Search Results - "Signorini, Stefano"

The Seveso accident: A look at 40 years of health research and beyond by Eskenazi, Brenda, Warner, Marcella, Brambilla, Paolo, Signorini, Stefano, Ames, Jennifer, Mocarelli, Paolo

“…A 1976 chemical factory explosion near Seveso, Italy exposed residents to high levels of 2,3,7,8-tetracholorodibenzo-p-dioxin (TCDD or dioxin). Dioxin is a…”
Get full text

Lipoprotein(a) and the risk of cardiovascular disease in the European population: results from the BiomarCaRE consortium by Waldeyer, Christoph, Makarova, Nataliya, Zeller, Tanja, Schnabel, Renate B, Brunner, Fabian J, Jørgensen, Torben, Linneberg, Allan, Niiranen, Teemu, Salomaa, Veikko, Jousilahti, Pekka, Yarnell, John, Ferrario, Marco M, Veronesi, Giovanni, Brambilla, Paolo, Signorini, Stefano G, Iacoviello, Licia, Costanzo, Simona, Giampaoli, Simona, Palmieri, Luigi, Meisinger, Christa, Thorand, Barbara, Kee, Frank, Koenig, Wolfgang, Ojeda, Francisco, Kontto, Jukka, Landmesser, Ulf, Kuulasmaa, Kari, Blankenberg, Stefan

“…As promising compounds to lower Lipoprotein(a) (Lp(a)) are emerging, the need for a precise characterization and comparability of the Lp(a)-associated…”
Get full text

In utero dioxin exposure and cardiometabolic risk in the Seveso Second Generation Study by Warner, Marcella, Rauch, Stephen, Ames, Jennifer, Mocarelli, Paolo, Brambilla, Paolo, Signorini, Stefano, Eskenazi, Brenda

“…Background/objectives In utero exposure to endocrine-disrupting compounds such as 2,3,7,8-tetrachlorodibenzo- p -dioxin (TCDD) may alter risk of obesity and…”
Get full text

Prenatal dioxin exposure and thyroid hormone levels in the Seveso second generation study by Warner, Marcella, Rauch, Stephen, Ames, Jennifer, Mocarelli, Paolo, Brambilla, Paolo, Signorini, Stefano, Eskenazi, Brenda

“…In animal studies, perinatal exposure to 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) alters thyroid homoeostasis and thyroid hormone concentrations;…”
Get full text

Impact of a Mediterranean Dietary Pattern and Its Components on Cardiovascular Risk Factors, Glucose Control, and Body Weight in People with Type 2 Diabetes: A Real-Life Study by Vitale, Marilena, Masulli, Maria, Calabrese, Ilaria, Rivellese, Angela Albarosa, Bonora, Enzo, Signorini, Stefano, Perriello, Gabriele, Squatrito, Sebastiano, Buzzetti, Raffaella, Sartore, Giovanni, Babini, Anna Carla, Gregori, Giovanna, Giordano, Carla, Clemente, Gennaro, Grioni, Sara, Dolce, Pasquale, Riccardi, Gabriele, Vaccaro, Olga

“…This study evaluates the relation of a Mediterranean dietary pattern and its individual components with the cardiovascular risk factors profile, plasma glucose…”
Get full text

Prenatal dioxin exposure and neuropsychological functioning in the Seveso Second Generation Health Study by Ames, Jennifer, Warner, Marcella, Siracusa, Claudia, Signorini, Stefano, Brambilla, Paolo, Mocarelli, Paolo, Eskenazi, Brenda

“…Prenatal 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) exposure has been shown to alter sexual differentiation of the brain in animal models, impacting pubertal…”
Get full text

Prenatal dioxin exposure and glucose metabolism in the Seveso Second Generation study by Warner, Marcella, Rauch, Stephen, Brambilla, Paolo, Signorini, Stefano, Mocarelli, Paolo, Eskenazi, Brenda

“…•The Seveso Second Generation study is a cohort of children born to TCDD-exposed women.•We examined associations of in utero TCDD exposure with glucose…”
Get full text

Genome-wide association study of blood pressure extremes identifies variant near UMOD associated with hypertension by Padmanabhan, Sandosh, Melander, Olle, Johnson, Toby, Di Blasio, Anna Maria, Lee, Wai K, Gentilini, Davide, Hastie, Claire E, Menni, Cristina, Monti, Maria Cristina, Delles, Christian, Laing, Stewart, Corso, Barbara, Navis, Gerjan, Kwakernaak, Arjan J, van der Harst, Pim, Bochud, Murielle, Maillard, Marc, Burnier, Michel, Hedner, Thomas, Kjeldsen, Sverre, Wahlstrand, Björn, Sjögren, Marketa, Fava, Cristiano, Montagnana, Martina, Danese, Elisa, Torffvit, Ole, Hedblad, Bo, Snieder, Harold, Connell, John M C, Brown, Morris, Samani, Nilesh J, Farrall, Martin, Cesana, Giancarlo, Mancia, Giuseppe, Signorini, Stefano, Grassi, Guido, Eyheramendy, Susana, Wichmann, H Erich, Laan, Maris, Strachan, David P, Sever, Peter, Shields, Denis Colm, Stanton, Alice, Vollenweider, Peter, Teumer, Alexander, Völzke, Henry, Rettig, Rainer, Newton-Cheh, Christopher, Arora, Pankaj, Zhang, Feng, Soranzo, Nicole, Spector, Timothy D, Lucas, Gavin, Kathiresan, Sekar, Siscovick, David S, Luan, Jian'an, Loos, Ruth J F, Wareham, Nicholas J, Penninx, Brenda W, Nolte, Ilja M, McBride, Martin, Miller, William H, Nicklin, Stuart A, Baker, Andrew H, Graham, Delyth, McDonald, Robert A, Pell, Jill P, Sattar, Naveed, Welsh, Paul, Munroe, Patricia, Caulfield, Mark J, Zanchetti, Alberto, Dominiczak, Anna F

“…Hypertension is a heritable and major contributor to the global burden of disease. The sum of rare and common genetic variants robustly identified so far…”
Get full text

Silicon core fibers: A new platform for quantum light generation by Rizzotti, Davide, Signorini, Stefano, Harvey, Clarissa, Fokine, Michael, Pruneri, Valerio

“…Integrated quantum sources are proving to be the most effective technology of sources for scalable quantum applications. A platform that satisfies all the…”
Get full text

AHR gene-dioxin interactions and birthweight in the Seveso Second Generation Health Study by Ames, Jennifer, Warner, Marcella, Mocarelli, Paolo, Brambilla, Paolo, Signorini, Stefano, Siracusa, Claudia, Huen, Karen, Holland, Nina, Eskenazi, Brenda

“…2, 3, 7, 8-tetrachlorodibenzo-p-dioxin (TCDD) is proposed to interfere with fetal growth via altered activity of the aryl hydrocarbon receptor (protein: AHR;…”
Get full text

Perinatal Exposure to Low Doses of Dioxin Can Permanently Impair Human Semen Quality by Mocarelli, Paolo, Gerthoux, Pier Mario, Needham, Larry L., Patterson, Donald G., Limonta, Giuseppe, Falbo, Rosanna, Signorini, Stefano, Bertona, Maria, Crespi, Carla, Sarto, Cecilia, Scott, Paul K., Turner, Wayman E., Brambilla, Paolo

“…Background: In recent decades, young men in some industrialized areas have reportedly experienced a decrease in semen quality. Objective: We examined effects…”
Get full text

Association between Diet Quality and Index of Non-Alcoholic Steatohepatitis in a Large Population of People with Type 2 Diabetes: Data from the TOSCA.IT Study by Vitale, Marilena, Della Pepa, Giuseppe, Costabile, Giuseppina, Bozzetto, Lutgarda, Cipriano, Paola, Signorini, Stefano, Leoni, Valerio, Riccardi, Gabriele, Vaccaro, Olga, Masulli, Maria

“…Background: There are still open questions with respect to the optimal dietary treatment in patients with type 2 diabetes (T2D) and coexisting non-alcoholic…”
Get full text

Definition of IgG Subclass-Specific Glycopatterns in Idiopathic Membranous Nephropathy: Aberrant IgG Glycoforms in Blood by Chinello, Clizia, de Haan, Noortje, Capitoli, Giulia, Trezzi, Barbara, Radice, Antonella, Pagani, Lisa, Criscuolo, Lucrezia, Signorini, Stefano, Galimberti, Stefania, Sinico, Renato Alberto, Wuhrer, Manfred, Magni, Fulvio

“…The podocyte injury, and consequent proteinuria, that characterize the pathology of idiopathic membranous nephropathy (IMN) is mediated by an autoimmune…”
Get full text

Sex‐related relationships between uric acid and target organ damage in hypertension by Maloberti, Alessandro, Maggioni, Simone, Occhi, Lucia, Triglione, Nicola, Panzeri, Francesco, Nava, Stefano, Signorini, Stefano, Falbo, Rosanna, Casati, Marco, Grassi, Guido, Giannattasio, Cristina

“…Heterogeneous results have been obtained in the relationship between serum uric acid (SUA) and target organ damage (TOD) in patients with hypertension. Clinic…”
Get full text

Variability of Black Carbon and Ultrafine Particle Concentration on Urban Bike Routes in a Mid-Sized City in the Po Valley (Northern Italy) by Lonati, Giovanni, Ozgen, Senem, Ripamonti, Giovanna, Signorini, Stefano

“…Cyclists might experience increased air pollution exposure, due to the proximity to traffic, and higher intake, due to their active travel mode and higher…”
Get full text

Dioxin Exposure, from Infancy through Puberty, Produces Endocrine Disruption and Affects Human Semen Quality by Mocarelli, Paolo, Gerthoux, Pier Mario, Patterson, Donald G., Silvano Milani, Giuseppe Limonta, Maria Bertona, Signorini, Stefano, Pierluigi Tramacere, Colombo, Laura, Carla Crespi, Brambilla, Paolo, Cecilia Sarto, Vittorio Carreri, Sampson, Eric J., Turner, Wayman E., Needham, Larry L.

“…BACKGROUND: Environmental toxicants are allegedly involved in decreasing semen quality in recent decades; however, definitive proof is not yet available. In…”
Get full text

Iron Stores, Hepcidin, and Aortic Stiffness in Individuals with Hypertension by Valenti, Luca, Maloberti, Alessandro, Signorini, Stefano, Milano, Marta, Cesana, Francesca, Cappellini, Fabrizio, Dongiovanni, Paola, Porzio, Marianna, Soriano, Francesco, Brambilla, Maura, Cesana, Giancarlo, Brambilla, Paolo, Giannattasio, Cristina, Fargion, Silvia

“…Iron accumulation within the arterial wall has been hypothesized to promote atherosclerosis progression. Aim of this study was to evaluate whether the hormone…”
Get full text

Normal Fasting Plasma Glucose and Risk of Type 2 Diabetes by Brambilla, Paolo, La Valle, Elisa, Falbo, Rosanna, Limonta, Giuseppe, Signorini, Stefano, Cappellini, Fabrizio, Mocarelli, Paolo

“…OBJECTIVE: To investigate the association of normal fasting plasma glucose (FPG) and the risk for type 2 diabetes. RESEARCH DESIGN AND METHODS: Data concerning…”
Get full text

Prognostic significance of the long pentraxin PTX3 in acute myocardial infarction by LATINI, Roberto, MAGGIONI, Aldo P, TARLI, Lorenzo, SCHWEIGER, Carlo, FRESCO, Claudio, CECERE, Rossana, TOGNONI, Gianni, MANTOVANI, Alberto, PERI, Giuseppe, GONZINI, Lucio, LUCCI, Donata, MOCARELLI, Paolo, VAGO, Luca, PASQUALINI, Fabio, SIGNORINI, Stefano, SOLDATESCHI, Dario

“…Inflammation has a pathogenetic role in acute myocardial infarction (MI). Pentraxin-3 (PTX3), a long pentraxin produced in response to inflammatory stimuli and…”
Get full text

Clinical and prognostic value of spot urinary creatinine in chronic heart failure - an analysis from GISSI-HF by ter Maaten, Jozine M, Maggioni, Aldo Pietro, Latini, Roberto, Masson, Serge, Tognoni, Gianni, Tavazzi, Luigi, Signorini, Stefano, Voors, Adriaan A, Damman, Kevin

“…Abstract Objectives This study aimed to identify patient characteristics associated with low urinary creatinine in morning spot urine and investigate its…”
Get full text