Search Results - "Sijbers, Anneke M"

Using predicate and provenance information from a knowledge graph for drug efficacy screening by Vlietstra, Wytze J, Vos, Rein, Sijbers, Anneke M, van Mulligen, Erik M, Kors, Jan A

“…Biomedical knowledge graphs have become important tools to computationally analyse the comprehensive body of biomedical knowledge. They represent knowledge as…”
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Gene Array Analysis of Bone Morphogenetic Protein Type I Receptor‐Induced Osteoblast Differentiation by Korchynskyi, Olexander, Dechering, Koen J, Sijbers, Anneke M, Olijve, Wiebe, Ten Dijke, Peter

“…The genomic response to BMP was investigated by ectopic expression of activated BMP type I receptors in C2C12 myoblast using cDNA microarrays. Novel BMP…”
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Microarray analysis on Runx2-deficient mouse embryos reveals novel Runx2 functions and target genes during intramembranous and endochondral bone formation by Vaes, Bart L.T., Ducy, Patricia, Sijbers, Anneke M., Hendriks, José M.A., van Someren, Eugene P., de Jong, Nanning G., van den Heuvel, Edwin R., Olijve, Wiebe, van Zoelen, Everardus J.J., Dechering, Koen J.

“…A major challenge in developmental biology is to correlate genome-wide gene expression modulations with developmental processes in vivo. In this study, we…”
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Xeroderma Pigmentosum Group F Caused by a Defect in a Structure-Specific DNA Repair Endonuclease by Sijbers, Anneke M, de Laat, Wouter L, Ariza, Rafael R, Biggerstaff, Maureen, Wei, Ying-Fei, Moggs, Jonathan G, Carter, Kenneth C, Shell, Brenda K, Evans, Elizabeth, de Jong, Mariska C, Rademakers, Suzanne, de Rooij, Johan, Jaspers, Nicolaas G.J, Hoeijmakers, Jan H.J, Wood, Richard D

“…Nucleotide excision repair, which is defective in xeroderma pigmentosum (XP), involves incision of a DNA strand on each side of a lesion. We isolated a human…”
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Modification of LDL with oxidized 1-palmitoyl-2-arachidonoyl- sn-glycero-3-phosphorylcholine (oxPAPC) results in a novel form of minimally modified LDL that modulates gene expression in macrophages by Groeneweg, Mathijs, Vergouwe, Monique N., Scheffer, Peter G., Vermue, Hendrikus P.A., Sollewijn Gelpke, Maarten D., Sijbers, Anneke M., Leitinger, Norbert, Hofker, Marten H., de Winther, Menno P.J.

“…Oxidized phospholipids (oxPL) have been found in atherosclerotic plaques and have been associated with the development of atherosclerosis. To investigate the…”
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Plant homologue of human excision repair gene ERCC1 points to conservation of DNA repair mechanisms by Xu, Huiling, Swoboda, Ines, Bhalla, Prem L., Sijbers, Anneke M., Zhao, Chongxin, Ong, Eng‐kok, Hoeijmakers, Jan H. J., Singh, Mohan B.

“…Summary Nucleotide excision repair (NER), a highly versatile DNA repair mechanism, is capable of removing various types of DNA damage including those induced…”
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Mapping of interaction domains between human repair proteins ERCC1 and XPF by de Laat, Wouter L., Sijbers, Anneke M., Odijk, Hanny, Jaspers, Nicolaas G. J., Hoeijmakers, Jan H. J.

“…ERCC1-XPF is a heterodimeric protein complex involved in nucleotide excision repair and recombinational processes. Like its homologous complex in Saccharomyces…”
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Rapid and non-invasive diagnosis of the presence of ruptured atherosclerotic lesions by Cleutjens, Kitty B.J.M., Faber, Birgit C.G., Rousch, Mat, Hackeng, Tillman M., Vink, Cees, Sijbers, Anneke M., Black, Darcey, Kitslaar, Peter J.E.H.M., Daemen, Mat J.A.P.

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Mutational Analysis of the Human Nucleotide Excision Repair Gene ERCC1 by Sijbers, Anneke M., van der Spek, Peter J., Odijk, Hanny, van den Berg, Joke, van Duin, Marcel, Westerveld, Andries, Jaspers, Nicolaas G. J., Bootsma, Dirk, Hoeijmakers, Jan H. J.

“…The human DNA repair protein ERCC1 resides in a complex together with the ERCC4, ERCC11 and XP-F correcting activities, thought to perform the 5′ strand…”
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Homozygous R788W Point Mutation in the XPF Gene of a Patient with Xeroderma Pigmentosum and Late-Onset Neurologic Disease by Sijbers, Anneke M., van Voorst Vader, Pieter C., Snoek, Jos W., Raams, Anja, Jaspers, Nicolaas G.J., Kleijer, Wim J.

“…The second Caucasian xeroderma pigmentosum patient (XP42RO) belonging to complementation group F (XP-F) is described. Mild ocular photophobia was present from…”
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Complete restoration of normal DNA repair characteristics in group F xeroderma pigmentosum cells by over-expression of transfected XPF cDNA by YAGI, T, MATSUMURA, Y, SATO, M, NISHIGORI, C, MORI, T, SIJBERS, A. M, TAKEBE, H

“…XP-F cDNA was cloned into a mammalian expression vector plasmid, and introduced into group F xeroderma pigmentosum (XP-F) cells. Several cell clones possessing…”
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