Search Results - "Sikkema, William K A"

Inducible lung epithelial resistance requires multisource reactive oxygen species generation to protect against bacterial infections by Ware, Hayden H, Kulkarni, Vikram V, Wang, Yongxing, Pantaleón García, Jezreel, Leiva Juarez, Miguel, Kirkpatrick, Carson T, Wali, Shradha, Syed, Sarah, Kontoyiannis, Alexander D, Sikkema, William K A, Tour, James M, Evans, Scott E

“…Pneumonia remains a global health threat, in part due to expanding categories of susceptible individuals and increasing prevalence of antibiotic resistant…”
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Mechanistic Study of the Conversion of Superoxide to Oxygen and Hydrogen Peroxide in Carbon Nanoparticles by Jalilov, Almaz S, Zhang, Chenhao, Samuel, Errol L. G, Sikkema, William K. A, Wu, Gang, Berka, Vladimir, Kent, Thomas A, Tsai, Ah-Lim, Tour, James M

“…Hydrophilic carbon clusters (HCCs) are oxidized carbon nanoparticles with a high affinity for electrons. The electron accepting strength of HCCs, employing the…”
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Passive Anti-Icing and Active Deicing Films by Wang, Tuo, Zheng, Yonghao, Raji, Abdul-Rahman O, Li, Yilun, Sikkema, William K. A, Tour, James M

“…Anti-icing and deicing are the two major pathways for suppressing adhesion of ice on surfaces, yet materials with dual capabilities are rare. In this work, we…”
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Regulation of mitotic cytoskeleton dynamics and cytokinesis by integrin-linked kinase in retinoblastoma cells by Sikkema, William K A, Strikwerda, Arend, Sharma, Manju, Assi, Kiran, Salh, Baljinder, Cox, Michael E, Mills, Julia

“…During cell division integrin-linked kinase (ILK) has been shown to regulate microtubule dynamics and centrosome clustering, processes involved in cell cycle…”
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Highly Oxidized Graphene Quantum Dots from Coal as Efficient Antioxidants by Nilewski, Lizanne, Mendoza, Kimberly, Jalilov, Almaz S, Berka, Vladimir, Wu, Gang, Sikkema, William K. A, Metzger, Andrew, Ye, Ruquan, Zhang, Rui, Luong, Duy Xuan, Wang, Tuo, McHugh, Emily, Derry, Paul J, Samuel, Errol Loïc, Kent, Thomas A, Tsai, Ah-Lim, Tour, James M

“…Graphene quantum dots (GQDs) have recently been employed in various fields including medicine as antioxidants, primarily because of favorable biocompatibility…”
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Anti-frameshifting Ligand Reduces the Conformational Plasticity of the SARS Virus Pseudoknot by Ritchie, Dustin B, Soong, Jingchyuan, Sikkema, William K. A, Woodside, Michael T

“…Programmed −1 ribosomal frameshifting (−1 PRF) stimulated by mRNA pseudoknots regulates gene expression in many viruses, making pseudoknots potential targets…”
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Catalytic oxidation and reduction reactions of hydrophilic carbon clusters with NADH and cytochrome C: features of an electron transport nanozyme by Derry, Paul J, Nilewski, Lizanne G, Sikkema, William K A, Mendoza, Kimberly, Jalilov, Almaz, Berka, Vladimir, McHugh, Emily A, Tsai, Ah-Lim, Tour, James M, Kent, Thomas A

“…Previously, our group reported on the promising efficacy of poly(ethylene glycol)-hydrophilic carbon clusters (PEG-HCCs) to work as broadly active and high…”
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Conformational dynamics of the frameshift stimulatory structure in HIV-1 by Ritchie, Dustin B, Cappellano, Tonia R, Tittle, Collin, Rezajooei, Negar, Rouleau, Logan, Sikkema, William K A, Woodside, Michael T

“…Programmed ribosomal frameshifting (PRF) in HIV-1 is thought to be stimulated by a hairpin in the mRNA, although a pseudoknot-like triplex has also been…”
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Efficacy of Novel Carbon Nanoparticle Antioxidant Therapy in a Severe Model of Reversible Middle Cerebral Artery Stroke in Acutely Hyperglycemic Rats by Fabian, Roderic H, Derry, Paul J, Rea, Harriett Charmaine, Dalmeida, William V, Nilewski, Lizanne G, Sikkema, William K A, Mandava, Pitchaiah, Tsai, Ah-Lim, Mendoza, Kimberly, Berka, Vladimir, Tour, James M, Kent, Thomas A

“…While oxidative stress can be measured during transient cerebral ischemia, antioxidant therapies for ischemic stroke have been clinically unsuccessful. Many…”
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Erratum for Kirkpatrick et al., "Inducible Lung Epithelial Resistance Requires Multisource Reactive Oxygen Species Generation To Protect against Viral Infections" by Kirkpatrick, Carson T, Wang, Yongxing, Leiva Juarez, Miguel M, Shivshankar, Pooja, Pantaleón García, Jezreel, Plumer, Alexandria K, Kulkarni, Vikram V, Ware, Hayden H, Gulraiz, Fahad, Chavez Cavasos, Miguel A, Martinez Zayas, Gabriela, Wali, Shradha, Rice, Andrew P, Liu, Hongbing, Tour, James M, Sikkema, William K A, Cruz Solbes, Ana S, Youker, Keith A, Tuvim, Michael J, Dickey, Burton F, Evans, Scott E

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Antioxidant Carbon Nanoparticles Inhibit Fibroblast-Like Synoviocyte Invasiveness and Reduce Disease Severity in a Rat Model of Rheumatoid Arthritis by Tanner, Mark R, Huq, Redwan, Sikkema, William K A, Nilewski, Lizanne G, Yosef, Nejla, Schmitt, Cody, Flores-Suarez, Carlos P, Raugh, Arielle, Laragione, Teresina, Gulko, Pércio S, Tour, James M, Beeton, Christine

“…Reactive oxygen species have been involved in the pathogenesis of rheumatoid arthritis (RA). Our goal was to determine the effects of selectively scavenging…”
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Preferential uptake of antioxidant carbon nanoparticles by T lymphocytes for immunomodulation by Huq, Redwan, Samuel, Errol L. G., Sikkema, William K. A., Nilewski, Lizanne G., Lee, Thomas, Tanner, Mark R., Khan, Fatima S., Porter, Paul C., Tajhya, Rajeev B., Patel, Rutvik S., Inoue, Taeko, Pautler, Robia G., Corry, David B., Tour, James M., Beeton, Christine

“…Autoimmune diseases mediated by a type of white blood cell—T lymphocytes—are currently treated using mainly broad-spectrum immunosuppressants that can lead to…”
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Inducible Lung Epithelial Resistance Requires Multisource Reactive Oxygen Species Generation To Protect against Viral Infections by Kirkpatrick, Carson T, Wang, Yongxing, Leiva Juarez, Miguel M, Shivshankar, Pooja, Pantaleón García, Jezreel, Plumer, Alexandria K, Kulkarni, Vikram V, Ware, Hayden H, Gulraiz, Fahad, Chavez Cavasos, Miguel A, Martinez Zayas, Gabriela, Wali, Shradha, Rice, Andrew P, Liu, Hongbing, Tour, James M, Sikkema, William K A, Cruz Solbes, Ana S, Youker, Keith A, Tuvim, Michael J, Dickey, Burton F, Evans, Scott E

“…Viral pneumonias cause profound worldwide morbidity, necessitating novel strategies to prevent and treat these potentially lethal infections. Stimulation of…”
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Nanoparticulate carbon black in cigarette smoke induces DNA cleavage and Th17-mediated emphysema by You, Ran, Lu, Wen, Shan, Ming, Berlin, Jacob M, Samuel, Errol Lg, Marcano, Daniela C, Sun, Zhengzong, Sikkema, William Ka, Yuan, Xiaoyi, Song, Lizhen, Hendrix, Amanda Y, Tour, James M, Corry, David B, Kheradmand, Farrah

“…Chronic inhalation of cigarette smoke is the major cause of sterile inflammation and pulmonary emphysema. The effect of carbon black (CB), a universal…”
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Effect of Graphene Nanoribbons (TexasPEG) on locomotor function recovery in a rat model of lumbar spinal cord transection by Kim, C-Yoon, Sikkema, William, Kim, Jin, Kim, Jeong, Walter, James, Dieter, Raymond, Chung, Hyung-Min, Mana, Andrea, Tour, James, Canavero, Sergio

“…A sharply transected spinal cord has been shown to be fused under the accelerating influence of membrane fusogens such as polyethylene glycol (PEG) (GEMINI…”
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Carbon nanoparticles and oxidative stress: could an injection stop brain damage in minutes? by Nilewski, Lizanne G, Sikkema, William KA, Kent, Thomas A, Tour, James M

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Physical and electrical characterization of TexasPEG: An electrically conductive neuronal scaffold by Sikkema, William, Metzger, Andrew, Wang, Tuo, Tour, James

“…Background: Graphene and its derivatives have been shown to be biocompatible and electrically active materials upon which neurons readily grow. The fusogen…”
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Spinal cord fusion with PEG-GNRs (TexasPEG): Neurophysiological recovery in 24 hours in rats by Kim, C-Yoon, Sikkema, WilliamK. A., Hwang, In-Kyu, Oh, Hanseul, Kim, UnJeng, Lee, BaeHwan, Tour, JamesM

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The microRNA miR-22 inhibits the histone deacetylase HDAC4 to promote TH17 cell–dependent emphysema by Lu, Wen, You, Ran, Yuan, Xiaoyi, Yang, Tianshu, Samuel, Errol L G, Marcano, Daniela C, Sikkema, William K A, Tour, James M, Rodriguez, Antony, Kheradmand, Farrah, Corry, David B

“…Smoking can lead to emphysema. Corry and colleagues show that smoke and carbon black particles induce the microRNA miR-22 as a mediator that suppresses…”
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The microRNA miR-22 inhibits the histone deacetylase HDAC4 to promote T(H)17 cell-dependent emphysema by Lu, Wen, You, Ran, Yuan, Xiaoyi, Yang, Tianshu, Samuel, Errol L G, Marcano, Daniela C, Sikkema, William K A, Tour, James M, Rodriguez, Antony, Kheradmand, Farrah, Corry, David B

“…Smoking-related emphysema is a chronic inflammatory disease driven by the T(H)17 subset of helper T cells through molecular mechanisms that remain obscure…”
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