Search Results - "Sigurðsson, Asgeir"

Spread of SARS-CoV-2 in the Icelandic Population by Gudbjartsson, Daniel F, Helgason, Agnar, Jonsson, Hakon, Magnusson, Olafur T, Melsted, Pall, Norddahl, Gudmundur L, Saemundsdottir, Jona, Sigurdsson, Asgeir, Sulem, Patrick, Agustsdottir, Arna B, Eiriksdottir, Berglind, Fridriksdottir, Run, Gardarsdottir, Elisabet E, Georgsson, Gudmundur, Gretarsdottir, Olafia S, Gudmundsson, Kjartan R, Gunnarsdottir, Thora R, Gylfason, Arnaldur, Holm, Hilma, Jensson, Brynjar O, Jonasdottir, Aslaug, Jonsson, Frosti, Josefsdottir, Kamilla S, Kristjansson, Thordur, Magnusdottir, Droplaug N, le Roux, Louise, Sigmundsdottir, Gudrun, Sveinbjornsson, Gardar, Sveinsdottir, Kristin E, Sveinsdottir, Maney, Thorarensen, Emil A, Thorbjornsson, Bjarni, Löve, Arthur, Masson, Gisli, Jonsdottir, Ingileif, Möller, Alma D, Gudnason, Thorolfur, Kristinsson, Karl G, Thorsteinsdottir, Unnur, Stefansson, Kari

“…Despite timely implementation of testing for SARS-CoV-2 virus, a contact-tracing scheme, and social-distancing measures, infection has spread in Iceland…”
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Characterizing mutagenic effects of recombination through a sequence-level genetic map by Halldorsson, Bjarni V, Palsson, Gunnar, Stefansson, Olafur A, Jonsson, Hakon, Hardarson, Marteinn T, Eggertsson, Hannes P, Gunnarsson, Bjarni, Oddsson, Asmundur, Halldorsson, Gisli H, Zink, Florian, Gudjonsson, Sigurjon A, Frigge, Michael L, Thorleifsson, Gudmar, Sigurdsson, Asgeir, Stacey, Simon N, Sulem, Patrick, Masson, Gisli, Helgason, Agnar, Gudbjartsson, Daniel F, Thorsteinsdottir, Unnur, Stefansson, Kari

“…Genetic diversity arises from recombination and de novo mutation (DNM). Using a combination of microarray genotype and whole-genome sequence data on…”
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Rate of de novo mutations and the importance of father’s age to disease risk by Kong, Augustine, Frigge, Michael L., Masson, Gisli, Besenbacher, Soren, Sulem, Patrick, Magnusson, Gisli, Gudjonsson, Sigurjon A., Sigurdsson, Asgeir, Jonasdottir, Aslaug, Jonasdottir, Adalbjorg, Wong, Wendy S. W., Sigurdsson, Gunnar, Walters, G. Bragi, Steinberg, Stacy, Helgason, Hannes, Thorleifsson, Gudmar, Gudbjartsson, Daniel F., Helgason, Agnar, Magnusson, Olafur Th, Thorsteinsdottir, Unnur, Stefansson, Kari

“…Mutations generate sequence diversity and provide a substrate for selection. The rate of de novo mutations is therefore of major importance to evolution. Here…”
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FLT3 stop mutation increases FLT3 ligand level and risk of autoimmune thyroid disease by Saevarsdottir, Saedis, Olafsdottir, Thorunn A., Ivarsdottir, Erna V., Halldorsson, Gisli H., Gunnarsdottir, Kristbjorg, Sigurdsson, Asgeir, Johannesson, Ari, Sigurdsson, Jon K., Juliusdottir, Thorhildur, Lund, Sigrun H., Arnthorsson, Asgeir O., Styrmisdottir, Edda L., Gudmundsson, Julius, Grondal, Gerdur M., Steinsson, Kristjan, Alfredsson, Lars, Askling, Johan, Benediktsson, Rafn, Bjarnason, Ragnar, Geirsson, Arni J., Gudbjornsson, Bjorn, Gudjonsson, Hallgrimur, Hjaltason, Haukur, Hreidarsson, Astradur B., Klareskog, Lars, Kockum, Ingrid, Kristjansdottir, Helga, Love, Thorvardur J., Ludviksson, Bjorn R., Olsson, Tomas, Onundarson, Pall T., Orvar, Kjartan B., Padyukov, Leonid, Sigurgeirsson, Bardur, Tragante, Vinicius, Bjarnadottir, Kristbjorg, Rafnar, Thorunn, Masson, Gisli, Sulem, Patrick, Gudbjartsson, Daniel F., Melsted, Pall, Thorleifsson, Gudmar, Norddahl, Gudmundur L., Thorsteinsdottir, Unnur, Jonsdottir, Ingileif, Stefansson, Kari

“…Autoimmune thyroid disease is the most common autoimmune disease and is highly heritable 1 . Here, by using a genome-wide association study of 30,234 cases and…”
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Identification of a large set of rare complete human knockouts by Sulem, Patrick, Helgason, Hannes, Oddson, Asmundur, Stefansson, Hreinn, Gudjonsson, Sigurjon A, Zink, Florian, Hjartarson, Eirikur, Sigurdsson, Gunnar Th, Jonasdottir, Adalbjorg, Jonasdottir, Aslaug, Sigurdsson, Asgeir, Magnusson, Olafur Th, Kong, Augustine, Helgason, Agnar, Holm, Hilma, Thorsteinsdottir, Unnur, Masson, Gisli, Gudbjartsson, Daniel F, Stefansson, Kari

“…Patrick Sulem, Hannes Helgason and colleagues identify homozygous and compound heterozygous loss-of-function variants of minor allele frequency <2% in 7.7% of…”
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Fine-scale recombination rate differences between sexes, populations and individuals by Gudbjartsson, Daniel F, Gudjonsson, Sigurjon A, Kristinsson, Kari Th, Helgason, Agnar, Gylfason, Arnaldur, Sigurdsson, Asgeir, Masson, Gisli, Stefansson, Kari, Frigge, Michael L, Walters, G. Bragi, Thorsteinsdottir, Unnur, Thorleifsson, Gudmar, Kong, Augustine, Jonasdottir, Aslaug, Jonasdottir, Adalbjorg

“…Meiotic recombinations contribute to genetic diversity by yielding new combinations of alleles. Recently, high-resolution recombination maps were inferred from…”
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A homozygous loss-of-function mutation leading to CYBC1 deficiency causes chronic granulomatous disease by Arnadottir, Gudny A., Norddahl, Gudmundur L., Gudmundsdottir, Steinunn, Agustsdottir, Arna B., Sigurdsson, Snaevar, Jensson, Brynjar O., Bjarnadottir, Kristbjorg, Theodors, Fannar, Benonisdottir, Stefania, Ivarsdottir, Erna V., Oddsson, Asmundur, Kristjansson, Ragnar P., Sulem, Gerald, Alexandersson, Kristjan F., Juliusdottir, Thorhildur, Gudmundsson, Kjartan R., Saemundsdottir, Jona, Jonasdottir, Adalbjorg, Jonasdottir, Aslaug, Sigurdsson, Asgeir, Manzanillo, Paolo, Gudjonsson, Sigurjon A., Thorisson, Gudmundur A., Magnusson, Olafur Th, Masson, Gisli, Orvar, Kjartan B., Holm, Hilma, Bjornsson, Sigurdur, Arngrimsson, Reynir, Gudbjartsson, Daniel F., Thorsteinsdottir, Unnur, Jonsdottir, Ingileif, Haraldsson, Asgeir, Sulem, Patrick, Stefansson, Kari

“…Mutations in genes encoding subunits of the phagocyte NADPH oxidase complex are recognized to cause chronic granulomatous disease (CGD), a severe primary…”
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A rare IL33 loss-of-function mutation reduces blood eosinophil counts and protects from asthma by Smith, Dirk, Helgason, Hannes, Sulem, Patrick, Bjornsdottir, Unnur Steina, Lim, Ai Ching, Sveinbjornsson, Gardar, Hasegawa, Haruki, Brown, Michael, Ketchem, Randal R, Gavala, Monica, Garrett, Logan, Jonasdottir, Adalbjorg, Jonasdottir, Aslaug, Sigurdsson, Asgeir, Magnusson, Olafur T, Eyjolfsson, Gudmundur I, Olafsson, Isleifur, Onundarson, Pall Torfi, Sigurdardottir, Olof, Gislason, David, Gislason, Thorarinn, Ludviksson, Bjorn Runar, Ludviksdottir, Dora, Boezen, H Marike, Heinzmann, Andrea, Krueger, Marcus, Porsbjerg, Celeste, Ahluwalia, Tarunveer S, Waage, Johannes, Backer, Vibeke, Deichmann, Klaus A, Koppelman, Gerard H, Bønnelykke, Klaus, Bisgaard, Hans, Masson, Gisli, Thorsteinsdottir, Unnur, Gudbjartsson, Daniel F, Johnston, James A, Jonsdottir, Ingileif, Stefansson, Kari

“…IL-33 is a tissue-derived cytokine that induces and amplifies eosinophilic inflammation and has emerged as a promising new drug target for asthma and allergic…”
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Comprehensive population-wide analysis of Lynch syndrome in Iceland reveals founder mutations in MSH6 and PMS2 by Haraldsdottir, Sigurdis, Rafnar, Thorunn, Frankel, Wendy L., Einarsdottir, Sylvia, Sigurdsson, Asgeir, Hampel, Heather, Snaebjornsson, Petur, Masson, Gisli, Weng, Daniel, Arngrimsson, Reynir, Kehr, Birte, Yilmaz, Ahmet, Haraldsson, Stefan, Sulem, Patrick, Stefansson, Tryggvi, Shields, Peter G., Sigurdsson, Fridbjorn, Bekaii-Saab, Tanios, Moller, Pall H., Steinarsdottir, Margret, Alexiusdottir, Kristin, Hitchins, Megan, Pritchard, Colin C., de la Chapelle, Albert, Jonasson, Jon G., Goldberg, Richard M., Stefansson, Kari

“…Lynch syndrome, caused by germline mutations in the mismatch repair genes, is associated with increased cancer risk. Here using a large whole-genome sequencing…”
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Loss-of-function variants in ATM confer risk of gastric cancer by Helgason, Hannes, Rafnar, Thorunn, Olafsdottir, Halla S, Jonasson, Jon G, Sigurdsson, Asgeir, Stacey, Simon N, Jonasdottir, Adalbjorg, Tryggvadottir, Laufey, Alexiusdottir, Kristin, Haraldsson, Asgeir, le Roux, Louise, Gudmundsson, Julius, Johannsdottir, Hrefna, Oddsson, Asmundur, Gylfason, Arnaldur, Magnusson, Olafur T, Masson, Gisli, Jonsson, Thorvaldur, Skuladottir, Halla, Gudbjartsson, Daniel F, Thorsteinsdottir, Unnur, Sulem, Patrick, Stefansson, Kari

“…Hannes Helgason, Kari Stefansson and colleagues report an association study of gastric cancer susceptibility based on whole-genome sequencing in the Icelandic…”
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Mutations in BRIP1 confer high risk of ovarian cancer by Rafnar, Thorunn, Stefansson, Kari, Gudbjartsson, Daniel F, Sulem, Patrick, Jonasdottir, Aslaug, Sigurdsson, Asgeir, Jonasdottir, Adalbjorg, Besenbacher, Soren, Lundin, Pär, Stacey, Simon N, Gudmundsson, Julius, Magnusson, Olafur T, le Roux, Louise, Orlygsdottir, Gudbjorg, Helgadottir, Hafdis T, Johannsdottir, Hrefna, Gylfason, Arnaldur, Tryggvadottir, Laufey, Jonasson, Jon G, de Juan, Ana, Ortega, Eugenia, Ramon-Cajal, Jose M, García-Prats, Maria D, Mayordomo, Carlos, Panadero, Angeles, Rivera, Fernando, Aben, Katja K H, van Altena, Anne M, Massuger, Leon F A G, Aavikko, Mervi, Kujala, Paula M, Staff, Synnöve, Aaltonen, Lauri A, Olafsdottir, Kristrun, Bjornsson, Johannes, Kong, Augustine, Salvarsdottir, Anna, Saemundsson, Hafsteinn, Olafsson, Karl, Benediktsdottir, Kristrun R, Gulcher, Jeffrey, Masson, Gisli, Kiemeney, Lambertus A, Mayordomo, Jose I, Thorsteinsdottir, Unnur

“…Ovarian cancer causes more deaths than any other gynecologic malignancy in developed countries. Sixteen million sequence variants, identified through…”
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International Association of Dental Traumatology guidelines for the management of traumatic dental injuries: 2. Avulsion of permanent teeth by Andersson, Lars, Andreasen, Jens O., Day, Peter, Heithersay, Geoffrey, Trope, Martin, DiAngelis, Anthony J., Kenny, David J., Sigurdsson, Asgeir, Bourguignon, Cecilia, Flores, Marie Therese, Hicks, Morris Lamar, Lenzi, Antonio R., Malmgren, Barbro, Moule, Alex J., Tsukiboshi, Mitsuhiro

“…–  Avulsion of permanent teeth is one of the most serious dental injuries, and a prompt and correct emergency management is very important for the prognosis…”
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Common Variant on Chromosome 9p21 Affects the Risk of Myocardial Infarction by Helgadottir, Anna, Thorleifsson, Gudmar, Manolescu, Andrei, Gretarsdottir, Solveig, Blondal, Thorarinn, Jonasdottir, Aslaug, Jonasdottir, Adalbjorg, Sigurdsson, Asgeir, Baker, Adam, Palsson, Arnar, Masson, Gisli, Gudbjartsson, Daniel F, Magnusson, Kristinn P, Andersen, Karl, Levey, Allan I, Backman, Valgerdur M, Matthiasdottir, Sigurborg, Jonsdottir, Thorbjorg, Palsson, Stefan, Einarsdottir, Helga, Gunnarsdottir, Steinunn, Gylfason, Arnaldur, Vaccarino, Viola, Hooper, W. Craig, Reilly, Muredach P, Granger, Christopher B, Austin, Harland, Rader, Daniel J, Shah, Svati H, Quyyumi, Arshed A, Gulcher, Jeffrey R, Thorgeirsson, Gudmundur, Thorsteinsdottir, Unnur, Kong, Augustine, Stefansson, Kari

“…The global endemic of cardiovascular diseases calls for improved risk assessment and treatment. Here, we describe an association between myocardial infarction…”
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Ancient genomes from Iceland reveal the making of a human population by Ebenesersdóttir, S Sunna, Sandoval-Velasco, Marcela, Gunnarsdóttir, Ellen D, Jagadeesan, Anuradha, Guðmundsdóttir, Valdís B, Thordardóttir, Elísabet L, Einarsdóttir, Margrét S, Moore, Kristjan H S, Sigurðsson, Ásgeir, Magnúsdóttir, Droplaug N, Jónsson, Hákon, Snorradóttir, Steinunn, Hovig, Eivind, Møller, Pål, Kockum, Ingrid, Olsson, Tomas, Alfredsson, Lars, Hansen, Thomas F, Werge, Thomas, Cavalleri, Gianpiero L, Gilbert, Edmund, Lalueza-Fox, Carles, Walser, 3rd, Joe W, Kristjánsdóttir, Steinunn, Gopalakrishnan, Shyam, Árnadóttir, Lilja, Magnússon, Ólafur Þ, Gilbert, M Thomas P, Stefánsson, Kári, Helgason, Agnar

“…Opportunities to directly study the founding of a human population and its subsequent evolutionary history are rare. Using genome sequence data from 27 ancient…”
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The Y-chromosome point mutation rate in humans by Helgason, Agnar, Einarsson, Axel W, Guðmundsdóttir, Valdís B, Sigurðsson, Ásgeir, Gunnarsdóttir, Ellen D, Jagadeesan, Anuradha, Ebenesersdóttir, S Sunna, Kong, Augustine, Stefánsson, Kári

“…Agnar Helgason and colleagues report the point mutation rate for the male-specific euchromatic sequence of the Y chromosome based on 753 Icelandic males. They…”
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International Association of Dental Traumatology guidelines for the management of traumatic dental injuries: 1. Fractures and luxations of permanent teeth by DiAngelis, Anthony J., Andreasen, Jens O., Ebeleseder, Kurt A., Kenny, David J., Trope, Martin, Sigurdsson, Asgeir, Andersson, Lars, Bourguignon, Cecilia, Flores, Marie Therese, Hicks, Morris Lamar, Lenzi, Antonio R., Malmgren, Barbro, Moule, Alex J., Pohl, Yango, Tsukiboshi, Mitsuhiro

“…–  Traumatic dental injuries (TDIs) of permanent teeth occur frequently in children and young adults. Crown fractures and luxations are the most commonly…”
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Large-Scale Screening for Monogenic and Clinically Defined Familial Hypercholesterolemia in Iceland by Björnsson, Eythór, Thorgeirsson, Guðmundur, Helgadóttir, Anna, Thorleifsson, Guðmar, Sveinbjörnsson, Garðar, Kristmundsdóttir, Snaedís, Jónsson, Hákon, Jónasdóttir, Aðalbjörg, Jónasdóttir, Áslaug, Sigurðsson, Ásgeir, Guðnason, Thórarinn, Ólafsson, Ísleifur, Sigurðsson, Emil L., Sigurðardóttir, Ólöf, Viðarsson, Brynjar, Baldvinsson, Magnús, Bjarnason, Ragnar, Danielsen, Ragnar, Matthíasson, Stefán E., Thórarinsson, Björn L., Grétarsdóttir, Sólveig, Steinthórsdóttir, Valgerður, Halldórsson, Bjarni V., Andersen, Karl, Arnar, Davíð O., Jónsdóttir, Ingileif, Guðbjartsson, Daníel F., Hólm, Hilma, Thorsteinsdóttir, Unnur, Sulem, Patrick, Stefánsson, Kári

“…Objective: Familial hypercholesterolemia (FH) is traditionally defined as a monogenic disease characterized by severely elevated LDL-C (low-density lipoprotein…”
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Regenerative Endodontic Procedures for Traumatized Teeth after Horizontal Root Fracture, Avulsion, and Perforating Root Resorption by Saoud, Tarek Mohamed A., BDS, MSc, PhD, Mistry, Sonali, MDSc, Kahler, Bill, DClinDent, PhD, Sigurdsson, Asgeir, DDS, MS, Lin, Louis M., BDS, DMD, PhD

“…Abstract Introduction Traumatic injury to the teeth can cause horizontal root fractures and inflammatory root resorptions (external and internal)…”
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Treatment of Mature Permanent Teeth with Necrotic Pulps and Apical Periodontitis Using Regenerative Endodontic Procedures: A Case Series by Saoud, Tarek Mohamed, BDS, MSC, PhD, Martin, Gabriela, DDS, PhD, Chen, Yea-Huey M., DDS, MS, Chen, Kuang-Liang, DDS, Chen, Chao-An, DDS, Songtrakul, Kamolthip, DDS, MS, Malek, Matthew, DDS, Sigurdsson, Asgeir, DDS, MS, Lin, Louis M., BDS, DMD, PhD

“…Abstract Introduction Regenerative endodontic procedures (REPs) are usually used to treat human immature permanent teeth with necrotic pulps and/or apical…”
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Sequence variants in ARHGAP15, COLQ and FAM155A associate with diverticular disease and diverticulitis by Sigurdsson, Snaevar, Alexandersson, Kristjan F., Sulem, Patrick, Feenstra, Bjarke, Gudmundsdottir, Steinunn, Halldorsson, Gisli H., Olafsson, Sigurgeir, Sigurdsson, Asgeir, Rafnar, Thorunn, Thorgeirsson, Thorgeir, Sørensen, Erik, Nordholm-Carstensen, Andreas, Burcharth, Jakob, Andersen, Jens, Jørgensen, Henrik Stig, Possfelt-Møller, Emma, Ullum, Henrik, Thorleifsson, Gudmar, Masson, Gisli, Thorsteinsdottir, Unnur, Melbye, Mads, Gudbjartsson, Daniel F., Stefansson, Tryggvi, Jonsdottir, Ingileif, Stefansson, Kari

“…Diverticular disease is characterized by pouches (that is, diverticulae) due to weakness in the bowel wall, which can become infected and inflamed causing…”
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