Search Results - "Silberger, Daniel J."
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Th22 Cells Are an Important Source of IL-22 for Host Protection against Enteropathogenic Bacteria
Published in Immunity (Cambridge, Mass.) (14-12-2012)“…Interleukin-22 (IL-22) is central to host protection against bacterial infections at barrier sites. Both innate lymphoid cells (ILCs) and T cells produce…”
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SARS-CoV-2 Infections in Vaccinated and Unvaccinated Populations in Camp Lemonnier, Djibouti, from April 2020 to January 2022
Published in Viruses (30-08-2022)“…The global pandemic caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has highlighted the disparity between developed and developing…”
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Insights into the environmental reservoir of pathogenic Vibrio parahaemolyticus using comparative genomics
Published in Frontiers in microbiology (24-03-2015)“…Vibrio parahaemolyticus is an aquatic halophilic bacterium that occupies estuarine and coastal marine environments, and is a leading cause of seafood-borne…”
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Batf stabilizes Th17 cell development via impaired Stat5 recruitment of Ets1‐Runx1 complexes
Published in The EMBO journal (17-04-2023)“…Although the activator protein‐1 (AP‐1) factor Batf is required for Th17 cell development, its mechanisms of action to underpin the Th17 program are…”
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Differential IL-2 expression defines developmental fates of follicular versus nonfollicular helper T cells
Published in Science (American Association for the Advancement of Science) (14-09-2018)“…In response to infection, naïve CD4 T cells differentiate into two subpopulations: T follicular helper (T ) cells, which support B cell antibody production,…”
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Preventing dysbiosis of the neonatal mouse intestinal microbiome protects against late-onset sepsis
Published in Nature medicine (01-11-2019)“…Late-onset sepsis (LOS) is thought to result from systemic spread of commensal microbes from the intestines of premature infants. Clinical use of probiotics…”
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IL-6 promotes the differentiation of a subset of naive CD8+ T cells into IL-21-producing B helper CD8+ T cells
Published in The Journal of experimental medicine (17-10-2016)“…IL-6 is known to contribute to the differentiation of CD4 T cells into different subsets of effector T helper cells. Less is known about the potential of IL-6…”
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A nonredundant role for T cell-derived interleukin 22 in antibacterial defense of colonic crypts
Published in Immunity (Cambridge, Mass.) (08-03-2022)“…Interleukin (IL)-22 is central to immune defense at barrier sites. We examined the contributions of innate lymphoid cell (ILC) and T cell-derived IL-22 during…”
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Batf Stabilizes the Th17 Cell Developmental Program through Impairment of Stat5-dependent Recruitment of Ets1-Runx1 Complexes
Published in The Journal of immunology (1950) (01-05-2022)“…The emergence of alternative CD4 T cell fates is controlled by transcriptional networks activated downstream of TCR and cytokine signaling inputs. Th17 cells…”
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Citrobacter rodentium: a model enteropathogen for understanding the interplay of innate and adaptive components of type 3 immunity
Published in Mucosal immunology (01-09-2017)“…Citrobacter rodentium is a natural murine intestinal pathogen that shares a core set of virulence factors with the related human pathogens enteropathogenic…”
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Batf promotes and stabilizes Th17 cell development by antagonizing the actions of STAT5
Published in The Journal of immunology (1950) (01-05-2019)“…T helper type 17 (Th17) cells secrete IL-17A, IL-17F, IL-21, and IL-22 cytokines and can provide protection against extracellular pathogens or promote certain…”
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Temporal changes in cellular sources of CXC chemokines control neutrophil recruitment during Citrobacter rodentium infection
Published in The Journal of immunology (1950) (01-05-2020)“…Enteropathogenic E. coli (EPEC) is one of the leading causes of diarrheal disease among children. Citrobacter rodentium (C.r) is a mouse model for EPEC and…”
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A Non-redundant Role for T cell-derived Interleukin 22 in Antibacterial Defense of Colonic Crypts
Published in Immunity (Cambridge, Mass.) (08-03-2022)“…Interleukin (IL)-22 is central to immune defense at barrier sites. We examined the contributions of innate lymphoid cell (ILC) and T cell-derived IL-22 during…”
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Differential IL-2 Expression Defines Developmental Fates of Follicular versus Non-follicular Helper T cells
Published in Science (American Association for the Advancement of Science) (14-09-2018)“…In response to infection, naïve CD4 + T cells differentiate into two types of helpers: T follicular helper (Tfh) cells, which support B-cell antibody…”
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