Search Results - "Sijtsma, Jeroen"

Ageing of Plasmodium falciparum malaria sporozoites alters their motility, infectivity and reduces immune activation in vitro by van Schuijlenburg, Roos, Azargoshasb, Samaneh, de Korne, Clarize M, Sijtsma, Jeroen C, Bezemer, Sascha, van der Ham, Alwin J, Baalbergen, Els, Geurten, Fiona, de Bes-Roeleveld, Laura M, Chevalley-Maurel, Severine C, van Oosterom, Matthias N, van Leeuwen, Fijs W B, Franke-Fayard, Blandine, Roestenberg, Meta

“…Sporozoites (SPZ), the infective form of Plasmodium falciparum malaria, can be inoculated into the human host skin by Anopheline mosquitoes. These SPZ migrate…”
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Excretion patterns of Schistosoma mansoni antigens CCA and CAA by adult male and female worms, using a mouse model and ex vivo parasite cultures by Casacuberta-Partal, Miriam, van Lieshout, Lisette, van Diepen, Angela, Sijtsma, Jeroen C., Ozir-Fazalalikhan, Arifa, Koopman, Jan Pieter R., de Dood, Claudia J., Corstjens, Paul L.A.M., van Dam, Govert J., Hokke, Cornelis H., Roestenberg, Meta

“…Assays which enable the detection of schistosome gut-associated circulating anodic (CAA) and cathodic (CCA) antigen in serum or urine are increasingly used as…”
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Early symptom-associated inflammatory responses shift to type 2 responses in controlled human schistosome infection by Houlder, Emma L, Stam, Koen A, Koopman, Jan Pieter R, König, Marion H, Langenberg, Marijke C C, Hoogerwerf, Marie-Astrid, Niewold, Paula, Sonnet, Friederike, Janse, Jacqueline J, Partal, Miriam Casacuberta, Sijtsma, Jeroen C, de Bes-Roeleveld, Laura H M, Kruize, Yvonne C M, Yazdanbakhsh, Maria, Roestenberg, Meta

“…Schistosomiasis is an infection caused by contact with -contaminated water and affects more than 230 million people worldwide with varying morbidity. The roles…”
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Safety and infectivity of female cercariae in Schistosoma-naïve, healthy participants: a controlled human Schistosoma mansoni infection study by Koopman, Jan Pieter R., Houlder, Emma L., Janse, Jacqueline J., Casacuberta-Partal, Miriam, Lamers, Olivia A.C., Sijtsma, Jeroen C., de Dood, Claudia, Hilt, Stan T., Ozir-Fazalalikhan, Arifa, Kuiper, Vincent P., Roozen, Geert V.T., de Bes-Roeleveld, Laura M., Kruize, Yvonne C.M., Wammes, Linda J., Smits, Hermelijn H., van Lieshout, Lisette, van Dam, Govert J., van Amerongen-Westra, Inge M., Meij, Pauline, Corstjens, Paul L.A.M., Jochems, Simon P., van Diepen, Angela, Yazdanbakhsh, Maria, Hokke, Cornelis H., Roestenberg, Meta

“…BACKGROUNDA controlled human infection model for schistosomiasis (CHI-S) can speed up vaccine development and provides insight into early immune responses…”
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Protective efficacy of short-term infection with Necator americanus hookworm larvae in healthy volunteers in the Netherlands: a single-centre, placebo-controlled, randomised, controlled, phase 1 trial by Hoogerwerf, Marie-Astrid, Janse, Jacqueline J, Kuiper, Vincent P, van Schuijlenburg, Roos, Kruize, Yvonne Cm, Sijtsma, Jeroen C, Nosoh, Beckley A, Koopman, Jan-Pieter R, Verbeek-Menken, Petra H, Westra, Inge M, Meij, Pauline, Brienen, Eric At, Visser, Leo G, van Lieshout, Lisette, Jochems, Simon P, Yazdanbakhsh, Maria, Roestenberg, Meta

“…Vaccine development against hookworm is hampered by the absence of the development of protective immunity in populations repeatedly exposed to hookworm,…”
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Impact of Recombinant Adenovirus Serotype 35 Priming versus Boosting of a Plasmodium falciparum Protein: Characterization of T- and B-Cell Responses to Liver-Stage Antigen 1 by Rodríguez, Ariane, Goudsmit, Jaap, Companjen, Arjen, Mintardjo, Ratna, Gillissen, Gert, Tax, Dennis, Sijtsma, Jeroen, Weverling, Gerrit Jan, Holterman, Lennart, Lanar, David E, Havenga, Menzo J.E, Radošević, Katarina

“…Prime-boost vaccination regimens with heterologous antigen delivery systems have indicated that redirection of the immune response is feasible. We showed…”
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Causal chemoprophylactic activity of cabamiquine against Plasmodium falciparum in a controlled human malaria infection: a randomised, double-blind, placebo-controlled study in the Netherlands by van der Plas, Johan L, Kuiper, Vincent P, Bagchus, Wilhelmina M, Bödding, Matthias, Yalkinoglu, Özkan, Tappert, Aliona, Seitzinger, Andrea, Spangenberg, Thomas, Bezuidenhout, Deon, Wilkins, Justin, Oeuvray, Claude, Dhingra, Satish K, Thathy, Vandana, Fidock, David A, Smidt, Lisanne C A, Roozen, Geert V T, Koopman, Jan Pieter R, Lamers, Olivia A C, Sijtsma, Jeroen, van Schuijlenburg, Roos, Wessels, Els, Meij, Pauline, Kamerling, Ingrid M C, Roestenberg, Meta, Khandelwal, Akash

“…Cabamiquine is a novel antimalarial that inhibits Plasmodium falciparum translation elongation factor 2. We investigated the causal chemoprophylactic activity…”
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Hsp70 Expression and Induction as a Readout for Detection of Immune Modulatory Components in Food by Wieten, Lotte, van der Zee, Ruurd, Goedemans, Renske, Sijtsma, Jeroen, Serafini, Mauro, Lubsen, Nicolette H., van Eden, Willem, Broere, Femke

“…Stress proteins such as heat shock proteins (Hsps) are up-regulated in cells in response to various forms of stress, like thermal and oxidative stress and…”
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High-level expression from two independent expression cassettes in replication-incompetent adenovirus type 35 vector by Vogels, Ronald, Zuijdgeest, David, van Meerendonk, Michelle, Companjen, Arjen, Gillissen, Gert, Sijtsma, Jeroen, Melis, Irene, Holterman, Lennart, Radosevic, Katarina, Goudsmit, Jaap, Havenga, Menzo J. E

“…1 Crucell Holland BV, PO Box 2048, 2301 CA Leiden, The Netherlands 2 Center of Poverty-Related Communicable Diseases, Academic Medical Center, Amsterdam, The…”
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Increased immunogenicity of recombinant Ad35-based malaria vaccine through formulation with aluminium phosphate adjuvant by Ophorst, Olga J.A.E, Radošević, Katarina, Klap, Jaco M, Sijtsma, Jeroen, Gillissen, Gert, Mintardjo, Ratna, van Ooij, Mark J.M, Holterman, Lennart, Companjen, Arjen, Goudsmit, Jaap, Havenga, Menzo J.E

“…Abstract Previously, we have shown the potency of recombinant Adenovirus serotype 35 viral vaccines (rAd35) to induce strong immune response against the…”
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Expression and immunogenicity of thePlasmodium falciparumcircumsporozoite protein: The role of GPI signal sequence by Ophorst, Olga JAE, Radosevic, Katarina, Ouwehand, Krista, van Beem, Wouter, Mintardjo, Ratna, Sijtsma, Jeroen, Kaspers, Jorn, Companjen, Arjen, Holterman, Lennart, Goudsmit, Jaap, Havenga, Menzo JE

“…Previous studies have shown that the immunogenicity of rodent malaria parasite-derived circumsporozoite protein (CS) can be improved by deleting the…”
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Expression and immunogenicity of the Plasmodium falciparum circumsporozoite protein: The role of GPI signal sequence by Ophorst, Olga J.A.E, Radošević, Katarina, Ouwehand, Krista, van Beem, Wouter, Mintardjo, Ratna, Sijtsma, Jeroen, Kaspers, Jorn, Companjen, Arjen, Holterman, Lennart, Goudsmit, Jaap, Havenga, Menzo J.E

“…Abstract Previous studies have shown that the immunogenicity of rodent malaria parasite-derived circumsporozoite protein (CS) can be improved by deleting the…”
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Safety and infectivity of female cercariae in Schistosoma-naïve, healthy participants: a controlled human Schistosoma mansoni infection studyResearch in context by Jan Pieter R. Koopman, Emma L. Houlder, Jacqueline J. Janse, Miriam Casacuberta-Partal, Olivia A.C. Lamers, Jeroen C. Sijtsma, Claudia de Dood, Stan T. Hilt, Arifa Ozir-Fazalalikhan, Vincent P. Kuiper, Geert V.T. Roozen, Laura M. de Bes-Roeleveld, Yvonne C.M. Kruize, Linda J. Wammes, Hermelijn H. Smits, Lisette van Lieshout, Govert J. van Dam, Inge M. van Amerongen-Westra, Pauline Meij, Paul L.A.M. Corstjens, Simon P. Jochems, Angela van Diepen, Maria Yazdanbakhsh, Cornelis H. Hokke, Meta Roestenberg

“…Background: A controlled human infection model for schistosomiasis (CHI-S) can speed up vaccine development and provides insight into early immune responses…”
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