Search Results - "Siitari, Harri"
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Quantification of dynamic morphological drug responses in 3D organotypic cell cultures by automated image analysis
Published in PloS one (08-05-2014)“…Glandular epithelial cells differentiate into complex multicellular or acinar structures, when embedded in three-dimensional (3D) extracellular matrix. The…”
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A relational database to identify differentially expressed genes in the endometrium and endometriosis lesions
Published in Scientific data (28-08-2020)“…Endometriosis is a common inflammatory estrogen-dependent gynecological disorder, associated with pelvic pain and reduced fertility in women. Several aspects…”
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REG4 Is Highly Expressed in Mucinous Ovarian Cancer: A Potential Novel Serum Biomarker
Published in PloS one (16-03-2016)“…Preoperative diagnostics of ovarian neoplasms rely on ultrasound imaging and the serum biomarkers CA125 and HE4. However, these markers may be elevated in…”
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Specific Noncompetitive Immunoassay for HT‑2 Mycotoxin Detection
Published in Analytical chemistry (Washington) (16-02-2016)“…Here we demonstrate a novel homogeneous one-step immunoassay, utilizing a pair of recombinant antibody antigen-binding fragments (Fab), that is specific for…”
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Microsystems for drug development and diagnostics
Published in European journal of pharmaceutical sciences (01-06-2008)Get full text
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Disposable roll-to-roll hot embossed electrophoresis chip for detection of antibiotic resistance gene mecA in bacteria
Published in Lab on a chip (21-01-2012)“…We present a high-throughput roll-to-roll (R2R) manufacturing process for foil-based polymethyl methacrylate (PMMA) chips of excellent optical quality. These…”
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Ovarian Endometriosis Signatures Established through Discovery and Directed Mass Spectrometry Analysis
Published in Journal of proteome research (07-11-2014)“…New molecular information on potential therapeutic targets or tools for noninvasive diagnosis for endometriosis are important for patient care and treatment…”
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Quantification of Dynamic Morphological Drug Responses in 3D Organotypic Cell Cultures by Automated Image Analysis: e96426
Published in PloS one (01-05-2014)“…Glandular epithelial cells differentiate into complex multicellular or acinar structures, when embedded in three-dimensional (3D) extracellular matrix. The…”
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9
Time-resolved Fluorometric Assay for Detection of Autoantibodies to Glutamic Acid Decarboxylase (GAD65)
Published in Clinical chemistry (Baltimore, Md.) (01-06-2003)“…Type 1 diabetes mellitus results from destruction of the pancreatic insulin-producing beta cells by a chronic autoimmune process. Methods are needed for the…”
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Dual-label time-resolved fluoroimmunoassay for the simultaneous detection of adenovirus and rotavirus in faeces
Published in Journal of virological methods (01-05-1990)“…Dual-label time-resolved fluoroimmunoassay (TR-FIA) was used for the simultaneous detection of adenovirus and rotavirus in stool specimens. A one-incubation 1…”
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Europium as a label in time-resolved immunofluorometric assays
Published in Analytical biochemistry (01-03-1984)“…A nonisotopic immunoassay has been developed based on a sensitive detection of europium (III) in water solution using time-resolved fluorometry. The europium…”
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Preparation of europium-labelled DNA probes and their properties
Published in Nucleic acids research (11-03-1991)“…A chemical method for labelling DNA with a europium chelate is presented. First, primary aliphatic amino groups are introduced onto DNA in a transamination…”
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Simultaneous detection of two cystic fibrosis alleles using dual-label time-resolved fluorometry
Published in Molecular and cellular probes (01-12-1992)“…A simple dual-label hybridization test for normal and mutant cystic fibrosis (CF) alleles is described. The assay is based on time-resolved fluorometry (TRF),…”
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Europium-Labeled Oligonucleotide Hybridization Probes: Preparation and Properties
Published in Bioconjugate chemistry (01-05-1994)“…A chemical method for labeling of oligonucleotide probes with europium chelates is presented. A modified deoxycytidine phosphoramidite is used to introduce…”
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Detection of mutation delta F508 in the cystic fibrosis gene using allele-specific PCR primers and time-resolved fluorometry
Published in Genome research (1992)“…A method to detect the main cystic fibrosis (CF) mutation delta F508 from dried blood spots, whole blood, or saliva using the polymerase chain reaction (PCR)…”
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Detection of amplified HTLV-I/-II viral sequences using time-resolved fluorometry
Published in Analytical biochemistry (01-04-1992)“…Since its discovery, the polymerase chain reaction (PCR) has been used for different purposes in the field of DNA research. We tested the PCR for the diagnosis…”
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Detection of Philadelphia chromosome using PCR and europium-labeled DNA probes
Published in Clinical biochemistry (01-10-1994)“…More than 95% of the patients with chronic myelogenous leukemia (CML) carry translocations between protooncogene abl of chromosome 9 and bcr gene of chromosome…”
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Time-resolved fluorometry in the diagnosis of Leber hereditary optic neuroretinopathy
Published in Human mutation (1994)“…We have applied time-resolved fluorometry (TRF) to construct a DNA hybridization assay for the diagnosis of Leber hereditary optic neuroretinopathy (LHON). A…”
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Simultaneous quantification of two plant viruses by double-label time-resolved immunofluorometric assay
Published in Journal of virological methods (01-01-1989)“…For simultaneous and sensitive detection of two antigens in one sample, monoclonal antibody (MAb) to potato virus M (PVM) was labelled with a lanthanide Eu3+…”
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