Search Results - "Sifat, Ali Ehsan"
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Blood-Brain Barrier Protection as a Therapeutic Strategy for Acute Ischemic Stroke
Published in The AAPS journal (01-07-2017)“…The blood-brain barrier (BBB) is a vital component of the neurovascular unit (NVU) containing tight junctional (TJ) proteins and different ion and nutrient…”
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Brain Energy Metabolism in Ischemic Stroke: Effects of Smoking and Diabetes
Published in International journal of molecular sciences (31-07-2022)“…Proper regulation of energy metabolism in the brain is crucial for maintaining brain activity in physiological and different pathophysiological conditions…”
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Nicotinamide Mononucleotide: Exploration of Diverse Therapeutic Applications of a Potential Molecule
Published in Biomolecules (Basel, Switzerland) (21-01-2019)“…Nicotinamide mononucleotide (NMN) is a nucleotide that is most recognized for its role as an intermediate of nicotinamide adenine dinucleotide (NAD+)…”
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Offsetting the impact of smoking and e-cigarette vaping on the cerebrovascular system and stroke injury: Is Metformin a viable countermeasure?
Published in Redox biology (01-10-2017)“…Recently published in vitro and in vivo findings strongly suggest that BBB impairment and increased risk for stroke by tobacco smoke (TS) closely resemble that…”
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Maternal e-cigarette use can disrupt postnatal blood-brain barrier (BBB) integrity and deteriorates motor, learning and memory function: influence of sex and age
Published in Fluids and barriers of the CNS (10-03-2023)“…Electronic nicotine delivery systems (ENDS), also commonly known as electronic cigarettes (e-cigs) are considered in most cases as a safer alternative to…”
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A convenient UHPLC-MS/MS method for routine monitoring of plasma and brain levels of nicotine and cotinine as a tool to validate newly developed preclinical smoking model in mouse
Published in BMC neuroscience (11-10-2017)“…A sensitive, rapid and selective UHPLC-MS/MS method has been developed and validated for the quantification of Nicotine (NT) and Cotinine (CN) using…”
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Metformin ameliorates neuroinflammatory environment for neurons and astrocytes during in vitro and in vivo stroke and tobacco smoke chemical exposure: Role of Nrf2 activation
Published in Redox biology (01-09-2024)“…Despite the protective nature of the blood-brain barrier (BBB) and brain-protecting tissues, some types of CNS injury or stress can cause cerebral cytokine…”
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Impact of in-utero electronic cigarette exposure on neonatal neuroinflammation, oxidative stress and mitochondrial function
Published in Frontiers in pharmacology (24-08-2023)“…Introduction: Despite the prevalence of the perception that electronic cigarettes (e-cig) are a safer alternative to tobacco smoke, growing concern about their…”
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Short-term exposure to JUUL electronic cigarettes can worsen ischemic stroke outcome
Published in Fluids and barriers of the CNS (09-09-2022)“…The short and long-term health effects of JUUL electronic cigarette (e-Cig) are largely unknown and warrant extensive research. We hypothesized that JUUL…”
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Genetic polymorphisms of GSTP1, XRCC1, XPC and ERCC1: prediction of clinical outcome of platinum-based chemotherapy in advanced non-small cell lung cancer patients of Bangladesh
Published in Molecular biology reports (01-09-2020)“…Inter-individual genetic makeup can trigger variability in platinum-based chemotherapeutic responses and corresponding adverse drug reactions and toxicities…”
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Novel approaches for the delivery of therapeutics in ischemic stroke
Published in Drug discovery today (01-03-2020)“…•Ischemic stroke is one of the leading causes of death and disability worldwide.•Current therapeutic options for stroke are use of tPA or endovascular…”
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The Role of Smoking and Nicotine in the Transmission and Pathogenesis of COVID-19
Published in The Journal of pharmacology and experimental therapeutics (01-12-2020)“…Coronavirus disease 2019 (COVID-19), caused by the severe acute respiratory syndrome coronavirus 2 virus, is turning out to be one of the most devastating…”
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13
Prenatal E‐Cigarette Use Disrupts Blood‐Brain Barrier (BBB) Integrity and Induces Pro‐Inflammatory Cytokines in Postnatal Brain
Published in The FASEB journal (01-05-2022)“…Purpose Electronic cigarette (e‐Cig) is often considered as a safer alternative to smoking for pregnant women however, its potential toxic effect on neonatal…”
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Maternal Electronic Cigarette Use Can Enhance Offspring Susceptibility to Hypoxic‐Ischemic Brain Injury
Published in The FASEB journal (01-04-2019)“…Prenatal exposure to tobacco smoke and nicotine is believed to interfere with fetal brain development predisposing offspring to different neurobehavioral and…”
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Studies on diketopiperazine and dipeptide analogs as opioid receptor ligands
Published in European journal of medicinal chemistry (05-06-2023)“…Using the structure of gliotoxin as a starting point, we have prepared two different chemotypes with selective affinity to the kappa opioid receptor (KOR)…”
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The neuroprotective role of the brain opioid system in stroke injury
Published in Drug discovery today (01-07-2018)“…•Stroke is one of the most devastating brain disorders worldwide.•tPA is the only US FDA approved drug for the treatment of stroke.•Neuroprotective agents are…”
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