Search Results - "Sik Eum, Won"

PEP-1–ribosomal protein S3 protects dopaminergic neurons in an MPTP-induced Parkinson's disease mouse model by Hee Ahn, Eun, Won Kim, Dae, Jea Shin, Min, Nam Kim, Young, Ri Kim, Hye, Jung Woo, Su, Mi Kim, So, Kim, Duk-Soo, Kim, Joon, Park, Jinseu, Sik Eum, Won, Hwang, Hyun Sook, Choi, Soo Young

“…Parkinson's disease (PD) is a neurodegenerative disease characterized by a gradual loss of dopaminergic (DA) neurons in the substantia nigra (SN) of the brain…”
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In vivo protein transduction: biologically active intact pep-1-superoxide dismutase fusion protein efficiently protects against ischemic insult by Sik Eum, Won, Won Kim, Dae, Koo Hwang, In, Yoo, Ki-Yeon, Kang, Tae-Cheon, Ho Jang, Sang, Soon Choi, Hee, Hyun Choi, Soo, Hoon Kim, Young, Young Kim, So, Yil Kwon, Hyeok, Hoon Kang, Jung, Kwon, Oh-Shin, Cho, Sung-Woo, Soo Lee, Kil, Park, Jinseu, Ho Won, Moo, Young Choi, Soo

“…Reactive oxygen species (ROS) are implicated in reperfusion injury after transient focal cerebral ischemia. The antioxidant enzyme Cu,Zn-superoxide dismutase…”
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Suppression of 12-O-tetradecanoylphorbol-13-acetate (TPA)-induced skin inflammation in mice by transduced Tat-Annexin protein by Lee, S.H., Hallym University, Chuncheon, Republic of Korea, Kim, D.W., Hallym University, Chuncheon, Republic of Korea, Eom, S.A., Hallym University, Chuncheon, Republic of Korea, Jun, S.Y., Hallym University, Chuncheon, Republic of Korea, Park, M.Y., Hallym University, Chuncheon, Republic of Korea, Kim, D.S., Soonchunhyang University College of Medicine, Cheonan, Republic of Korea, Kwon, H.J., Hallym University College of Medicine, Chuncheon, Republic of Korea, Kwon, H.Y., Hallym University College of Medicine, Chuncheon, Republic of Korea, Han, K.H., Hallym University, Chuncheon, Republic of Korea, Park, J.S., Hallym University, Chuncheon, Republic of Korea, Hwang, H.S., Hallym University, Chuncheon, Republic of Korea, Eum, W.S., Hallym University, Chuncheon, Republic of Korea, Choi, S.Y., Hallym University, Chuncheon, Republic of Korea

“…We examined that the protective effects of ANX1 on 12-O-tetradecanoylphorbol-13-acetate (TPA)-induced skin inflammation in animal models using a Tat-ANX1…”
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Copper chaperone for Cu,Zn-SOD supplement potentiates the Cu,Zn-SOD function of neuroprotective effects against ischemic neuronal damage in the gerbil hippocampus by Hwang, In Koo, Eum, Won Sik, Yoo, Ki-Yeon, Cho, Jun Hwi, Kim, Dae Won, Choi, Soo Hyun, Kang, Tae-Cheon, Kwon, Oh-Shin, Kang, Jung Hoon, Choi, Soo Young, Won, Moo Ho

“…In the present study, we investigated the chronological alterations in SOD1 and its copper chaperone (chaperone for superoxide dismutase, CCS)…”
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Tat-CIAPIN1 Prevents Pancreatic β-Cell Death in hIAPP-Induced RINm5F Cells and T2DM Animal Model by Yeo, Hyeon Ji, Shin, Min Jea, Yoo, Ki-Yeon, Jung, Bo Hyun, Eum, Won Sik, Choi, Soo Young

“…It is well known that the cytokine-induced apoptosis inhibitor 1 (CIAPIN1) protein plays an important role in biological progresses as an anti-apoptotic…”
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Protective Effects of PEP-1-GSTA2 Protein in Hippocampal Neuronal Cell Damage Induced by Oxidative Stress by Choi, Yeon Joo, Shin, Min Jea, Youn, Gi Soo, Park, Jung Hwan, Yeo, Hyeon Ji, Yeo, Eun Ji, Kwon, Hyun Jung, Lee, Lee Re, Kim, Na Yeon, Kwon, Su Yeon, Jung, Hyo Young, Cho, Yong-Jun, Kim, Dae Won, Park, Jinseu, Han, Kyu Hyung, Lee, Keun Wook, Park, Jong Kook, Lee, Chan Hee, Eum, Won Sik, Choi, Soo Young

“…Glutathione S-transferase alpha 2 (GSTA2), a member of the glutathione S-transferase family, plays the role of cellular detoxification against oxidative…”
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PEP-1-GLRX1 Reduces Dopaminergic Neuronal Cell Loss by Modulating MAPK and Apoptosis Signaling in Parkinson’s Disease by Choi, Yeon Joo, Kim, Dae Won, Shin, Min Jea, Yeo, Hyeon Ji, Yeo, Eun Ji, Lee, Lee Re, Song, Yejin, Kim, Duk-Soo, Han, Kyu Hyung, Park, Jinseu, Lee, Keun Wook, Park, Jong Kook, Eum, Won Sik, Choi, Soo Young

“…Parkinson’s disease (PD) is characterized mainly by the loss of dopaminergic neurons in the substantia nigra (SN) mediated via oxidative stress. Although…”
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Tat-Biliverdin Reductase A Exerts a Protective Role in Oxidative Stress-Induced Hippocampal Neuronal Cell Damage by Regulating the Apoptosis and MAPK Signaling by Kim, Sang Jin, Shin, Min Jea, Kim, Dae Won, Yeo, Hyeon Ji, Yeo, Eun Ji, Choi, Yeon Joo, Sohn, Eun Jeong, Han, Kyu Hyung, Park, Jinseu, Lee, Keun Wook, Park, Jong Kook, Cho, Yong-Jun, Kim, Duk-Soo, Eum, Won Sik, Choi, Soo Young

“…Reactive oxygen species (ROS) is major risk factor in neuronal diseases including ischemia. Although biliverdin reductase A (BLVRA) plays a pivotal role in…”
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Transduced PEP-1-AMPK inhibits the LPS-induced expression of COX-2 and iNOS in Raw264.7 cells by Shin, M.J., Hallym University Medical Center, Chunchon, Republic of Korea, Lee, Y.P., Hallym University Medical Center, Chunchon, Republic of Korea, Kim, D.W., Hallym University Medical Center, Chunchon, Republic of Korea, An, J.J., Hallym University Medical Center, Chunchon, Republic of Korea, Jang, S.H., Hallym University Medical Center, Chunchon, Republic of Korea, Cho, S.M., Hallym University Medical Center, Chunchon, Republic of Korea, Sheen, S.H., Hallym University Medical Center, Chunchon, Republic of Korea, Lee, H.R., Hallym University Medical Center, Chunchon, Republic of Korea, Kweon, H.Y., National Academy of Agricultural Science, RDA, Suwon, Republic of Korea, Kang, S.W., National Academy of Agricultural Science, RDA, Suwon, Republic of Korea, Lee, K.G., National Academy of Agricultural Science, RDA, Suwon, Republic of Korea, Park, J.S., Hallym University Medical Center, Chunchon, Republic of Korea, Eum, W.S., Hallym University Medical Center, Chunchon, Republic of Korea, Cho, Y.J., Hallym University Medical Center, Chunchon, Republic of Korea, Choi, S.Y., Hallym University Medical Center, Chunchon, Republic of Korea

“…AMP-activated protein kinase (AMPK) is a heterotrimeric enzyme that plays a central role in cellular metabolic stress. Modulation of nitric oxide (NO) and…”
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Tat-indoleamine 2,3-dioxygenase 1 elicits neuroprotective effects on ischemic injury by Park, Jung Hwan, Kim, Dae Won, Shin, Min Jea, Park, Jinseu, Han, Kyu Hyung, Lee, Keun Wook, Park, Jong Kook, Choi, Yeon Joo, Yeo, Hyeon Ji, Yeo, Eun Ji, Sohn, Eun Jeong, Kim, Hyoung-Chun, Shin, EunJoo, Cho, Sung-Woo, Kim, Duk-Soo, Cho, Yong-Jun, Eum, Won Sik, Choi, Soo Young

“…It is well known that oxidative stress participates in neuronal cell death caused production of reactive oxygen species (ROS). The increased ROS is a major…”
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Tat‐biliverdin reductase A protects INS‐1 cells from human islet amyloid polypeptide‐induced cytotoxicity by alleviating oxidative stress and ER stress by Lee, Su Jin, Kang, Hyung Kyung, Eum, Won Sik, Park, Jinseu, Choi, Soo Young, Kwon, Hyeok Yil

“…Human islet amyloid polypeptide (hIAPP), a major constituent of islet amyloid deposits, induces pancreatic β‐cell apoptosis and eventually contributes to…”
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Differential effects and changes of ceruloplasmin in the hippocampal CA1 region between adult and aged gerbils after transient cerebral ischemia by Yoo, Ki-Yeon, Hwang, In Koo, Eum, Won Sik, Kim, Dae Won, Kwon, Young-Guen, Kang, Tae-Cheon, Choi, Soo Young, Kim, Yong-Sun, Won, Moo Ho

“…In this study, we examined the differential effects and changes of ceruloplasmin between adult and aged gerbil hippocampus after transient forebrain ischemia…”
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Protective Role of Transduced Tat-Thioredoxin1 (Trx1) against Oxidative Stress-Induced Neuronal Cell Death via ASK1-MAPK Signal Pathway by Yeo, Eun Ji, Eum, Won Sik, Yeo, Hyeon Ji, Choi, Yeon Joo, Sohn, Eun Jeong, Kwon, Hyun Jung, Kim, Dae Won, Kim, Duk-Soo, Cho, Sung-Woo, Park, Jinseu, Han, Kyu Hyung, Lee, Keun Wook, Park, Jong Kook, Shin, Min Jea, Choi, Soo Young

“…Oxidative stress plays a crucial role in the development of neuronal disorders including brain ischemic injury. Thioredoxin 1 (Trx1), a 12 kDa oxidoreductase,…”
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PEP-1-PIN1 Promotes Hippocampal Neuronal Cell Survival by Inhibiting Cellular ROS and MAPK Phosphorylation by Park, Jung Hwan, Shin, Min Jea, Youn, Gi Soo, Yeo, Hyeon Ji, Yeo, Eun Ji, Kwon, Hyun Jung, Lee, Lee Re, Kim, Na Yeon, Kwon, Su Yeon, Kim, Su Min, Cho, Yong-Jun, Lee, Sung Ho, Jung, Hyo Young, Kim, Dae Won, Eum, Won Sik, Choi, Soo Young

“…The peptidyl-prolyl isomerase (PIN1) plays a vital role in cellular processes, including intracellular signaling and apoptosis. While oxidative stress is…”
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PEP-1-PON1 protein regulates inflammatory response in raw 264.7 macrophages and ameliorates inflammation in a TPA-induced animal model by Kim, Mi Jin, Jeong, Hoon Jae, Kim, Dae Won, Sohn, Eun Jeong, Jo, Hyo Sang, Kim, Duk-Soo, Kim, Hyun Ah, Park, Eun Young, Park, Jong Hoon, Son, Ora, Han, Kyu Hyung, Park, Jinseu, Eum, Won Sik, Choi, Soo Young

“…Paraoxonase 1 (PON1) is an antioxidant enzyme which plays a central role in various diseases. However, the mechanism and function of PON1 protein in…”
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Transduced PEP-1-FK506BP Ameliorates Atopic Dermatitis in NC/Nga Mice by Kim, So Young, Sohn, Eun Jeong, Kim, Dae Won, Jeong, Hoon Jae, Kim, Mi Jin, Kang, Hye Won, Shin, Min Jea, Ahn, Eun Hee, Kwon, Soon Won, Kim, Young Nam, Kwon, Hyung Joo, Kim, Tae-Yoon, Lee, Kil Soo, Park, Jinseu, Eum, Won Sik, Choi, Soo Young

“…Immunophilin, FK506-binding protein 12 (FK506BP), is a receptor protein for the immunosuppressive drug FK506 by the FK506BP/FK506 complex. However, the precise…”
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Neuroprotective effect of PEP-1-peroxiredoxin2 on CA1 regions in the hippocampus against ischemic insult by Jeong, Hoon Jae, Yoo, Dae Young, Kim, Dae Won, Yeo, Hyeon Ji, Cho, Su Bin, Hyeon, Jiye, Park, Jung Hwan, Park, Jinseu, Eum, Won Sik, Hwang, Hyun Sook, Won, Moo-Ho, Hwang, In Koo, Choi, Soo Young

“…Oxidative stress is a leading cause of various diseases, including ischemia and inflammation. Peroxiredoxin2 (PRX2) is one of six mammalian isoenzymes (PRX1–6)…”
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Topical transduction of superoxide dismutase mediated by HIV-1 Tat protein transduction domain ameliorates 12-O-tetradecanoylphorbol-13-acetate (TPA)-induced inflammation in mice by Song, Ha Yong, Lee, Ji Ae, Ju, Sung Mi, Yoo, Ki-Yeon, Won, Moo Ho, Kwon, Hyung-Joo, Eum, Won Sik, Jang, Sang Ho, Choi, Soo Young, Park, Jinseu

“…A domain (RKKRRQRRR) derived from HIV-1 Tat is one of the most efficient protein transduction domains (PTD) for delivering macromolecules including proteins…”
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Protective effects of cell permeable Tat-PIM2 protein on oxidative stress induced dopaminergic neuronal cell death by Shin, Min Jea, Eum, Won Sik, Youn, Gi Soo, Park, Jung Hwan, Yeo, Hyeon Ji, Yeo, Eun Ji, Kwon, Hyun Jung, Sohn, Eun Jeong, Lee, Lee Re, Kim, Na Yeon, Kwon, Su Yeon, Kim, Su Min, Jung, Hyo Young, Kim, Duk-Soo, Cho, Sung-Woo, Kwon, Oh-Shin, Kim, Dae Won, Choi, Soo Young

“…Oxidative stress is considered as one of the main causes of Parkinson's disease (PD), however the exact etiology of PD is still unknown. Although it is known…”
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Transduced PEP-1-ribosomal protein S3 (rpS3) ameliorates 12-O-tetradecanoylphorbol-13-acetate-induced inflammation in mice by Ahn, Eun Hee, Kim, Dae Won, Kang, Hye Won, Shin, Min Jae, Won, Moo Ho, Kim, Joon, Kim, Dong Joon, Kwon, Oh-Shin, Kang, Tae-Cheon, Han, Kyu Hyung, Park, Jinseu, Eum, Won Sik, Choi, Soo Young

“…Abstract This study investigated the preventive effect of ribosomal protein S3 (rpS3) on 12-O-tetradecanoylphorbol-13-acetate (TPA)-induced ear edema in mice…”
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