Search Results - "Siliciano, Paul G"

Restoring species-specific posttransfer editing activity to a synthetase with a defunct editing domain by SternJohn, Julius, Hati, Sanchita, Siliciano, Paul G, Musier-Forsyth, Karin

“…Aminoacyl-tRNA synthetases are multidomain proteins responsible for the attachment of specific amino acids to their tRNA substrates. Prolyl-tRNA synthetases…”
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Evidence for an essential non-Watson-Crick interaction between the first and last nucleotides of a nuclear pre-mRNA intron by Parker, Roy, Siliciano, Paul G

“…Nuclear pre-messenger RNA splicing requires the action of five small nuclear (sn) RNAs, U1, U2, U4, U5 and U6, and more than 50 proteins. The mechanistic…”
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Pre-transfer editing by class II prolyl-tRNA synthetase: role of aminoacylation active site in "selective release" of noncognate amino acids by Hati, Sanchita, Ziervogel, Brigitte, Sternjohn, Julius, Wong, Fai-Chu, Nagan, Maria C, Rosen, Abbey E, Siliciano, Paul G, Chihade, Joseph W, Musier-Forsyth, Karin

“…Aminoacyl-tRNA synthetases catalyze the attachment of cognate amino acids to specific tRNA molecules. To prevent potential errors in protein synthesis caused…”
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yeast splicing factor Prp40p contains functional leucine-rich nuclear export signals that are essential for splicing by Murphy, M.W, Olson, B.L, Siliciano, P.G

“…To investigate the function of the essential U1 snRNP protein Prp40p, we performed a synthetic lethal screen in Saccharomyces cerevisiae. Using an allele of…”
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Pre-transfer Editing by Class II Prolyl-tRNA Synthetase by Hati, Sanchita, Ziervogel, Brigitte, SternJohn, Julius, Wong, Fai-Chu, Nagan, Maria C., Rosen, Abbey E., Siliciano, Paul G., Chihade, Joseph W., Musier-Forsyth, Karin

“…Aminoacyl-tRNA synthetases catalyze the attachment of cognate amino acids to specific tRNA molecules. To prevent potential errors in protein synthesis caused…”
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A diverse set of nuclear RNAs transfer between nuclei of yeast heterokaryons by Olson, Brian L., Siliciano, Paul G.

“…Small nuclear RNAs and small nucleolar RNAs function in the nucleus of eukaryotic cells during pre‐mRNA splicing and ribosomal RNA processing, respectively. In…”
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Recognition of the TACTAAC box during mRNA splicing in yeast involves base pairing to the U2-like snRNA by Parker, R, Siliciano, P G, Guthrie, C

“…The U2 snRNP binds to the site of branch formation during splicing of mammalian pre-mRNA in vitro. In Saccharomyces cerevisiae the branch site is within the…”
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Transcription and regulatory signals at the mating type locus in yeast by Siliciano, P G, Tatchell, K

“…The mating type locus with two alleles (MATa and MAT alpha) determines cell type in yeast by activating and repressing sets of cell-type-specific genes. The…”
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Saccharomyces cerevisiae has a U1-like small nuclear RNA with unexpected properties by Siliciano, P.G, Jones, M.H, Guthrie, C

“…Previous experiments indicated that only a small subset of the $\simeq $24 small nuclear RNAs (snRNAs) in Saccharomyces cerevisiae have binding sites for the…”
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Cloning of the dut (deoxyuridine triphosphatase) gene of Escherichia coli by Taylor, A F, Siliciano, P G, Weiss, B

“…Through the molecular cloning of DNA, cells were obtained that could produce a 300-fold increased level of deoxyuridine triphosphatase (dUTPase). First, lambda…”
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Identification of Prp40, a novel essential yeast splicing factor associated with the U1 small nuclear ribonucleoprotein particle by Kao, Hung-Ying, Siliciano, Paul G.

“…Article Usage Stats Services MCB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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More than half of yeast U1 snRNA is dispensabel for growth by Siliciano, Paul G., Kivens, Wendy J., Guthrie, Christine

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The interaction between the first and last intron nucleotides in the second step of pre-mRNA splicing is independent of other conserved intron nucleotides by Ruis, Brian L., Kivens, Wendy J., Siliciano, Paul G.

“…Virtually all pre-mRNA introns begin with the sequence / GU and end with AG/ (where / indicates a border between an exon and an Intron). We have previously…”
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Saccharomyces cerevisiae has a Ul-like small nuclear RNA with unexpected properties by SILICIANO, P. G, JONES, M. H, GUTHRIE, C

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RNA sequences upstream of the 3' splice site repress splicing of mutant yeast ACT1 introns by Kivens, W, Siliciano, P G

“…A yeast ACT1 intron in which both the first and last intron nucleotides are mutated, the /a-c/ intron, splices 10% as well as wild type. We selected for…”
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The amino-terminal domain of yeast U1-70K is necessary and sufficient for function by Hilleren, Patricia J., Kao, Hung-Ying, Siliciano, Paul G.

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yeast homolog of the U1 snRNP protein 70K is encoded by the SNP1 gene by Kao, H.Y, Siliciano, P.G

“…The product of the yeast SNP1 gene has high homology to two domains of the metazoan U1 snRNP protein 70K, which binds to stem/loop I of the U1 RNA. However,…”
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An essential snRNA from S. cerevisiae has properties predicted for U4, including interaction with a U6-like snRNA by Siliciano, P G, Brow, D A, Roiha, H, Guthrie, C

“…Three yeast snRNAs (snR20, snR7, and snR14) have been implicated in pre-mRNA splicing. snR20 and snR7 contain domains of homology to U2 and U5, respectively,…”
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Identification of the DNA Sequences Controlling the Expression of the MATα Locus of Yeast by Siliciano, Paul G., Tatchell, Kelly

“…We have excised a 28-base-pair DNA fragment from the MATα intergenic region and tested its ability to direct diploid-specific transcriptional repression. This…”
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Genetic Analysis of Small Nuclear RNAs in Saccharomyces cerevisiae: Viable Sextuple Mutant by Parker, Roy, Simmons, Trey, Shuster, Elizabeth O., Siliciano, Paul G., Guthrie, Christine

“…Saccharomyces cerevisiae contains at least 24 distinct small nuclear RNAs (snRNAs), several of which are known to be essential for viability and to participate…”
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