Search Results - "Siga, Humam"
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Phospholamban antisense oligonucleotides improve cardiac function in murine cardiomyopathy
Published in Nature communications (30-08-2021)“…Heart failure (HF) is a major cause of morbidity and mortality worldwide, highlighting an urgent need for novel treatment options, despite recent improvements…”
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Epigenetic modulators link mitochondrial redox homeostasis to cardiac function in a sex-dependent manner
Published in Nature communications (20-03-2024)“…While excessive production of reactive oxygen species (ROS) is a characteristic hallmark of numerous diseases, clinical approaches that ameliorate oxidative…”
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BLR: a flexible pipeline for haplotype analysis of multiple linked-read technologies
Published in Nucleic acids research (11-12-2023)“…Abstract Linked-read sequencing promises a one-method approach for genome-wide insights including single nucleotide variants (SNVs), structural variants, and…”
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Myosin binding protein-C and hypertrophic cardiomyopathy: role of altered C10 domain
Published in Cardiovascular research (01-12-2019)Get full text
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Abstract 13376: Epigenetic Landscape in Mybpc3 Knockout Mice and Effects on Gene Expression
Published in Circulation (New York, N.Y.) (19-11-2019)“…Epigenetic regulators, such as 5 methylcytosine (5mC), 5 hydroxymethylcytosine (5hmC), and miRNAs are important determinants of gene expressions, but the…”
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Abstract 13298: Methylation, Mis-Splicing and Expression of Pathological Isoforms in a Disease Causing Csrp3/Mlp Mutation
Published in Circulation (New York, N.Y.) (19-11-2019)“…CSRP3 (cysteine rich protein or muscle LIM protein / MLP) is expressed in striated muscle and localizes, apart from other compartments, to the sarcomeric…”
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