Search Results - "Sies, H"

Oxidative stress: oxidants and antioxidants by Sies, H

“…An imbalance between oxidants and antioxidants in favour of the oxidants, potentially leading to damage, is termed 'oxidative stress'. Oxidants are formed as a…”
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Plasma levels of vitamin E and carotenoids are decreased in patients with Nonalcoholic Steatohepatitis (NASH) by Erhardt, Andreas, Stahl, W, Sies, H, Lirussi, F, Donner, A, Häussinger, D

“…Oxidative stress is suggested to play an important role in the pathogenesis of nonalcoholic steatohepatitis (NASH). The present study was aimed to compare…”
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Use of isolated liver perfusion in metabolic studies: ground-laying work in experimental hepatology by Sies, H

“…Modern metabolic research in hepatology employs non-invasive techniques of the whole organism, and it includes studying the intact organ. Following recent…”
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Vitamins E and C, beta-carotene, and other carotenoids as antioxidants by Sies, H, Stahl, W

“…Tocopherols and tocotrienols (vitamin E), ascorbic acid (vitamin C), and the carotenoids react with free radicals, notably peroxyl radicals, and with singlet…”
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Biological Redox Systems and Oxidative Stress by Sies, H

“…This account revolves around fascination and excitement with science. Early curiosity and fortunate opportunities can lead to a satisfying career. The…”
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An encapsulated fruit and vegetable juice concentrate increases skin microcirculation in healthy women by De Spirt, S, Sies, H, Tronnier, H, Heinrich, U

“…Microcirculation in the dermis of the skin is important for nutrient delivery to this tissue. In this study, the effects of a micronutrient concentrate (Juice…”
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Oxidative stress: from basic research to clinical application by Sies, H

“…The occurrence of reactive oxygen species, known as pro-oxidants, is an attribute of normal aerobic life. The steady-state formation of pro-oxidants is…”
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Anticoccidial and antiinflammatory activity of garlic in murine Eimeria papillata infections by Dkhil, M.A., Abdel-Baki, A.S., Wunderlich, F., Sies, H., Al-Quraishy, S.

“…Coccidiosis with the protozoan parasite Eimeria as the infectious agent causes enormous economic losses, particularly in poultry farms. Here, we investigated…”
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Lycopene oxidation product enhances gap junctional communication by Aust, O., Ale-Agha, N., Zhang, L., Wollersen, H., Sies, H., Stahl, W.

“…Carotenoids as well as their metabolites and oxidation products stimulate gap junctional communication (GJC) between cells, which is thought to be one of the…”
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Ebselen: prospective therapy for cerebral ischaemia by Parnham, M, Sies, H

“…Stroke occurs due to haemorrhage or occlusive injury and results in ischaemia and reperfusion injury. A variety of destructive mechanisms are involved…”
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Macular Pigments Lutein and Zeaxanthin as Blue Light Filters Studied in Liposomes by Junghans, Angelika, Sies, Helmut, Stahl, Wilhelm

“…Lutein and zeaxanthin are the predominant carotenoids in the human macula lutea. Epidemiological data suggest that an increased intake of a lutein-rich diet…”
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Dietary tomato paste protects against ultraviolet light-induced erythema in humans by Stahl, W, Heinrich, U, Wiseman, S, Eichler, O, Sies, H, Tronnier, H

“…Carotenoids are efficient antioxidants capable of scavenging reactive oxygen species generated under conditions of photooxidative stress. It has been shown…”
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Uptake of lycopene and its geometrical isomers is greater from heat-processed than from unprocessed tomato juice in humans by Stahl, W, Sies, H

“…Lycopene and beta-carotene are the most abundant carotenoids in human blood and tissues. Although lacking provitamin A activity, lycopene may be biologically…”
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Lycopene: antioxidant and biological effects and its bioavailability in the human by Sies, H, Stahl, W

“…Lycopene is a non-provitamin A carotenoid present in human blood and tissues. The major dietary sources of lycopene for the human are tomatoes and tomato…”
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Nitric oxide-mediated inhibition of androgen receptor activity: possible implications for prostate cancer progression by CRONAUER, M. V, INCE, Y, ACKERMANN, R, KRÖNCKE, K.-D, ENGERS, R, RINNAB, L, WEIDEMANN, W, SUSCHEK, C. V, BURCHARDT, M, KLEINERT, H, WIEDENMANN, J, SIES, H

“…Chronic inflammation increases the risk of cancer and many cancers, including prostate cancer, arise at sites of chronic inflammation. Inducible nitric oxide…”
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Oxidative LDL modification is increased in vascular dementia and is inversely associated with cognitive performance by Li, L, Willets, R S, Polidori, M C, Stahl, W, Nelles, G, Sies, H, Griffiths, H R

“…It is not known whether the association between increased plasma homocysteine (Hcy) associated with LDL modification and propensity for LDL uptake by…”
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Antioxidant defense systems: the role of carotenoids, tocopherols, and thiols by Di Mascio, P, Murphy, ME, Sies, H

“…Reactive oxygen species occur in tissues and can damage DNA, proteins, carbohydrates, and lipids. These potentially deleterious reactions are controlled by a…”
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Peroxynitrite activates the phosphoinositide 3-kinase/Akt pathway in human skin primary fibroblasts by Klotz, L O, Schieke, S M, Sies, H, Holbrook, N J

“…Peroxynitrite is a potent oxidizing and nitrating species formed in a diffusion-limited reaction between nitrogen monoxide and superoxide. It induces apoptosis…”
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Even after UVA-exposure will nitric oxide protect cells from reactive oxygen intermediate-mediated apoptosis and necrosis by Suschek, C V, Briviba, K, Bruch-Gerharz, D, Sies, H, Kröncke, K D, Kolb-Bachofen, V

“…Reactive oxygen species (ROS) play a pivotal role in UVA-induced cell damage. As expression of the inducible nitric oxide synthase (iNOS) is a normal response…”
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Identification of cytosolic leucyl aminopeptidase (EC 3.4.11.1) as the major cysteinylglycine-hydrolysing activity in rat liver by Jösch, Claudio, Klotz, Lars-Oliver, Sies, Helmut

“…Cysteinylglycine hydrolysis is a step in the metabolism of glutathione and glutathione S-conjugates. We had previously observed that in rat liver the enzymatic…”
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