Search Results - "Silber, Rolf"

Mechanisms of infective endocarditis: pathogen–host interaction and risk states by Werdan, Karl, Dietz, Sebastian, Löffler, Bettina, Niemann, Silke, Bushnaq, Hasan, Silber, Rolf-Edgar, Peters, Georg, Müller-Werdan, Ursula

“…Key Points Infective endocarditis (IE) is a major challenge for clinicians and a considerable burden for health-care systems In high-income countries over the…”
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Obesity Induces Signs of Premature Cardiac Aging in Younger Patients: The Role of Mitochondria by NIEMANN, Bernd, YING CHEN, TESCHNER, Mirja, LING LI, SILBER, Rolf-Edgar, ROHRBACH, Susanne

“…The purpose of the present study was to investigate the influence of obesity on cardiac aging. Obesity is associated with an increased incidence of left…”
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Protein glycation — Between tissue aging and protection by Simm, Andreas, Müller, Beatrice, Nass, Norbert, Hofmann, Britt, Bushnaq, Hasan, Silber, Rolf-Edgar, Bartling, Babett

“…Non-enzymatic formation of advanced glycation endproducts (AGEs) is associated with degenerative diseases. Chronic accumulation of AGEs with age in tissues…”
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Caloric restriction delays cardiac ageing in rats: role of mitochondria by Niemann, Bernd, Chen, Ying, Issa, Hassan, Silber, Rolf-Edgar, Rohrbach, Susanne

“…Aims We tested whether long-term caloric restriction (CR) corrects pre-existing manifestations of cardiac ageing in rats. Methods and results The age-specific…”
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Statins potently reduce the cytokine‐mediated IL‐6 release in SMC/MNC cocultures by Loppnow, Harald, Zhang, Li, Buerke, Michael, Lautenschläger, Michael, Chen, Li, Frister, Adrian, Schlitt, Axel, Luther, Tanja, Song, Nan, Hofmann, Britt, Rose‐John, Stefan, Silber, Rolf‐Edgar, Müller‐Werdan, Ursula, Werdan, Karl

“…Inflammatory pathways are involved in the development of atherosclerosis. Interaction of vessel wall cells and invading monocytes by cytokines may trigger…”
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It’s all in our skin—Skin autofluorescence—A promising outcome predictor in cardiac surgery: A single centre cohort study by Hofmann, Britt, Gerull, Kristin Anja, Bloch, Katja, Riemer, Marcus, Erbs, Christian, Fröhlich, Anna, Richter, Sissy, Ehrhardt, Martin, Zitterbart, Christopher, Bartel, Friederike Fee, Siegel, Pauline, Wienke, Andreas, Silber, Rolf-Edgar, Simm, Andreas

“…Background The optimum risk score determining perioperative mortality and morbidity in cardiac surgery remains debated. Advanced glycation end products (AGEs)…”
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Positive impact of retrograde autologous priming in adult patients undergoing cardiac surgery: a randomized clinical trial by Hofmann, Britt, Kaufmann, Claudia, Stiller, Markus, Neitzel, Thomas, Wienke, Andreas, Silber, Rolf-Edgar, Treede, Hendrik

“…Adult cardiac surgery with extracorporeal circulation is known to be associated with increased risk of blood transfusion leading to adverse outcomes…”
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Alterations of protein expression of phospholamban, ZASP and plakoglobin in human atria in subgroups of seniors by Gergs, Ulrich, Mangold, Winnie, Langguth, Frank, Hatzfeld, Mechthild, Hauptmann, Steffen, Bushnaq, Hasan, Simm, Andreas, Silber, Rolf-Edgar, Neumann, Joachim

“…The mature mammalian myocardium contains composite junctions ( areae compositae ) that comprise proteins of adherens junctions as well as desmosomes. Mutations…”
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Amyloid-β oligomers in cerebrospinal fluid are associated with cognitive decline in patients with Alzheimer's disease by Santos, Alexander Navarrete, Ewers, Michael, Minthon, Lennart, Simm, Andreas, Silber, Rolf-Edgar, Blennow, Kaj, Prvulovic, David, Hansson, Oskar, Hampel, Harald

“…Oligomers of the amyloid-β peptide (Aβ) are thought to be the most toxic form of Aβ and are linked to the development of Alzheimer's disease (AD). Here, we…”
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Age-associated changes of extracellular matrix collagen impair lung cancer cell migration by Bartling, Babett, Desole, Maximilian, Rohrbach, Susanne, Silber, Rolf-Edgar, Simm, Andreas

“…Although advanced age is linked with an increased incidence of lung carcinomas, elderly patients develop fewer metastatic tumors than their younger…”
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Advanced glycation end product associated skin autofluorescence: A mirror of vascular function? by Hofmann, Britt, Adam, Anne-Catrin, Jacobs, Kathleen, Riemer, Marcus, Erbs, Christian, Bushnaq, Hasan, Simm, Andreas, Silber, Rolf-Edgar, Santos, Alexander Navarrete

“…Advanced glycation end products (AGEs) seem to be involved in aging as well as in the development of cardiovascular diseases. During aging, AGEs accumulate in…”
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The receptor for advanced glycation end-products supports lung tissue biomechanics by Al-Robaiy, Samiya, Weber, Bettina, Simm, Andreas, Diez, Claudius, Rolewska, Paulina, Silber, Rolf-Edgar, Bartling, Babett

“…The receptor for advanced glycation end-products (RAGE) and its soluble forms are predominantly expressed in lung but its physiological importance in this…”
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Subgroups of monocytes predict cardiovascular events in patients with coronary heart disease. The PHAMOS trial (Prospective Halle Monocytes Study) by Höpfner, Florian, Jacob, Marrit, Ulrich, Christof, Russ, Martin, Simm, Andreas, Silber, Rolf E., Girndt, Matthias, Noutsias, Michel, Werdan, Karl, Schlitt, Axel

“…Monocytes can be differentiated by the presence of CD14 and CD16 (CD14++CD16-, classical; CD14++CD16+, intermediate and CD14 + CD16++, non-classical…”
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Glycation of extracellular matrix proteins impairs migration of immune cells by Haucke, Elisa, Navarrete-Santos, Alexander, Simm, Andreas, Silber, Rolf-Edgar, Hofmann, Britt

“…The immune response during aging and diabetes is disturbed and may be due to the altered migration of immune cells in an aged tissue. Our study should prove…”
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Prognostic Factors and Survival after Pulmonary Resection of Metastatic Renal Cell Carcinoma by Hofmann, Hans-Stefan, Neef, Heinz, Krohe, Katharina, Andreev, Petko, Silber, Rolf-Edgar

“…Pulmonary metastasectomy as well as immunotherapy have reproducible, albeit limited efficacy in advanced renal cell carcinoma (RCC). We examined whether…”
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Carotid to Femoral Pulse Wave Velocity Reflects the Extent of Coronary Artery Disease by Hofmann, Britt, Riemer, Marcus, Erbs, Christian, Plehn, Alexander, Navarrete Santos, Alexander, Wienke, Andreas, Silber, Rolf‐Edgar, Simm, Andreas

“…Arterial stiffness is a well‐established risk factor for cardiovascular disease and mortality. Carotid to femoral pulse wave velocity (cfPWV) as a measure of…”
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Potential biomarkers of ageing by Simm, Andreas, Nass, Norbert, Bartling, Babett, Hofmann, Britt, Silber, Rolf-Edgar, Navarrete Santos, Alexander

“…Life span in individual humans is very heterogeneous.Thus, the ageing rate, measured as the decline of functional capacity and stress resistance, is different…”
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Glycation of PDGF results in decreased biological activity by Nass, Norbert, Vogel, Katrin, Hofmann, Britt, Presek, Peter, Silber, Rolf-Edgar, Simm, Andreas

“…Advanced glycation end products (AGEs) are formed by the non-enzymatic glycation of proteins by reducing carbohydrates or α-oxo-aldehydes such as glyoxal and…”
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Down-regulation of the receptor for advanced glycation end-products (RAGE) supports non-small cell lung carcinoma by Bartling, Babett, Hofmann, Hans-Stefan, Weigle, Bernd, Silber, Rolf-Edgar, Simm, Andreas

“…The receptor for advanced glycation end-products (RAGE) is a transmembrane receptor of the immunoglobulin superfamily. Several ligands binding to RAGE have…”
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Age and obesity-associated changes in the expression and activation of components of the AMPK signaling pathway in human right atrial tissue by Niemann, Bernd, Pan, Ruping, Teschner, Mirja, Boening, Andreas, Silber, Rolf-Edgar, Rohrbach, Susanne

“…Obesity is associated with an increased incidence of left ventricular hypertrophy, diastolic dysfunction, heart failure, and premature cardiac aging. In the…”
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