Search Results - "Sifaoui, Inès"
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VEGFC Gene Expression Is Associated with Tumor Progression and Disease-Free Survival in Cutaneous Squamous Cell Carcinoma
Published in International journal of molecular sciences (27-12-2023)“…Cutaneous squamous cell carcinoma (CSCC) is one of the most common cancers in the skin. CSCC belongs to the non-melanoma skin cancers, and its incidence is…”
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Withaferin A-silyl ether analogs as potential anti-kinetoplastid agents targeting the programmed cell death
Published in Biomedicine & pharmacotherapy (01-01-2023)“…Current therapies of leishmaniasis and Chagas disease, two of the most widespread neglected tropical diseases, have limited efficacy and toxic side effects. In…”
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3
A giant virus infecting the amoeboflagellate Naegleria
Published in Nature communications (24-04-2024)“…Giant viruses ( Nucleocytoviricota ) are significant lethality agents of various eukaryotic hosts. Although metagenomics indicates their ubiquitous…”
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An approach to the effects of longevity, sexual maturity, and reproduction on telomere length and oxidative stress in different Psittacidae species
Published in Frontiers in genetics (20-03-2023)“…Aging is a multifactorial process that includes molecular changes such as telomere shortening. Telomeres shorten progressively with age in vertebrates, and…”
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Green, zero-waste pathway to fabricate supported nanocatalysts and anti-kinetoplastid agents from sugarcane bagasse
Published in Waste management (Elmsford) (01-01-2023)“…[Display omitted] •Two functional materials were fabricated from one agrowaste.•Green treatment of the biomass was proposed, maceration and ultrasonication.•A…”
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Influence of salt and temperature in the growth of pathogenic free-living amoebae
Published in Frontiers in microbiology (15-02-2024)“…Free-living amoebae are an extensive group of protistans that can be found in a wide variety of environments. Among them, the genus and stand out as two of the…”
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DNA damage (8-OHdG) and telomere length in captive Psittacidae birds with different longevity
Published in Frontiers in veterinary science (07-08-2024)“…Aging is a complex process influenced by internal and external factors. Oxidative stress damages DNA, leading to 8-hydroxy-2' deoxyguanosine formation…”
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Sesquiterpenoids and flavonoids from Inula viscosa induce programmed cell death in kinetoplastids
Published in Biomedicine & pharmacotherapy (01-10-2020)“…[Display omitted] •Neglected tropical diseases such as leishmaniasis and American trypanosomiasis are among the potentially life-threatening parasitic…”
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Telomere- and oxidative stress dynamics in Psittacidae species with different longevity trajectories
Published in GeroScience (25-10-2024)“…Telomeres, conserved DNA sequences at chromosome ends, naturally shorten with age, exacerbated by external factors like environmental challenges and…”
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10
Toxic effects of selected proprietary dry eye drops on Acanthamoeba
Published in Scientific reports (04-06-2018)“…Amoebae of the genus Acanthamoeba are ubiquitous protists that have been isolated from many sources such as soils, water and the air. They are responsible for…”
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Exploring therapeutic approaches against Naegleria fowleri infections through the COVID box
Published in International journal for parasitology -- drugs and drug resistance (01-08-2024)“…Naegleria fowleri, known as the brain-eating amoeba, is the pathogen that causes the primary amoebic meningoencephalitis (PAM), a severe neurodegenerative…”
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12
Fluvastatin and atorvastatin induce programmed cell death in the brain eating amoeba Naegleria fowleri
Published in Biomedicine & pharmacotherapy (01-10-2020)“…[Display omitted] •There is an urgent need for novel therapeutic agents against PAM.•Atorvastatin and fluvastatin showed high effects in vitro against N…”
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13
Multi-target withaferin-A analogues as promising anti-kinetoplastid agents through the programmed cell death
Published in Biomedicine & pharmacotherapy (01-08-2023)“…Leishmaniasis and Chagas disease, two of the most prevalent neglected tropical diseases, are a world health problem. The harsh reality of these infective…”
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14
Bioguided Isolation of Active Compounds from Rhamnus alaternus against Methicillin-Resistant Staphylococcus aureus (MRSA) and Panton-Valentine Leucocidin Positive Strains (MSSA-PVL)
Published in Molecules (Basel, Switzerland) (19-07-2021)“…Despite intensified efforts to develop an effective antibiotic, S. aureus is still a major cause of mortality and morbidity worldwide. The multidrug resistance…”
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15
Staurosporine as a Potential Treatment for Acanthamoeba Keratitis Using Mouse Cornea as an Ex Vivo Model
Published in Marine drugs (18-09-2024)“…is a ubiquitous genus of amoebae that can trigger a severe and progressive ocular disease known as Keratitis (AK). Furthermore, current treatment protocols are…”
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Isobenzofuran-1(3H)-one derivatives: Amoebicidal activity and program cell death in Acanthamoeba castellanii Neff
Published in Biomedicine & pharmacotherapy (01-06-2022)“…The genus Acanthamoeba is characterized by being a group of ubiquitous and free-living amoebae that inhabit a variety of environments. Generally, human…”
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Programmed cell death in Acanthamoeba castellanii Neff induced by several molecules present in olive leaf extracts
Published in PloS one (31-08-2017)“…Therapy against Acanthamoeba infections such as Granulomatous Amoebic Encephalitis (GAE) and Acanthamoeba Keratitis (AK), remains as an issue to be solved due…”
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Cyclolauranes as plausible chemical scaffold against Naegleria fowleri
Published in Biomedicine & pharmacotherapy (01-05-2022)“…Primary amoebic meningoencephalitis (PAM) is a central nervous system (CNS) disease caused by Naegleria fowleri that mainly affects children and young adults…”
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Gongolarones as antiamoeboid chemical scaffold
Published in Biomedicine & pharmacotherapy (01-02-2023)“…Free Living Amoeba (FLA) infections caused by Acanthamoeba genus include chronic nervous system diseases such as Granulomatous Amoebic Encephalitis (GAE), or a…”
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Chamigrane-Type Sesquiterpenes from Laurencia dendroidea as Lead Compounds against Naegleria fowleri
Published in Marine drugs (31-03-2023)“…is an opportunistic protozoon that can be found in warm water bodies. It is the causative agent of the primary amoebic meningoencephalitis. Focused on our…”
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