Search Results - "Sikkink, Robert A"

Identification of Gene Mutations in Autosomal Dominant Polycystic Kidney Disease through Targeted Resequencing by ROSSETTI, Sandro, HOPP, Katharina, HARRIS, Peter C, SIKKINK, Robert A, SUNDSBAK, Jamie L, YEAN KIT LEE, KUBLY, Vickie, ECKLOFF, Bruce W, WARD, Christopher J, WINEARLS, Christopher G, TORRES, Vicente E

“…Mutations in two large multi-exon genes, PKD1 and PKD2, cause autosomal dominant polycystic kidney disease (ADPKD). The duplication of PKD1 exons 1-32 as six…”
Get full text

Failure of Calcineurin Inhibitors to Prevent Pressure-Overload Left Ventricular Hypertrophy in Rats by Zhang, Weiguo, Kowal, Robert C, Rusnak, Frank, Sikkink, Robert A, Olson, Eric N, Victor, Ronald G

“…A rapidly emerging body of literature implicates a pivotal role for the Ca phosphatase calcineurin as a cellular target for a variety of Ca signaling pathways…”
Get full text

Mate Pair Sequencing of Whole-Genome-Amplified DNA Following Laser Capture Microdissection of Prostate Cancer by MURPHY, Stephen J, CHEVILLE, John C, ZAREI, Shabnam, JOHNSON, Sarah H, SIKKINK, Robert A, KOSARI, Farhad, FELDMAN, Andrew L, ECKLOFF, Bruce W, JEFFREY KARNES, R, VASMATZIS, George

“…High-throughput next-generation sequencing provides a revolutionary platform to unravel the precise DNA aberrations concealed within subgroups of tumour cells…”
Get full text

Clinical validation of a haplotyping method with next-generation sequencing by Cradic, Kendall W, Murphy, Stephen J, Sikkink, Robert A, Neuhauser, Claudia, Vasmatzis, George, Grebe, Stefan K G

“…Particularly problematic are recessive genes for which compound heterozygosity is relatively common, such as CYP21A2 (cytochrome P450, family 21, subfamily A,…”
Get full text

A simple method for gene phasing using mate pair sequencing by Cradic, Kendall W, Murphy, Stephen J, Drucker, Travis M, Sikkink, Robert A, Eberhardt, Norman L, Neuhauser, Claudia, Vasmatzis, George, Grebe, Stefan K G

“…Recessive genes cause disease when both copies are affected by mutant loci. Resolving the cis/trans relationship of variations has been an important problem…”
Get full text

Draft Genome Sequences of Nine Pseudomonas aeruginosa Strains, Including Eight Clinical Isolates by Jeraldo, Patricio, Cunningham, Scott A, Quest, Daniel, Sikkink, Robert A, O'Brien, Daniel, Eckloff, Bruce W, Patel, Robin, Chia, Nicholas

“…We report on nine draft genomes of Pseudomonas aeruginosa isolates, assembled using a hybrid paired-end and Nextera mate-pair library approach. Eight are of…”
Get full text

Inhibition of Calcineurin Phosphatase Activity by a Calcineurin B Homologous Protein by Lin, X, Sikkink, R A, Rusnak, F, Barber, D L

“…Calcineurin, a Ca 2+ /calmodulin-stimulated protein phosphatase, plays a key role in T-cell activation by regulating the activity of NFAT ( n uclear f actor of…”
Get full text

Identification of the High Affinity Mn2+ Binding Site of Bacteriophage λ Phosphoprotein Phosphatase:  Effects of Metal Ligand Mutations on Electron Paramagnetic Resonance Spectra and Phosphatase Activities by White, Daniel J, Reiter, Nicholas J, Sikkink, Robert A, Yu, Lian, Rusnak, Frank

“…Bacteriophage λ phosphoprotein phosphatase (λPP) has structural similarity to the mammalian Ser/Thr phosphoprotein phosphatases (PPPs) including the…”
Get full text

Contribution of neelaredoxin to oxygen tolerance by Treponema pallidum by Hazlett, Karsten R O, Cox, David L, Sikkink, Robert A, Auch'ere, Françoise, Rusnak, Frank, Radolf, Justin D

Get more information

Identification of the High Affinity Mn 2+ Binding Site of Bacteriophage λ Phosphoprotein Phosphatase:  Effects of Metal Ligand Mutations on Electron Paramagnetic Resonance Spectra and Phosphatase Activities by White, Daniel J., Reiter, Nicholas J., Sikkink, Robert A., Yu, Lian, Rusnak, Frank

Get full text

Development of anti-bovine thrombin antibodies following neurosurgical procedures by Diez-Martin, J, Sikkink, R A, Gilchrist, G S, Bowie, E J, Fass, D N

Get more information