Search Results - "Signorini, D. F."

Predicting survival using simple clinical variables: a case study in traumatic brain injury by Signorini, David F, Andrews, Peter J D, Jones, Patricia A, Wardlaw, Joanna M, Miller, J Douglas

“…OBJECTIVES Prediction of patient outcome can be useful as an aid to clinical decision making, to explore possible biological mechanisms, and as part of the…”
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Transcranial cytokine gradients in patients requiring intensive care after acute brain injury by McKeating, E G, Andrews, P J, Signorini, D F, Mascia, L

“…After acute brain injury there may be increased intracranial production of cytokines, with activation of inflammatory cascades. We have sought to determine if…”
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Variations between countries in outcome after stroke in the International Stroke Trial (IST) by WEIR, N. U, SANDERCOCK, P. A. G, LEWIS, S. C, SIGNORINI, D. F, WARLOW, C. P

“…This study describes the large variations in outcome after stroke between countries that participated in the International Stroke Trial and seeks to define…”
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A Comparison of Higher-Order Bias Kernel Density Estimators by Jones, M. C., Signorini, D. F.

“…We consider many kernel-based density estimators, all theoretically improving bias from O(h 2 ), as the smoothing parameter h → 0, to O(h 4 ). Examples include…”
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Kernel Estimators for Univariate Binary Regression by Signorini, D. F, Jones, M. C

“…We present a rather thorough investigation of the use of kernel-based nonparametric estimators of the binary regression function in the case of a single…”
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Therapeutic hypothermia for head injury by Alderson, P, Gadkary, C, Signorini, D F

“…Induced hypothermia has been used in the treatment of head injury for many years. Encouraging results from small trials and laboratory studies led to renewed…”
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Adding insult to injury: the prognostic value of early secondary insults for survival after traumatic brain injury by Signorini, David F, Andrews, Peter J D, Jones, Patricia A, Wardlaw, Joanna M, Miller, J Douglas

“…OBJECTIVES To assess the prognostic value of summary measures of secondary physiological insult in addition to baseline clinical variables for patients with…”
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Inverse relation between Braak stage and cerebrovascular pathology in Alzheimer predominant dementia by Goulding, Jonathan M R, Signorini, David F, Chatterjee, Sanjukta, Nicoll, James A R, Stewart, Janice, Morris, Robert, Lammie, G Alistair

“…The most common neuropathological substrates of dementia are Alzheimer’s disease, cerebrovascular disease, and dementia with Lewy bodies. A preliminary,…”
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Dynamic balanced randomization for clinical trials by Signorini, D F, Leung, O, Simes, R J, Beller, E, Gebski, V J, Callaghan, T

“…Common methods of treatment allocation for multi-centre and/or stratified randomized clinical trials can result in substantial differences between the number…”
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A clinical evaluation of the Codman MicroSensor for intracranial pressure monitoring by F. SIGNORINI, D., SHAD, A., PIPER, I. R., STATHAM, P. F. X.

“…The strain-gauge Codman MicroSensor intracranial pressure (ICP) transducer has shown consistently good laboratory performance. To assess the practical…”
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A comparison of the Invos 3100 and the Critikon 2020 near‐infrared spectrophotometers as monitors of cerebral oxygenation by McKeating, E. G., Monjardino, J. R., Signorini, D. F., Souter, M. J., Andrews, P. J. D.

“…Assessment of cerebral oxygenation using near‐infrared spectroscopy in intensive care is increasing. We compared the ability of the Invos 3100 and the Critikon…”
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Therapeutic hypothermia for head injury by Gadkary, C S, Alderson, P, Signorini, D F

“…Induced hypothermia has been used in the treatment of head injury for many years. Encouraging results from small trials and laboratory studies led to renewed…”
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Glasgow Head Injury Outcome Prediction Program: an independent assessment by Nissen, Justin J, Jones, Patricia A, Signorini, David F, Murray, Lilian S, Teasdale, Graham M, Miller, J Douglas

“…Using an independent data set, the utility of the Glasgow Head Injury Outcome Prediction Program was investigated in terms of possible frequency of use and…”
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Treatment by a specialist surgical neuro-oncologist does not provide any survival advantage for patients with a malignant glioma by Z. B. LATIF, A., SIGNORINI, D. F., WHITTLE, I. R.

“…A bstract Todeterminewhether patientswith malignant glioma (glioblastoma and anaplastic astrocytoma) had longer survival times, and lower morbidity and…”
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The Edinburgh Extended Glasgow Outcome Scale (EEGOS): Rationale and Pilot Studies by Hellawell, D. J, Signorini, D. F

“…Describes pilot studies of the Edinburgh Extended Glasgow Outcome Scale (EEGOS), designed to retain the advantages of the GOS (a measure commonly used in head…”
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The influence of baseline prognostic variables on outcome after thrombolysis by WARDLAW, J. M, DORMAN, P. J, CANDELISE, L, SIGNORINI, D. F

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Meta-analysis: greater than the sum of its parts? by Souter, M J, Signorini, D F

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Reliability of the relative's questionnaire for assessment of outcome after brain injury by Hellawell, Deborah J., Pentland, Brian, Signorini, David F.

“…Purpose : The relative's questionnaire (RQ) was developed to assess outcome after brain injury. The present study investigated its test-retest reliability when…”
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Therapeutic hypothermia for head injury by Signorini, D F, Alderson, P

“…Mild to moderate induced hypothermia has been used in the treatment of head injury for over 50 years, although few randomised controlled trials have been…”
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Pineal region tumors and the role of stereotactic biopsy: review of the mortality, morbidity, and diagnostic rates in 370 cases by Whittle, I R, Signorini, D F

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