Search Results - "Sikora, Andrea"

Cluster analysis driven by unsupervised latent feature learning of medications to identify novel pharmacophenotypes of critically ill patients by Sikora, Andrea, Jeong, Hayoung, Yu, Mengyun, Chen, Xianyan, Murray, Brian, Kamaleswaran, Rishikesan

“…Unsupervised clustering of intensive care unit (ICU) medications may identify unique medication clusters (i.e., pharmacophenotypes) in critically ill adults…”
Get full text

Long-Term Retention of Advanced Cardiovascular Life Support Knowledge and Confidence in Doctor of Pharmacy Students by Smith, Susan E, Sikora, Andrea N, Fulford, Michael, Rogers, Kelly C

“…This study aimed to evaluate the impact of American Heart Association (AHA) advanced cardiovascular life support (ACLS) education and training on long-term…”
Get full text

Beta-Adrenergic Blockade in Critical Illness by Bruning, Rebecca, Dykes, Hannah, Jones, Timothy W., Wayne, Nathaniel B., Sikora Newsome, Andrea

“…Catecholamine upregulation is a core pathophysiological feature in critical illness. Sustained catecholamine β-adrenergic induction produces adverse effects…”
Get full text

Validation of Prognostic Club Cell Secretory Protein (CC16) Cut-point in an Independent ALTA Cohort by Almuntashiri, Sultan, Chase, Aaron, Sikora, Andrea, Zhang, Duo

“…Background: Club cell secretory protein (CC16) has demonstrated utility as a lung-specific biomarker in predicting mortality in acute respiratory distress…”
Get full text

Pharmacist perceptions of CliftonStrengths® themes important for success in advanced cardiovascular life support by Smith, Susan E., Ayers, Parisa, Sikora Newsome, Andrea, Logan, Linda D., Fulford, Michael

“…What is known and objective Advanced Cardiovascular Life Support (ACLS) is an integrated, team‐based approach to optimizing patient outcomes during acute…”
Get full text

Plasma matrix metalloproteinase-3 predicts mortality in acute respiratory distress syndrome: a biomarker analysis of a randomized controlled trial by Jones, Timothy W, Almuntashiri, Sultan, Chase, Aaron, Alhumaid, Abdullah, Somanath, Payaningal R, Sikora, Andrea, Zhang, Duo

“…Matrix metalloproteinase-3 (MMP-3) is a proteolytic enzyme involved in acute respiratory distress syndrome (ARDS) pathophysiology that may serve as a…”
Get full text

Comparison of Inotropes for Use With the Impella Device in Cardiogenic Shock by Sulejmani, Essilvo, Wayne, Nathaniel, Provost, Laura, Chase, Aaron, Sikora, Andrea

Get full text

Machine learning vs. traditional regression analysis for fluid overload prediction in the ICU by Sikora, Andrea, Zhang, Tianyi, Murphy, David J., Smith, Susan E., Murray, Brian, Kamaleswaran, Rishikesan, Chen, Xianyan, Buckley, Mitchell S., Rowe, Sandra, Devlin, John W.

“…Fluid overload, while common in the ICU and associated with serious sequelae, is hard to predict and may be influenced by ICU medication use. Machine learning…”
Get full text

Pharmacophenotype identification of intensive care unit medications using unsupervised cluster analysis of the ICURx common data model by Sikora, Andrea, Rafiei, Alireza, Rad, Milad Ghiasi, Keats, Kelli, Smith, Susan E, Devlin, John W, Murphy, David J, Murray, Brian, Kamaleswaran, Rishikesan

“…Identifying patterns within ICU medication regimens may help artificial intelligence algorithms to better predict patient outcomes; however, machine learning…”
Get full text

449 Does incorporation of plasma biomarkers to the Lung Injury Prediction Score improve the predictive value for development of acute respiratory distress syndrome? by Chase, Aaron, Almuntashiri, Sultan, Bennett, Andrew, Sikora, Andrea, Zhang, Duo

“…OBJECTIVES/GOALS: To determine if incorporating specific laboratory values and plasma biomarkers (club cell secretory protein (CC16), matrix metalloproteinase…”
Get full text

Comment on Gross and MacDougall “Roles of the clinical pharmacist during the COVID‐19 pandemic” by Barlow, Brooke, Barlow, Ashley, Newsome, Andrea Sikora

Get full text

Evaluation of medication regimen complexity as a predictor for mortality by Sikora, Andrea, Devlin, John W., Yu, Mengyun, Zhang, Tianyi, Chen, Xianyan, Smith, Susan E., Murray, Brian, Buckley, Mitchell S., Rowe, Sandra, Murphy, David J.

“…While medication regimen complexity, as measured by a novel medication regimen complexity-intensive care unit (MRC-ICU) score, correlates with baseline…”
Get full text

Pharmacological Inhibition of MMP3 as a Potential Therapeutic Option for COVID-19 Associated Acute Respiratory Distress Syndrome by Kadry, Rana, Newsome, Andrea Sikora, Somanath, Payaningal R

“…The high mortality of coronavirus disease 2019 (COVID-19) patients is due to their progression to cytokine-associated organ injuries, primarily the acute…”
Get more information

Plasma TIMP-1 as a sex-specific biomarker for acute lung injury by Almuntashiri, Sultan, Jones, Timothy W, Wang, Xiaoyun, Sikora, Andrea, Zhang, Duo

“…Acute respiratory distress syndrome (ARDS) confers high morbidity and mortality, with a death rate reaching 40%. Pre-clinical and clinical studies have cited…”
Get full text

Cisatracurium attenuates LPS-induced modulation of MMP3 and junctional protein expression in human microvascular endothelial cells by Kadry, Rana W., Adil, Mir S., Newsome, Andrea Sikora, Somanath, Payaningal R.

“…Acute respiratory distress syndrome (ARDS) is a life-threatening form of acute lung injury (ALI) associated with hypoxemic lung damage and inflammation. Matrix…”
Get full text

Reverse Triggering: An Introduction to Diagnosis, Management, and Pharmacologic Implications by Murray, Brian, Sikora, Andrea, Mock, Jason R., Devlin, Thomas, Keats, Kelli, Powell, Rebecca, Bice, Thomas

“…Reverse triggering is an underdiagnosed form of patient-ventilator asynchrony in which a passive ventilator-delivered breath triggers a neural response…”
Get full text

Club Cell Secretory Protein-Derived Acute Respiratory Distress Syndrome Phenotypes Predict 90-Day Mortality: A Reanalysis of the Fluids and Catheter Treatment Trial by Chase, Aaron, Almuntashiri, Sultan, Sikora, Andrea, Zhang, Duo

“…Club cell secretory protein (CC16) is a protein with potential utility as a lung-specific biomarker for acute respiratory distress syndrome. The purpose of…”
Get full text

Major publications in critical care pharmacotherapy literature in 2018 by Newsome, Andrea Sikora, Bissell, Brittany D., Burry, Lisa D., Defayette, Aubrey A., Gagnon, David J., Gilbert, Brian W., Kramer, C. Joseph, Miller, Christopher J., Semanco, Michael, Smith, Melanie N., Hammond, Drayton A.

“…To summarize selected original critical care pharmacotherapy research published in 2018. The Critical Care Pharmacotherapy Literature Update (CCPLU) Group…”
Get full text

Major publications in the critical care pharmacotherapy literature: 2019 by Condeni, Melanie Smith, Basting, Alyson T., Costello, Patrick G., DePriest, Ashley, Eriksson, Evert A., Evans, Heather, Hertel, Kristie, Holder, Andre L., Kester, Alyssa N., Kowalski, Kinsey R., Bell, Carolyn Magee, McLean, Barbara, Reichert, Michael, Santibañez, Melissa, Wieruszewski, Patrick M., Newsome, Andrea Sikora

“…To summarize selected meta-analyses and trials related to critical care pharmacotherapy published in 2019. The Critical Care Pharmacotherapy Literature Update…”
Get full text

Early Diuretics for De-resuscitation in Septic Patients With Left Ventricular Dysfunction by Jones, Timothy W, Chase, Aaron M, Bruning, Rebecca, Nimmanonda, Naphun, Smith, Susan E, Sikora, Andrea

“…Introduction: De-resuscitation practices in septic patients with heart failure (HF) are not well characterized. This study aimed to determine if diuretic…”
Get full text