Simultaneous acquisition of dual analyser-based phase contrast X-ray images for small animal imaging

Abstract Analyser-based phase contrast X-ray imaging can provide high-contrast images of biological tissues with exquisite sensitivity to the boundaries between tissues. The phase and absorption information can be extracted by processing multiple images acquired at different analyser orientations. R...

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Bibliographic Details
Published in:	European journal of radiology Vol. 68; no. 3; pp. S49 - S53
Main Authors:	Kitchen, Marcus J, Pavlov, Konstantin M, Hooper, Stuart B, Vine, David J, Siu, Karen K.W, Wallace, Megan J, Siew, Melissa L.L, Yagi, Naoto, Uesugi, Kentaro, Lewis, Rob A
Format:	Journal Article Conference Proceeding
Language:	English
Published:	Amsterdam Elsevier Ireland Ltd 01-12-2008 Elsevier
Subjects:	Algorithms Animal imaging Animals Animals, Newborn Biological and medical sciences Dogs Dynamic systems Imaging, Three-Dimensional - methods Imaging, Three-Dimensional - veterinary Investigative techniques, diagnostic techniques (general aspects) Medical sciences Phase contrast Phase retrieval Radiographic Image Enhancement - methods Radiographic Image Interpretation, Computer-Assisted - methods Radiography, Thoracic - veterinary Radiology Refractometry - methods Refractometry - veterinary Reproducibility of Results Sensitivity and Specificity Tomography, X-Ray - methods Tomography, X-Ray - veterinary Animal imaging Phase contrast Dynamic systems Phase retrieval Nuclear medicine Animal Radiology
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Summary:	Abstract Analyser-based phase contrast X-ray imaging can provide high-contrast images of biological tissues with exquisite sensitivity to the boundaries between tissues. The phase and absorption information can be extracted by processing multiple images acquired at different analyser orientations. Recording both the transmitted and diffracted beams from a thin Laue analyser crystal can make phase retrieval possible for dynamic systems by allowing full field imaging. This technique was used to image the thorax of a mechanically ventilated newborn rabbit pup using a 25 keV beam from the SPring-8 synchrotron radiation facility. The diffracted image was produced from the (1 1 1) planes of a 50 mm × 40 mm, 100 μm thick Si analyser crystal in the Laue geometry. The beam and analyser were large enough to image the entire chest, making it possible to observe changes in anatomy with high contrast and spatial resolution.
Bibliography:	ObjectType-Article-1 SourceType-Scholarly Journals-1 ObjectType-Feature-2 content type line 23
ISSN:	0720-048X 1872-7727
DOI:	10.1016/j.ejrad.2008.04.028