Search Results - "Sikes, James D."

Western Diet Modifies Platelet Activation Profiles in Male Mice by Corken, Adam, Wahl, Elizabeth C, Sikes, James D, Thakali, Keshari M

“…The correlation between obesity and cardiovascular disease has long been understood, yet scant investigations endeavored to determine the impact of an…”
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Significant role of IL-1 signaling, but limited role of inflammasome activation, in oviduct pathology during Chlamydia muridarum genital infection by Nagarajan, Uma M, Sikes, James D, Yeruva, Laxmi, Prantner, Daniel

“…IL-1β has been implicated in the development of oviduct pathology during Chlamydia muridarum genital infection in the mouse model. The goal of this study was…”
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Impact of maternal high‐fat diet on offspring gut microbiota during short‐term high‐fat diet exposure in mice by Paz, Henry A., Buddha, Lasya, Zhong, Ying, Sikes, James D., Wankhade, Umesh D.

“…Alterations in the gut microbiome have been linked to obesity, with maternal high‐fat diet (HF) playing a role in shaping offspring microbiome composition…”
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Evaluation of a Plant-Based Infant Formula Containing Almonds and Buckwheat on Gut Microbiota Composition, Intestine Morphology, Metabolic and Immune Markers in a Neonatal Piglet Model by Gurung, Manoj, Rosa, Fernanda, Yelvington, Brooke, Terry, Nathan, Read, Quentin D, Piccolo, Brian D, Moody, Becky, Tripp, Patricia, Pittman, 3rd, Hoy E, Fay, Bobby L, Ross, Talyor J, Sikes, James D, Flowers, Jessica B, Fox, Renee, LeRoith, Tanya, Talatala, Rachelanne, Bar-Yoseph, Fabiana, Yeruva, Laxmi

“…A controlled-neonatal piglet trial was conducted to evaluate the impact of a plant-based infant formula containing buckwheat and almonds as the main source of…”
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Evaluation of the Safety of a Plant-Based Infant Formula Containing Almonds and Buckwheat in a Neonatal Piglet Model by Rosa, Fernanda, Yelvington, Brooke, Terry, Nathan, Tripp, Patricia, Pittman, 3rd, Hoy E, Fay, Bobby L, Ross, Taylor J, Sikes, James D, Flowers, Jessica B, Bar-Yoseph, Fabiana, Yeruva, Laxmi

“…A randomized neonatal piglet trial was conducted to evaluate the safety and the effects of a plant-based formula containing almonds and buckwheat as the main…”
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Critical Role for Interleukin-1β (IL-1β) during Chlamydia muridarum Genital Infection and Bacterial Replication-Independent Secretion of IL-1β in Mouse Macrophages by Prantner, Daniel, Darville, Toni, Sikes, James D, Andrews, Charles W. Jr, Brade, Helmut, Rank, Roger G, Nagarajan, Uma M

“…Recent findings have implicated interleukin-1β (IL-1β) as an important mediator of the inflammatory response in the female genital tract during chlamydial…”
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Type I Interferon Signaling Exacerbates Chlamydia muridarum Genital Infection in a Murine Model by Nagarajan, Uma M, Prantner, Daniel, Sikes, James D, Andrews, Charles W. Jr, Goodwin, Anna M, Nagarajan, Shanmugam, Darville, Toni

“…Type I interferons (IFNs) induced during in vitro chlamydial infection exert bactericidal and immunomodulatory functions. To determine the precise role of type…”
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Interferon Regulatory Transcription Factor 3 Protects Mice from Uterine Horn Pathology during Chlamydia muridarum Genital Infection by PRANTNER, Daniel, SIKES, James D, HENNINGS, Leah, SAVENKA, Alena V, BASNAKIAN, Alexei G, NAGARAJAN, Uma M

“…Classifications Services IAI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
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A modest change in housing temperature alters whole body energy expenditure and adipocyte thermogenic capacity in mice by Sadler, Daniel G, Treas, Lillie, Sikes, James D, Porter, Craig

“…Typical vivarium temperatures (20-26°C) induce facultative thermogenesis in mice, a process attributable in part to uncoupling protein-1 (UCP1). The impact of…”
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Parental cardiorespiratory fitness influences early life energetics and metabolic health by Sadler, Daniel G, Treas, Lillie, Ross, Taylor, Sikes, James D, Britton, Steven L, Koch, Lauren G, Piccolo, Brian D, Børsheim, Elisabet, Porter, Craig

“…High cardiorespiratory fitness (CRF) is associated with a reduced risk of metabolic disease and is linked to superior mitochondrial respiratory function. This…”
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Early Local Cytokine Profiles in Strains of Mice with Different Outcomes from Chlamydial Genital Tract Infection by DARVILLE, Toni, ANDREWS, Charles W, SIKES, James D, FRALEY, Patrick L, RANK, Roger G

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Effects of rhinovirus 39 infection on airway hyperresponsiveness to carbachol in human airways precision cut lung slices by Kennedy, Joshua L., Koziol-White, Cynthia J., Jeffus, Susanne, Rettiganti, Mallikarjuna R., Fisher, Paige, Kurten, Megan, Eze, Anthony, House, Suzanne, Sikes, James D., Askew, Emily, Putt, Claire, Panettieri, Reynold A., Jones, Stacie M., Kurten, Richard C.

“…A subset of the PCLS was then infected with RV39, with uninfected PCLS providing controls. Because PCLS airways frequently exhibit basal tone (data not shown),…”
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Genital Chlamydia infection in hyperlipidemic mouse models exacerbates atherosclerosis by Nagarajan, Uma M., Sikes, James D., Burris, Ramona L., Jha, Rajneesh, Popovic, Branimir, Fraungruber, Pamelia, Hennings, Leah, Haggerty, Catherine L., Nagarajan, Shanmugam

“…Atherosclerosis is a chronic inflammatory disease, and recent studies have shown that infection at remote sites can contribute to the progression of…”
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Mouse Strain-Dependent Chemokine Regulation of the Genital Tract T Helper Cell Type 1 Immune Response by DARVILLE, Toni, ANDREWS, Charles W, SIKES, James D, FRALEY, Patrick L, BRASWELL, Leah, RANK, Roger G

“…Classifications Services IAI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
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IL-33 and IL-13 Receptors Are Upregulated in Precision Cut Lung Slices from Donors with Asthma during RV39 Infection by Waldron, Jamie L, Currey, Dorothy J, House, Suzanne E, Sikes, James D, Jones, Stacie M, Kurten, Richard, Kennedy, Joshua, MD

“…Expression was normalized to beta-actin and uninfected tissue from the same lung and the same time point…”
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IL-25 Causes Airway Hyper-Responsiveness of Human Precision Cut Lung Slices from Donors with Asthma by Heath, Jordan, MD, Kurten, Richard, PhD, House, Suzanne E, Sikes, James D, Kurten, Megan, Jones, Stacie M., MD, Kennedy, Josh L., MD

“…Comparisons were made for innate immune responses between cohorts…”
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Long-term Walnut Oral Immunotherapy Induces Clinically Relevant Treatment Responses in Tree Nut Allergic Children by Scurlock, Amy M., MD, Rettiganti, Mallik, PhD, Hiegel, Anne M., RN, CRC, Gibson, Erica D., RN, Beckwith, Sarah, BS, House, Suzanne E, Sikes, James D, Chervinskiy, Sheva K., DO, Pesek, Robbie, MD, Perry, Tamara T., MD, Kennedy, Joshua, MD, Chandler, Peggy, APRN, Christie, Lynn, MS, RD, LD, Luo, Chunqiao, MS, Burks, A. Wesley, MD, Jones, Stacie M

“…Methods Subjects (median age 9 years) with allergy to walnut and another tTN (pecan, cashew, hazelnut, pistachio) received open label WOIT after completing…”
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Pioglitazone Attenuates Peanut Induced Anaphylaxis in a Mouse Model of Peanut Allergy by Scurlock, Amy M., MD, Sikes, James D, Payne, Jennifer N, House, Suzanne E, Jones, Stacie M., MD

“…Rationale Peroxisome proliferator activated receptor gamma (PPARγ) agonists such as pioglitazone (PIO) have demonstrated multiple roles in inflammation and…”
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Oral Allergy Symptoms and Pollen Sensitization in Tree Nut Allergic Subjects Receiving Walnut Oral Immunotherapy (WOIT) by Sood, Amika, Scurlock, Amy M., MD, Rettiganti, Mallikarjuna R., PhD, Hiegel, Anne M., RN, CRC, Sikes, James D, House, Suzanne E, Payne, Jennifer N, Bettis, Jessica L, Beckwith, Sarah E, Perry, Tamara T., MD, Pesek, Robbie D., MD, Kennedy, Josh L., MD, Chandler, Peggy L., APN, Luo, Chunqiao, MS, Jones, Stacie M., MD

“…Conclusions Oral allergy symptoms and pollen sensitization are common in multi-tree nut allergic subjects participating in a WOIT trial and complicate clinical…”
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Desensitization to Walnut and Test Tree Nuts during a Double Blind, Placebo Controlled Walnut Oral Immunotherapy Trial by Scurlock, Amy M., MD, Rettiganti, Mallikarjuna R., PhD, Hiegel, Anne M., RN, CRC, Sood, Amika, Daniel, Caroline, Beckwith, Sarah E, Bettis, Jessica L, Sikes, James D, House, Suzanne E, Payne, Jennifer N, Pesek, Robbie D., MD, Perry, Tamara T., MD, Chandler, Peggy L., APN, Kennedy, Josh L., MD, Luo, Chunqiao, MS, Christie, Lynn, MS, RD, LD, Jones, Stacie M., MD

“…Methods Fourteen subjects (median age 9 years) with allergy to walnut and another test tree nut (pecan, cashew, hazelnut, pistachio) were randomized (2:1) to…”
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