Search Results - "Sigal, J"
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Physical Activity/Exercise and Diabetes: A Position Statement of the American Diabetes Association
Published in Diabetes care (01-11-2016)Get full text
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Motivational interviewing to improve weight loss in overweight and/or obese patients: a systematic review and meta‐analysis of randomized controlled trials
Published in Obesity reviews (01-09-2011)“…Motivational interviewing, a directive, patient‐centred counselling approach focused on exploring and resolving ambivalence, has emerged as an effective…”
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Age-related decrements in heat dissipation during physical activity occur as early as the age of 40
Published in PloS one (12-12-2013)“…Older adults typically experience greater levels of thermal strain during physical efforts in the heat compared to young individuals. While this may be related…”
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4
Serum Urate Lowering with Allopurinol and Kidney Function in Type 1 Diabetes
Published in The New England journal of medicine (25-06-2020)“…In a double-blind trial, patients with type 1 diabetes and early-to-moderate diabetic kidney disease were randomly assigned to receive allopurinol, which may…”
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Heat stress in older individuals and patients with common chronic diseases
Published in Canadian Medical Association journal (CMAJ) (13-07-2010)“…Heat balance is easily disturbed during exposure to a warmer environment and with changes in metabolic heat production (due to physical activity). As the…”
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With some risk-taking and luck: A veterinarian's adventures in viral immunology
Published in PLoS pathogens (05-07-2018)Get full text
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Sequential Activation of Two Pathogen-Sensing Pathways Required for Type I Interferon Expression and Resistance to an Acute DNA Virus Infection
Published in Immunity (Cambridge, Mass.) (15-12-2015)“…Toll-like receptor 9 (TLR9), its adaptor MyD88, the downstream transcription factor interferon regulatory factor 7 (IRF7), and type I interferons (IFN-I) are…”
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Heat health planning: The importance of social and community factors
Published in Global environmental change (01-05-2011)“…Research highlights a- The influence of social and community level factors on morbidity and mortality during periods of extreme heat is poorly understood. a-…”
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Age-dependent susceptibility to a viral disease due to decreased natural killer cell numbers and trafficking
Published in The Journal of experimental medicine (25-10-2010)“…Although it is well known that aged hosts are generally more susceptible to viral diseases than the young, specific dysfunctions of the immune system directly…”
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CD94 Is Essential for NK Cell-Mediated Resistance to a Lethal Viral Disease
Published in Immunity (Cambridge, Mass.) (22-04-2011)“…It is well established that natural killer (NK) cells confer resistance to many viral diseases, but in only a few instances the molecular mechanisms whereby NK…”
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At what level of heat load are age-related impairments in the ability to dissipate heat evident in females?
Published in PloS one (19-03-2015)“…Studies have reported that older females have impaired heat loss responses during work in the heat compared to young females. However, it remains unclear at…”
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Overweight and obese teenagers: why is adolescence a critical period?
Published in Pediatric obesity (01-08-2012)“…Summary This paper discusses the critical period of adolescence and its potential role in the development and persistence of obesity. The adolescent years are…”
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Physical activity/exercise and type 2 diabetes
Published in Diabetes care (01-10-2004)“…Sigal et al discuss the developments on American Diabetes Association' technical review of exercise and type 2 diabetes. The developments include new…”
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Effects of Performing Resistance Exercise Before Versus After Aerobic Exercise on Glycemia in Type 1 Diabetes
Published in Diabetes care (01-04-2012)“…To determine the effects of exercise order on acute glycemic responses in individuals with type 1 diabetes performing both aerobic and resistance exercise in…”
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Resistance to ectromelia virus infection requires cGAS in bone marrow-derived cells which can be bypassed with cGAMP therapy
Published in PLoS pathogens (01-12-2019)“…Cells sensing infection produce Type I interferons (IFN-I) to stimulate Interferon Stimulated Genes (ISGs) that confer resistance to viruses. During…”
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Resistance To Poxvirus Lethality Does Not Require the Necroptosis Proteins RIPK3 or MLKL
Published in Journal of virology (28-02-2023)“…Receptor-interacting protein kinase 3 (RIPK3) and mixed lineage kinase domain-like pseudokinase (MLKL) are proteins that are critical for necroptosis, a…”
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Randomized Controlled Trial of Resistance or Aerobic Exercise in Men Receiving Radiation Therapy for Prostate Cancer
Published in Journal of clinical oncology (20-01-2009)“…Radiotherapy for prostate cancer (PCa) may cause unfavorable changes in fatigue, quality of life (QOL), and physical fitness. We report results from the…”
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Viral infection modulates Qa-1b in infected and bystander cells to properly direct NK cell killing
Published in The Journal of experimental medicine (03-05-2021)“…Natural killer (NK) cell activation depends on the signaling balance of activating and inhibitory receptors. CD94 forms inhibitory receptors with NKG2A and…”
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Helium Ion Microscopy (HIM) for the imaging of biological samples at sub-nanometer resolution
Published in Scientific reports (17-12-2013)“…Scanning Electron Microscopy (SEM) has long been the standard in imaging the sub-micrometer surface ultrastructure of both hard and soft materials. In the case…”
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Meta-analysis of the effect of structured exercise training on cardiorespiratory fitness in Type 2 diabetes mellitus
Published in Diabetologia (01-08-2003)“…Low cardiorespiratory fitness is a powerful and independent predictor of mortality in people with diabetes. Several studies have examined the effects of…”
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