Search Results - "Sikha, Thoduvayil"

Comparative proteome analysis reveals pathogen specific outer membrane proteins of Leptospira by Dhandapani, Gunasekaran, Sikha, Thoduvayil, Rana, Aarti, Brahma, Rahul, Akhter, Yusuf, Gopalakrishnan Madanan, Madathiparambil

“…Proteomes of pathogenic Leptospira interrogans and L. borgpetersenii and the saprophytic L. biflexa were filtered through computational tools to identify Outer…”
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Extracellular Proteome Analysis Shows the Abundance of Histidine Kinase Sensor Protein, DNA Helicase, Putative Lipoprotein Containing Peptidase M75 Domain and Peptidase C39 Domain Protein in Leptospira interrogans Grown in EMJH Medium by Sarma, Abhijit, Gunasekaran, Dhandapani, Rex, Devasahayam Arokia Balaya, Sikha, Thoduvayil, Phukan, Homen, Kiran, Kumar Mangalaparthi, Pinto, Sneha M., Prasad, Thottethodi Subrahmanya Keshava, Madanan, Madathiparambil G.

“…Leptospirosis is a re-emerging form of zoonosis that is caused by the spirochete pathogen Leptospira. Extracellular proteins play critical roles in the…”
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Photosensitive Nanoprobes for Rapid High Purity Isolation and Size‐Specific Enrichment of Synthetic and Extracellular Vesicle Subpopulations (Adv. Funct. Mater. 34/2024) by Weerakkody, Jonathan S., Tseng, Tiffany, Topper, Mackenzie, Thoduvayil, Sikha, Radhakrishnan, Abhijith, Pincet, Frederic, Kyriakides, Themis R., Gunasekara, Roshan W., Ramakrishnan, Sathish

“…Photosensitive Nanoprobes In article number 2400390, Roshan W. Gunasekara, Sathish Ramakrishnan, and co‐workers develop photosensitive lipid nanoprobes to…”
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Photosensitive Nanoprobes for Rapid High Purity Isolation and Size‐Specific Enrichment of Synthetic and Extracellular Vesicle Subpopulations by Weerakkody, Jonathan S., Tseng, Tiffany, Topper, Mackenzie, Thoduvayil, Sikha, Radhakrishnan, Abhijith, Pincet, Frederic, Kyriakides, Themis R., Gunasekara, Roshan W., Ramakrishnan, Sathish

“…The biggest challenge in current isolation methods for lipid bilayer‐encapsulated vesicles, such as exosomes, secretory, and synthetic vesicles, lies in the…”
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Photosensitive Nanoprobes for Rapid Isolation and Size-Specific Enrichment of Synthetic and Extracellular Vesicle Subpopulations by Weerakkody, Jonathan S, Tseng, Tiffany, Topper, Mackenzie, Thoduvayil, Sikha, Radhakrishnan, Abhijith, Pincet, Frederic, Kyriakides, Themis R, Gunasekara, Roshan W, Ramakrishnan, Sathish

“…The biggest challenge in current isolation methods for lipid bilayer-encapsulated vesicles, such as exosomes, secretory, and synthetic vesicles, lies in the…”
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Rapid Quantification of First and Second Phase Insulin Secretion Dynamics using an In vitro Platform for Improving Insulin Therapy by Thoduvayil, Sikha, Weerakkody, Jonathan S., Sundaram, Ramalingam Venkat Kalyana, Topper, Mackenzie, Bera, Manindra, Coleman, Jeff, Li, Xia, Mariappan, Malaiyalam, Ramakrishnan, Sathish

“…•Quantitative assay for understanding the dynamics of insulin secretion in the 1st and 2nd phases.•Facilitates the discovery of cellular and signaling pathways…”
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Triton X‐114 Fractionated Subcellular Proteome of Leptospira interrogans Shows Selective Enrichment of Pathogenic and Outer Membrane Proteins in the Detergent Fraction by Thoduvayil, Sikha, Dhandapani, Gunasekaran, Brahma, Rahul, Devasahayam Arokia Balaya, Rex, Mangalaparthi, Kiran K., Patel, Krishna, Kumar, Manish, Tennyson, Jebasingh, Satheeshkumar, P. K., Kulkarni, Mahesh J., Pinto, Sneha M., Prasad, T. S. Keshava, Madanan, Madathiparambil G.

“…The Triton X‐114‐based solubilization and temperature‐dependent phase separation of proteins is used for subcellular fractionation where, aqueous, detergent,…”
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Proteomic approach and expression analysis revealed the differential expression of predicted leptospiral proteases capable of ECM degradation by Dhandapani, Gunasekaran, Sikha, Thoduvayil, Pinto, Sneha M., Kiran Kumar, M., Patel, Krishna, Kumar, Manish, Kumar, Vikram, Tennyson, Jebasingh, Satheeshkumar, P.K., Gowda, Harsha, Keshava Prasad, T.S., Madanan, M.G.

“…Leptospira, the causative agent of leptospirosis is known to have many proteases with potential to degrade extracellular matrix. However, a multipronged…”
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