Search Results - "Sikela, J.M"

DUF1220 domains, cognitive disease, and human brain evolution by Dumas, L, Sikela, J M

“…We have established that human genome sequences encoding a novel protein domain, DUF1220, show a dramatically elevated copy number in the human lineage (>200…”
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Single pass sequencing and physical and genetic mapping of human brain cDNAs by Khan, A.S, Wilcox, A.S, Polymeropoulos, M.H, Hopkins, J.A, Stevens, T.J, Robinson, M, Orpana, A.K, Sikela, J.M

“…We have performed single pass sequencing of 1,024 human brain cDNAs, over 900 of which seem to represent new human genes. Library prescreening with total brain…”
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The γ-aminobutyric acid receptor γ3 subunit gene (GABRG3) is tightly linked to the α5 subunit gene (GABRA5) on human chromosome 15q11–q13 and is transcribed in the same orientation by Greger, V., Knoll, J.H.M., Woolf, E., Glatt, K., Tyndale, R.F., Delorey, T.M., Olsen, R.W., Tobin, A.J., Sikela, J.M., Nakatsu, Y., Brilliant, M.H., Whiting, P.J., Lalande, M.

“…GABA A receptors are heterooligomeric ligand-gated ion channels that mediate the effect of the inhibitory neurotransmitter γ-aminobutyric acid. The GABA A…”
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A radiation hybrid map of 18 growth factor, growth factor receptor, hormone receptor, or neurotransmitter receptor genes on the distal region of the long arm of chromosome 5 by Warrington, J A, Bailey, S K, Armstrong, E, Aprelikova, O, Alitalo, K, Dolganov, G M, Wilcox, A S, Sikela, J M, Wolfe, S F, Lovett, M

“…The distal portion of the long arm of human chromosome 5 contains an impressive number of genes encoding growth factors, growth factor receptors, and…”
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Integration of Transcript and Genetic Maps of Chromosome 16 at Near-1-Mb Resolution: Demonstration of a “Hot Spot” for Recombination at 16p12 by CALLEN, D.F., LANE, S.A., KOZMAN, H., KREMMIDIOTIS, G., WHITMORE, S.A., LOWENSTEIN, M., DOGGETT, N.A., KENMOCHI, N., PAGE, D.C., MAGLOTT, D.R., NIERMAN, W.C., MURAKAWA, K., BERRY, R., SIKELA, J.M., HOULGATTE, R., AUFFRAY, C., SUTHERLAND, G.R.

“…A single mapping resource, a mouse/human somatic cell panel with average distance between breakpoints of 1.2 Mb and a potential resolution of 1 Mb, has been…”
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Comparison of Fluorescent Genotyping Methods by Johannes, Meriam, Geyer, D.D., Berry, R., Walter, N.A.R., Sikela, J.M., Bateman, J.B.

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Genetic mapping of the gene for Ca2+/calmodulin-dependent protein kinase IV (Camk-4) to mouse chromosome 18 by Sikela, J M, Adamson, M C, Wilson-Shaw, D, Kozak, C A

“…Southern blot analysis of Chinese hamster x mouse somatic cell hybrids was used to map the gene for a serine/threonine protein kinase expressed in brain and…”
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Cloning and expression of a mouse adenine phosphoribosyltransferase gene by Sikela, J M, Khan, S A, Feliciano, E, Trill, J, Tischfield, J A, Stambrook, P J

“…A functional mouse adenine phosphoribosyltransferase (APRT) gene was identified and cloned by screening a mouse sperm genomic DNA library in lambda Charon 4A…”
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