Search Results - "Sigurdsson, E.M."

S.13.02 Immunotherapy in tauopathies by Sigurdsson, E.M

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High titers of mucosal and systemic anti-PrP antibodies abrogate oral prion infection in mucosal-vaccinated mice by Goñi, F, Prelli, F, Schreiber, F, Scholtzova, H, Chung, E, Kascsak, R, Brown, D.R, Sigurdsson, E.M, Chabalgoity, J.A, Wisniewski, T

“…Abstract Significant outbreaks of prion disease linked to oral exposure of the prion agent have occurred in animal and human populations. These disorders are…”
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Tau immunotherapies: Lessons learned, current status and future considerations by Sandusky-Beltran, L.A., Sigurdsson, E.M.

“…The majority of clinical trials targeting the tau protein in Alzheimer's disease and other tauopathies are tau immunotherapies. Because tau pathology…”
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Neuronally expressed anti-tau scFv prevents tauopathy-induced phenotypes in Drosophila models by Krishnaswamy, Senthilkumar, Huang, Huai-Wei, Marchal, Isabella S., Ryoo, Hyung Don, Sigurdsson, Einar M.

“…We have derived single-chain variable fragments (scFv) from tau antibody hybridomas and previously shown their promise as imaging diagnostic agents. Here, we…”
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Mucosal vaccination delays or prevents prion infection via an oral route by Goñi, F., Knudsen, E., Schreiber, F., Scholtzova, H., Pankiewicz, J., Carp, R., Meeker, H.C., Rubenstein, R., Brown, D.R., Sy, M.-S., Chabalgoity, J.A., Sigurdsson, E.M., Wisniewski, T.

“…In recent years major outbreaks of prion disease linked to oral exposure of the prion agent have occurred in animal and human populations. These disorders are…”
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P.5.b.003 Assessing the effects of memantine in APP/PS1 transgenic mice by behavioural studies and ex vivo imaging of amyloid plaques using gadolinium labelled amyloid β peptides and μMRI by Scholtzova, H., Wadghiri, Y.Z., Sigurdsson, E.M., Douadi, M., Li, Y., Quartermain, D., Banerjee, P.K., Wisniewski, T.

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P4-290: Immunization with Aβ derivatives in Microcebus murinus: A primate lemurian model of Alzheimer’s disease by Trouche, S., Asuni, A.A., Wisniewski, T., Frangione, B., Sigurdsson, E.M., Verdier, Jm, Mestre-Frances, N.

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Bilateral Injections of Amyloid-β 25-35 into the Amygdala of Young Fischer Rats: Behavioral, Neurochemical, and Time Dependent Histopathological Effects by Sigurdsson, E.M, Lee, J.M, Dong, X.-W, Hejna, M.J, Lorens, S.A

“…To examine the time course of the histopathological effects of bilateral injections of amyloid-β 25-35 (Aβ) and to determine if these effects are associated…”
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P1-3 Vaccination par des dérivés du peptide Aß chez un lémurien, le microcèbe by Trouche, S., Asuni, A.A., Rouland, S., Maurice, T., Knudsen, E., Wisniewski, T., Frangione, B., Verdier, J.M., Sigurdsson, E.M., Mestre-Frances, N.

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β-Amyloid 25–35 and/or quinolinic acid injections into the basal forebrain of young male Fischer-344 rats: Behavioral, neurochemical and histological effects by Sigurdsson, E.M., Hejna, M.J., Lee, J.M., Lorens, S.A.

“…β-Amyloid peptides have been shown to potentiate the neurotoxic effect of excitatory amino acids in vitro. In order to determine if this occurs in vivo, four…”
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