Search Results - "Silbajoris, R"

Inhibition of protein tyrosine phosphatase activity mediates epidermal growth factor receptor signaling in human airway epithelial cells exposed to Zn2 by TAL, T. L, GRAVES, L. M, SILBAJORIS, R, BROMBERG, P. A, WU, W, SAMET, J. M

“…Epidemiological studies have implicated zinc (Zn2+) in the toxicity of ambient particulate matter (PM) inhalation. We previously showed that exposure to…”
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Reduced inspiratory flow attenuates IL-8 release and MAPK activation of lung overstretch by Kotani, M, Kotani, T, Li, Z, Silbajoris, R, Piantadosi, C.A, Huang, Y-C.T

“…Lung overstretch involves mechanical factors, including large tidal volumes (VT), which induce inflammatory responses. The current authors hypothesised that…”
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Mechanical ventilation of rat lung: effect on surfactant forms by Savov, J, Silbajoris, R, Young, S L

“…Mechanical ventilation of the lung could affect surfactant turnover by alteration of its secretion, recycling, and degradation. In vitro studies of surfactant…”
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IN VIVO AND IN VITRO CORRELATION OF PULMONARY MAP KINASE ACTIVATION FOLLOWING METALLIC EXPOSURE by Robert Silbajoris, Andrew J. Ghio, James M. Samet, Richard Jaskot, Kevin L. Dreher, Luisa E. Brighton

“…Residual oil fly ash (ROFA) is a particulate pollutant produced in the combustion of fuel oil. Exposure to ROFA is associated with adverse respiratory effects…”
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ACTIVATION OF EGF RECEPTORS MEDIATES PULMONARY VASOCONSTRICTION INDUCED BY RESIDUAL OIL FLY ASH by Huang, Yuh-Chin T., Wu, Weidong, Ghio, Andrew J., Carter, Jacqueline D., Silbajoris, Robert, Devlin, Robert B., Samet, James M.

“…Residual oil fly ash (ROFA)is a constituent of pollutant particles that can producelung injury and activate protein tyrosine phosphorylation cascade. In this…”
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Surfactant apoprotein in adult rat lung compartments is increased by dexamethasone by Young, S L, Ho, Y S, Silbajoris, R A

“…The distribution of the major surfactant apoprotein (SP-A) in adult rat lung was determined in order to gain insight into its metabolism, including packaging…”
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Dexamethasone increases adult rat lung surfactant lipids by Young, S L, Silbajoris, R

“…Prenatal administration of glucocorticoids stimulates epithelial cell maturation and induces a precocious development of pulmonary surfactant. The response of…”
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A48 AIR POLLUTION: MECHANISMS AND GLOBAL IMPACT: The Ubiquitous Pm Component Zinc Induces Ho-1 Expression Through Multiple Targets In The Nrf2/keap1 Signaling Pathway by Silbajoris, R, Wages, P, Speen, A, Dailey, L A, Simmons, S, Bromberg, P A, Samet, J M

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TLR-2 is involved in airway epithelial cell response to air pollution particles by Becker, Susanne, Dailey, Lisa, Soukup, Joleen M., Silbajoris, Robert, Devlin, Robert B.

“…Primary cultures of normal human airway epithelial cells (NHBE) respond to ambient air pollution particulate matter (PM) by increased production of the…”
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Ontogeny of rat lung type II cells correlated with surfactant lipid and surfactant apoprotein expression by Randell, S H, Silbajoris, R, Young, S L

“…During the last stages of intrauterine growth, remarkable changes occur in the alveolar epithelium that include cellular differentiation and increased…”
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Inhibition of protein tyrosine phosphatase activity mediates epidermal growth factor receptor signaling in human airway epithelial cells exposed to Zn{sup 2+} by Tal, T.L., Graves, L.M., Silbajoris, R., Bromberg, P.A., Wu, W., Samet, J.M.

“…Epidemiological studies have implicated zinc (Zn{sup 2+}) in the toxicity of ambient particulate matter (PM) inhalation. We previously showed that exposure to…”
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Biologic Effects of Oil Fly Ash by Ghio, Andrew J., Silbajoris, Robert, Carson, Johnny L., Samet, James M.

“…Epidemiologic studies have demonstrated increased human morbidity and mortality with elevations in the concentration of ambient air particulate matter (PM)…”
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Type II cell response to chronic beta adrenergic agonist and antagonist infusions by Young, S L, Silbajoris, R A

“…Beta adrenergic agonists stimulate the secretion of lamellar bodies by lung alveolar type II cells. Most studies of such stimuli have been for short time…”
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Alterations of surfactant pools in fetal and newborn rat lungs by SPAIN, C. L, SILBAJORIS, R, YOUNG, S. L

“…Preparation by the developing alveolar epithelium for the transition to air breathing and surfactant secretion at birth are critical components of neonatal…”
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Ultrafine carbon particles induce interleukin-8 gene transcription and p38 MAPK activation in normal human bronchial epithelial cells by Kim, Yu-Mee, Reed, William, Lenz, Anke G, Jaspers, Ilona, Silbajoris, Robert, Nick, Harry S, Samet, James M

“…Epidemiological studies suggest that ultrafine particles contribute to particulate matter-induced adverse health effects. Interleukin (IL)-8 is an important…”
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Regulation of cyclooxygenase-2 expression by cAMP response element and mRNA stability in a human airway epithelial cell line exposed to zinc by Wu, Weidong, Silbajoris, Robert A., Cao, Dongsun, Bromberg, Philip A., Zhang, Qiao, Peden, David B., Samet, James M.

“…Exposure to zinc-laden particulate matter in ambient and occupational settings has been associated with proinflammatory responses in the lung. Cyclooxygenase…”
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Acute Ozone-Induced Differential Gene Expression Profiles in Rat Lung by Nadadur, Srikanth S., Costa, Daniel L., Slade, Ralph, Silbjoris, Robert, Hatch, Gary E.

“…Ozone is an oxidant gas that can directly induce lung injury. Knowledge of the initial molecular events of the acute O3response would be useful in developing…”
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Inhibition of protein tyrosine phosphatase activity mediates epidermal growth factor receptor signaling in human airway epithelial cells exposed to Zn super(2) super(+) by Tal, T L, Graves, L M, Silbajoris, R, Bromberg, P A, Wu, W, Samet, J M

“…Epidemiological studies have implicated zinc (Zn super(2) super(+)) in the toxicity of ambient particulate matter (PM) inhalation. We previously showed that…”
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Transcription Factor Activation Following Exposure of an Intact Lung Preparation to Metallic Particulate Matter by Samet, James M., Silbajoris, Robert, Huang, Tony, Jaspers, Ilona

“…Metallic constituents contained in ambient particulate matter have been associated with adverse effects in a number of epidemiologic, in vitro, and in vivo…”
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Tyrosine phosphatases as targets in metal-induced signaling in human airway epithelial cells by Samet, J M, Silbajoris, R, Wu, W, Graves, L M

“…We previously showed that exposure to metal-laden combustion particles disregulates protein tyrosine phosphate homeostasis in human airway epithelial cells…”
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