitor cells. Despite recent advancements in the…”
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Publisher Correction: Inference of transcription factor binding from cell-free DNA enables tumor subtype prediction and early detection by Ulz, Peter, Perakis, Samantha, Zhou, Qing, Moser, Tina, Belic, Jelena, Lazzeri, Isaac, Wölfler, Albert, Zebisch, Armin, Gerger, Armin, Pristauz, Gunda, Petru, Edgar, White, Brandon, Roberts, Charles E. S., John, John St, Schimek, Michael G., Geigl, Jochen B., Bauernhofer, Thomas, Sill, Heinz, Bock, Christoph, Heitzer, Ellen, Speicher, Michael R.

“…An amendment to this paper has been published and can be accessed via a link at the top of the paper…”
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