Search Results - "Signori, E. E."

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    pH fronts and tissue natural buffer interaction in gene electrotransfer protocols by Marino, M., Olaiz, N., Signori, E., Maglietti, F., Suárez, C., Michinski, S., Marshall, G.

    Published in Electrochimica acta (20-11-2017)
    “…[Display omitted] •In GET protocols, pulse length and intensity tune pH front- buffer fluctuation•During the ON pulse, pH front jumps forward, during the OFF…”
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    Gene electrotransfer of IL-2 and IL-12 plasmids effectively eradicated murine B16.F10 melanoma by Komel, T., Bosnjak, M., Kranjc Brezar, S., De Robertis, M., Mastrodonato, M., Scillitani, G., Pesole, G., Signori, E., Sersa, G., Cemazar, M.

    “…•Gene electrotransfer of IL-2 and IL-12 is an effective treatment for B16.F10 model.•Complete responses were obtained in 71% of mice treated with IL-2 and…”
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    Tissue damage modeling in gene electrotransfer: The role of pH by Olaiz, N., Signori, E., Maglietti, F., Soba, A., Suárez, C., Turjanski, P., Michinski, S., Marshall, G.

    “…Optimal gene electrotransfer (GET) requires a compromise between maximum transgene expression and minimal tissue damage. GET in skeletal muscle can be improved…”
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    Optimisation of electrotransfer of plasmid into skeletal muscle by pretreatment with hyaluronidase -increased expression with reduced muscle damage by MCMAHON, J. M, SIGNORI, E, WELLS, K. E, FAZIO, V. M, WELLS, D. J

    Published in Gene therapy (01-08-2001)
    “…The efficiency of plasmid gene transfer to skeletal muscle can be significantly improved by the application of an electrical field to the muscle following…”
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    BCR/ABL1 fusion transcripts generated from alternative splicing: implications for future targeted therapies in Ph+ leukaemias by Chiarella, P, Summa, V, De Santis, S, Signori, E, Picardi, E, Pesole, G, Saglio, G, Fazio, V M

    Published in Current molecular medicine (01-06-2012)
    “…Philadelphia (Ph+) positive leukaemias are an example of haematological malignant diseases where different chromosomal rearrangements involving both BCR and…”
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    Expression and heterodimer-binding activity of Ku70 and Ku80 in human non-melanoma skin cancer by Parrella, P, Mazzarelli, P, Signori, E, Perrone, G, Marangi, G F, Rabitti, C, Delfino, M, Prencipe, M, Gallo, A P, Rinaldi, M, Fabbrocini, G, Delfino, S, Persichetti, P, Fazio, V M

    Published in Journal of clinical pathology (01-11-2006)
    “…Background: Experimental data suggest that exposure to ultraviolet radiation may indirectly induce DNA double-strand breaks. Aim: To investigate the…”
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    Immune response at birth, long-term immune memory and 2 years follow-up after in-utero anti-HBV DNA immunization by FAZIO, V. M, RIA, F, BLOGNA, S, FIORETTI, D, IURESCIA, S, FILIPPETTI, R, RINALDI, M, FRANCO, E, ROSATI, P, CANNELLI, G, SIGNORI, E, PARRELLA, P, ZARATTI, L, IANNACE, E, MONEGO, G

    Published in Gene therapy (01-03-2004)
    “…Infections occurring at the end of pregnancy, during birth or by breastfeeding are responsible for the high toll of death among first-week infants. In-utero…”
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    The influence of maternal passive and light active smoking on intrauterine growth and body composition of the newborn by LUCIANO, A, BOLOGNANI, M, BIONDANI, P, GHIZZI, C, ZOPPI, G, SIGNORI, E

    Published in European journal of clinical nutrition (01-10-1998)
    “…To assess the influence of passive and light active smoking on the reduction of intrauterine growth of the foetus and on modifications in the body composition…”
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    Treatment of severe hypercholesterolemia in apolipoprotein E-deficient mice by intramuscular injection of plasmid DNA by RINALDI, M, CATAPANO, A. L, FAZIO, V. M, PARRELLA, P, CIAFRE, S. A, SIGNORI, E, SERIPA, D, UBOLDI, P, ANTONINI, R, RICCI, G, FARACE, M. G

    Published in Gene therapy (01-11-2000)
    “…We report on systemic delivery and long-term biological effects of apolipoprotein E (apoE) obtained by intramuscular (i.m.) plasmid DNA injection. ApoE plays…”
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    Anti-tumor immunity induced by CDR3-based DNA vaccination in a murine B-cell lymphoma model by Rinaldi, Monica, Fioretti, Daniela, Iurescia, Sandra, Signori, Emanuela, Pierimarchi, Pasquale, Seripa, Davide, Tonon, Giancarlo, Fazio, Vito Michele

    “…The idiotypic structure present on B-cell neoplasms is a tumor-specific antigen and an attractive target for immunotherapy. Here, the tumor protective effects…”
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    A somatic mutation in the 5′UTR of BRCA1 gene in sporadic breast cancer causes down-modulation of translation efficiency by Signori, Emanuela, Bagni, Claudia, Papa, Sara, Primerano, Beatrice, Rinaldi, Monica, Amaldi, Francesco, Fazio, Vito Michele

    Published in Oncogene (27-07-2001)
    “…Mutations in the 5′ UTR which cause increment/decrement of translation efficiency have been recently described as a novel molecular mechanism of disease…”
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    ApoE gene delivery inhibits severe hypercholesterolemia in newborn ApoE-KO mice by Signori, Emanuela, Rinaldi, Monica, Fioretti, Daniela, Iurescia, Sandra, Seripa, Davide, Perrone, Giuseppe, Norata, Giuseppe Danilo, Catapano, Alberico Luigi, Fazio, Vito Michele

    “…Apolipoprotein E, a key regulator in cholesterol-rich lipoprotein metabolism, is considered a strong candidate for treating hypercholesterolemia and…”
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